UniProt Accession

 RL37A_HUMAN; P61513; P12751; Q6FGF5 

Genbank Protein ID

 L06499; X66699; L22154; AK289472; CR542152; AC073321; CH471063; BC000555; BC014262; BC016748; BC067789; BC082239 

Genbank Nucleotide ID

 AAA60280.1; CAA47244.1; BAF82161.1; CAG46949.1; AAY15078.1; EAW70569.1; AAH00555.2; AAH14262.1; AAH16748.1; AAH67789.1; AAH82239.1 

Protein Name

 60S ribosomal protein L37a 

Protein Synonyms/Alias

  

Gene Name

 RPL37A 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
13	KKVGIVGKYGTRYGA	acetylation	[1]
13	KKVGIVGKYGTRYGA	ubiquitination	[2, 3, 4, 5]
44	YTCSFCGKTKMKRRA	ubiquitination	[4]
87	KSAIRRLKELKDQ**	ubiquitination	[3]

Reference

 [1] Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.
 Morselli E, Mariño G, Bennetzen MV, Eisenberg T, Megalou E, Schroeder S, Cabrera S, Bénit P, Rustin P, Criollo A, Kepp O, Galluzzi L, Shen S, Malik SA, Maiuri MC, Horio Y, López-Otín C, Andersen JS, Tavernarakis N, Madeo F, Kroemer G.
 J Cell Biol. 2011 Feb 21;192(4):615-29. [PMID: 21339330]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 ZN_FING 39 60 C4-type.  

Keyword

 3D-structure; Complete proteome; Metal-binding; Reference proteome; Ribonucleoprotein; Ribosomal protein; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 92 AA 

Protein Sequence

Gene Ontology

 GO:0022625; C:cytosolic large ribosomal subunit; IDA:UniProtKB.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
 GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
 GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
 GO:0006414; P:translational elongation; TAS:Reactome.
 GO:0006413; P:translational initiation; TAS:Reactome.
 GO:0006415; P:translational termination; TAS:Reactome.
 GO:0019083; P:viral transcription; TAS:Reactome. 

Interpro

 IPR002674; Ribosomal_L37ae.
 IPR011331; Ribosomal_L37ae/L37e.
 IPR011332; Ribosomal_zn-bd_dom. 

Pfam

 PF01780; Ribosomal_L37ae 

SMART

  

PROSITE

  

PRINTS