CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005719
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kinesin-like protein KIP2 
Protein Synonyms/Alias
  
Gene Name
 KIP2 
Gene Synonyms/Alias
 YPL155C; P2581 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
124SRDHVGLKSPRYSQPacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Required for assembly of the mitotic spindle. 
Sequence Annotation
 DOMAIN 94 506 Kinesin-motor.
 NP_BIND 202 209 ATP (By similarity).  
Keyword
 ATP-binding; Cell cycle; Cell division; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Mitosis; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 706 AA 
Protein Sequence
MIQKMSPSLR RPSTRSSSGS SNIPQSPSVR STSSFSNLTR NSIRSTSNSG SQSISASSTR 60
SNSPLRSVSA KSDPFLHPGR IRIRRSDSIN NNSRKNDTYT GSITVTIRPK PRSVGTSRDH 120
VGLKSPRYSQ PRSNSHHGSN TFVRDPWFIT NDKTIVHEEI GEFKFDHVFA SHCTNLEVYE 180
RTSKPMIDKL LMGFNATIFA YGMTGSGKTF TMSGNEQELG LIPLSVSYLF TNIMEQSMNG 240
DKKFDVIISY LEIYNERIYD LLESGLEESG SRISTPSRLY MSKSNSNGLG VELKIRDDSQ 300
YGVKVIGLTE RRCESSEELL RWIAVGDKSR KIGETDYNAR SSRSHAIVLI RLTSTNVKNG 360
TSRSSTLSLC DLAGSERATG QQERRKEGSF INKSLLALGT VISKLSADKM NSVGSNIPSP 420
SASGSSSSSG NATNNGTSPS NHIPYRDSKL TRLLQPALSG DSIVTTICTV DTRNDAAAET 480
MNTLRFASRA KNVALHVSKK SIISNGNNDG DKDRTIELLR RQLEEQRRMI SELKNRSNIG 540
EPLTKSSNES TYKDIKATGN DGDPNLALMR AENRVLKYKL ENCEKLLDKD VVDLQDSEIM 600
EIVEMLPFEV GTLLETKFQG LESQIRQYRK YTQKLEDKIM ALEKSGHTAM SLTGCDGTEV 660
IELQKMLERK DKMIEALQSA KRLRDRALKP LINTQQSPHP VVDNDK 706 
Gene Ontology
 GO:0005881; C:cytoplasmic microtubule; IDA:SGD.
 GO:0005871; C:kinesin complex; TAS:SGD.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; TAS:SGD.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW.
 GO:0007026; P:negative regulation of microtubule depolymerization; IMP:SGD.
 GO:0030473; P:nuclear migration along microtubule; IMP:SGD. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.