| Tag | Content |
|---|
| CPLM ID | CPLM-000910 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 500 |
Protein Synonyms/Alias | Zinc finger protein with KRAB and SCAN domains 18 |
Gene Name | ZNF500 |
Gene Synonyms/Alias | KIAA0557; ZKSCAN18 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 158 | GIGGQFLKHQAEAQP | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 50 134 SCAN box.
DOMAIN 224 260 KRAB.
ZN_FING 325 347 C2H2-type 1.
ZN_FING 353 375 C2H2-type 2.
ZN_FING 381 403 C2H2-type 3.
ZN_FING 409 431 C2H2-type 4.
ZN_FING 437 459 C2H2-type 5. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 480 AA |
Protein Sequence | MATVPGLQPL PTLEQDLEQE EILIVKVEED FCLEEEPSVE TEDPSPETFR QLFRLFCYQE 60
VAGPREALSR LWELCCRWLR PELRTKEQIL ELLVLEQFLT VLPGEIQARV REQQPESGEE 120
AVVLVEGLQR KPRKHRQRGS ELLSDDEVPL GIGGQFLKHQ AEAQPEDLSL EEEARFSSQQ 180
PPAQLSHRPQ RGPLLWPERG PPAPRHQEMA SASPFLSAWS QVPVNLEDVA VYLSGEEPRC 240
MDPAQRDAPL ENEGPGIQLE DGGDGREDAP LRMEWYRVLS ARCQGPGHPL PGQRPAPVRG 300
LVRPDQPRGG PPPGRRASHG ADKPYTCPEC GKGFSKTSHL TKHQRTHTGE RPYKCLVCGK 360
GFSDRSNFST HQRVHTGEKP YPCPECGKRF SQSSSLVIHR RTHSGERPYA CTQCGKRFNN 420
SSHFSAHRRT HTGEKPYTCP ACGRGFRRGT DLHKHQRTHM GAGSLPTLQP VAPGGPGAKA 480 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0016032; P:viral reproduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |