CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005815
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock 70 kDa protein cognate 5 
Protein Synonyms/Alias
  
Gene Name
 Hsc70-5 
Gene Synonyms/Alias
 Hsc5; CG8542 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
94PSHVAFTKDGERLVGacetylation[1]
133RFDDPEVKKDITNLSacetylation[1]
142DITNLSYKVVKASNGacetylation[1]
234ALAYGMDKTEDKIIAacetylation[1]
360SLVGDLIKRTIQPCQacetylation[1]
600ETKMEEFKSQLPAEEacetylation[1]
613EECEKLKKEIADLRTacetylation[1]
653KLFELAYKKMSAEREacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
 MOD_RES 86 86 Phosphothreonine.  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Phosphoprotein; Reference proteome; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 686 AA 
Protein Sequence
MLRVPKFLPR LARQAGVVPS HMSGASSMFR NLPGASNGIS SQLRYKSGEV KGAVIGIDLG 60
TTNSCLAVME GKQAKVIENA EGARTTPSHV AFTKDGERLV GMPAKRQAVT NSANTFYATK 120
RLIGRRFDDP EVKKDITNLS YKVVKASNGD AWVSSTDGKV YSPSQIGAFI LMKMKETAEA 180
YLNTPVKNAV VTVPAYFNDS QRQATKDAGQ IAGLNVLRVI NEPTAAALAY GMDKTEDKII 240
AVYDLGGGTF DISILEIQKG VFEVKSTNGD TLLGGEDFDN HIVNFLVAEF KKDSGIDIRK 300
DNIAMQRLKE AAEKAKCELS SSQQTDINLP YLTMDAAGPQ HMNLKLTRSK LESLVGDLIK 360
RTIQPCQKAL SDAEVSKSEI GEVLLVGGMT RMPKVQSTVQ ELFGRQPSRS VNPDEAVAVG 420
AAVQGGVLAG DVTDVLLLDV TPLSLGIETL GGVFTRLISR NTTIPTKKSQ VFSTASDGQT 480
QVEIKVHQGE REMANDNKLL GSFTLVGIPP APRGVPQIEV VFDIDANGIV HVSAKDKGTG 540
KEQQIVIQSS GGLSKDEIEN MIKKAEEYAT ADKQKRELIE IVNQGESIVH DTETKMEEFK 600
SQLPAEECEK LKKEIADLRT LLANKETADL EEVRKATSSL QQSSLKLFEL AYKKMSAERE 660
SNAGAGSSDS SSSSDTSGEA KKEEKN 686 
Gene Ontology
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR012725; Chaperone_DnaK.
 IPR018181; Heat_shock_70_CS.
 IPR013126; Hsp_70_fam. 
Pfam
 PF00012; HSP70 
SMART
  
PROSITE
 PS00297; HSP70_1
 PS00329; HSP70_2
 PS01036; HSP70_3 
PRINTS
 PR00301; HEATSHOCK70.