CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032898
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serine/threonine-protein phosphatase 4 regulatory subunit 2 
Protein Synonyms/Alias
  
Gene Name
 PPP4R2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
11ERLQEALKDFEKRGKubiquitination[1]
15EALKDFEKRGKKEVCubiquitination[1]
52FKGYFIFKLEKVMDDubiquitination[1]
55YFIFKLEKVMDDFRTubiquitination[1, 2]
84YIPFDEMKERILKIVubiquitination[1, 3]
120RNYTGTDKFLRGVEKubiquitination[1, 3]
221EAEGHEVKRLRFD**acetylation[4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 226 AA 
Protein Sequence
MDVERLQEAL KDFEKRGKKE VCPVLDQFLC HVAKTGETMI QWSQFKGYFI FKLEKVMDDF 60
RTSAPEPRGP PNPNVEYIPF DEMKERILKI VTGFNGIPFT IQRLCELLTD PRRNYTGTDK 120
FLRGVEKNVM VVSCVYPSSE SNINGPGTPR PLNRPKVSLS APMTTNGLPE STDSKEANLQ 180
QNEEKNHSDS STSESEVSSV SPLKNKHPDE DAVEAEGHEV KRLRFD 226 
Gene Ontology
  
Interpro
 IPR015267; PPP4R2. 
Pfam
 PF09184; PPP4R2 
SMART
  
PROSITE
  
PRINTS