CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001051
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein-tyrosine sulfotransferase 1 
Protein Synonyms/Alias
 Tyrosylprotein sulfotransferase 1; TPST-1 
Gene Name
 Tpst1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
282AGGVSLSKVERSTDQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides. 
Sequence Annotation
 CARBOHYD 60 60 N-linked (GlcNAc...) (Potential).
 CARBOHYD 262 262 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 370 AA 
Protein Sequence
MVGKLKQNLL LACLVISSVT VFYLGQHAME CHHRIEERSQ PARLENPKAT VRAGLDIKAN 60
KTFTYHKDMP LIFIGGVPRS GTTLMRAMLD AHPDIRCGEE TRVIPRILAL KQMWSRSSKE 120
KIRLDEAGVT DEVLDSAMQA FLLEVIVKHG EPAPYLCNKD PFALKSLTYL ARLFPNAKFL 180
LMVRDGRASV HSMISRKVTI AGFDLNSYRD CLTKWNRAIE TMYNQCMEVG YKKCMLVHYE 240
QLVLHPERWM RTLLKFLHIP WNHSVLHHEE MIGKAGGVSL SKVERSTDQV IKPVNVGALS 300
KWVGKIPPDV LQDMAVIAPM LAKLGYDPYA NPPNYGKPDP KILENTRRVY KGEFQLPDFL 360
KEKPQTEQVE 370 
Gene Ontology
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0008476; F:protein-tyrosine sulfotransferase activity; IEA:EC.
 GO:0006478; P:peptidyl-tyrosine sulfation; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR026634; TPST. 
Pfam
  
SMART
  
PROSITE
  
PRINTS