| Tag | Content |
|---|
| CPLM ID | CPLM-006385 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable intramembrane protease YKL100C |
Protein Synonyms/Alias | |
Gene Name | YKL100C; YKL450 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 246 | DDNEDLNKIGGFVTN | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | May act as intramembrane protease (By similarity). |
Sequence Annotation | MOTIF 477 479 PAL.
ACT_SITE 366 366 By similarity.
ACT_SITE 411 411 By similarity. |
Keyword | Complete proteome; Endoplasmic reticulum; Hydrolase; Membrane; Protease; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 587 AA |
Protein Sequence | MDKYLNSFVD HLSEWSSRAF RNNSSSANQS ASNKELEQVF EQINAIVENH NNKLTTAFDK 60
ISYRVAHKIT HLVESHSLVF NYATLVLIAS ALVVIGSFTS ISSIPFTALP PTREHSLFDP 120
TDFDVDHDCH VIYRENDEDK KKKKKSKRFF DMMDEKHAII LPLTSGCTLL ALYFVIKKLH 180
LNWLKYVVKI LNFNITLLNI PAGTFVYSYF LNSLFRNLSH LASWNPLVVL PRYRVTIADD 240
NEDLNKIGGF VTNLNYKDGL TNSVVHKKTL DEIEKDHWMK HFYRRELVEP KDIKSKRQIS 300
NMYLNSALIV SFVLSIVSTV YFYLSPNDWL ISNAVSMNMA IWSIAQLKLK NLKSGALILI 360
ALFFYDICFV FGTDVMVTVA TNLDIPVKLS LPVKFNTAQN NFNFSILGLG DIALPGMFIA 420
MCYKYDIWKW HLDHDDTEFH FLNWSYVGKY FITAMVSYVA SLVSAMVSLS IFNTAQPALL 480
YIVPSLLIST ILVACWNKDF KQFWNFQYDT IEVDKSLKKA IEKKENSITY STFILSEYYN 540
DADKYALLGD DVNENFDDDE EFVQEEDLSD SSEEELSEED LLDDESS 587 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; ISM:SGD. GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |