CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010320
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutamate-pyruvate aminotransferase AlaC 
Protein Synonyms/Alias
  
Gene Name
 alaC 
Gene Synonyms/Alias
 yfdZ; b2379; JW2376 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
260IGFMVGNKTLVSALAacetylation[1]
348MGSLEFAKKLLNEAKacetylation[1]
391RQAIRGIKAMFRADGacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Involved in the biosynthesis of alanine. 
Sequence Annotation
 MOD_RES 244 244 N6-(pyridoxal phosphate)lysine (By  
Keyword
 Aminotransferase; Complete proteome; Cytoplasm; Pyridoxal phosphate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 412 AA 
Protein Sequence
MADTRPERRF TRIDRLPPYV FNITAELKMA ARRRGEDIID FSMGNPDGAT PPHIVEKLCT 60
VAQRPDTHGY STSRGIPRLR RAISRWYQDR YDVEIDPESE AIVTIGSKEG LAHLMLATLD 120
HGDTVLVPNP SYPIHIYGAV IAGAQVRSVP LVEGVDFFNE LERAIRESYP KPKMMILGFP 180
SNPTAQCVEL EFFEKVVALA KRYDVLVVHD LAYADIVYDG WKAPSIMQVP GARDVAVEFF 240
TLSKSYNMAG WRIGFMVGNK TLVSALARIK SYHDYGTFTP LQVAAIAALE GDQQCVRDIA 300
EQYKRRRDVL VKGLHEAGWM VEMPKASMYV WAKIPEPYAA MGSLEFAKKL LNEAKVCVSP 360
GIGFGDYGDT HVRFALIENR DRIRQAIRGI KAMFRADGLL PASSKHIHEN AE 412 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004021; F:L-alanine:2-oxoglutarate aminotransferase activity; IDA:EcoCyc.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0030632; P:D-alanine biosynthetic process; IMP:UniProtKB.
 GO:0019272; P:L-alanine biosynthetic process from pyruvate; IMP:EcoCyc. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF00155; Aminotran_1_2 
SMART
  
PROSITE
 PS00105; AA_TRANSFER_CLASS_1 
PRINTS