CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006898
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SWI5-dependent HO expression protein 3 
Protein Synonyms/Alias
  
Gene Name
 SHE3 
Gene Synonyms/Alias
 YBR130C; YBR1005 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
219NKFNDSVKDLKSLETubiquitination[1]
228LKSLETEKDSKLSKIubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud. 
Sequence Annotation
 MOD_RES 343 343 Phosphoserine.
 MOD_RES 394 394 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; Endoplasmic reticulum; Membrane; mRNA transport; Phosphoprotein; Reference proteome; RNA-binding; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 425 AA 
Protein Sequence
MSDQDNTQTS SSKLAPHHNI FMANLESSPT KDRNTSSQNA SSSRVIESLH DQIDMLTKTN 60
LQLTTQSQNL LSKLELAQSK ESKLLENLNL LKNENENLNS IFERKNKKLK ELEKDYSELS 120
NRYNEQKEKM DQLSKLAKNS SAIEQSCSEK LQNMEVNYNS LLESQNLYRD HYSDEISKLN 180
EKIGLLELEL SNQNLNYGSD TSSNSDIELN LNKFNDSVKD LKSLETEKDS KLSKIITHSL 240
DELNLQSWLN LYQTNENLIS TFAEKMDLKD VLKRNDEKIS NKGAVVQTLK KNVQTQVESN 300
NADALSSNNA QDMLPIKMVK LRKTPNTNDS SSNGNSSNNK RRSFYTASPL LSSGSIPKSA 360
SPVLPGVKRT ASVRKPSSSS SKTNVTHNND PSTSPTISVP PGVTRTVSST HKKKGNSMVV 420
HGAQS 425 
Gene Ontology
 GO:0005934; C:cellular bud tip; IDA:SGD.
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0003729; F:mRNA binding; IDA:SGD.
 GO:0048309; P:endoplasmic reticulum inheritance; IMP:SGD.
 GO:0008298; P:intracellular mRNA localization; IMP:SGD.
 GO:0007533; P:mating type switching; IMP:SGD.
 GO:0051028; P:mRNA transport; IEA:UniProtKB-KW. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS