CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033798
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Suppressor of Ty 4 homolog 1 (S. cerevisiae), isoform CRA_b 
Protein Synonyms/Alias
 Transcription elongation factor SPT4 
Gene Name
 SUPT4H1 
Gene Synonyms/Alias
 hCG_2002775 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
40WQRVSNFKPGVYAVSubiquitination[1, 2, 3, 4]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 76 AA 
Protein Sequence
MKGNREMVYD CTSSSFDGII AMMSPEDSWV SKWQRVSNFK PGVYAVSVTG RLPQGIVREL 60
KSRGVAYKSR DTAIKT 76 
Gene Ontology
 GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IEA:Compara. 
Interpro
 IPR016046; Spt4-like.
 IPR022800; Spt4/RpoE2_Znf. 
Pfam
 PF06093; Spt4 
SMART
  
PROSITE
  
PRINTS