CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Pcdhga12 
Protein Synonyms/Alias
  
Gene Name
 Pcdhga12 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
910TLTNAAGKRDGKAPAubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity). 
Sequence Annotation
  
Keyword
 Calcium; Cell adhesion; Cell membrane; Complete proteome; Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 932 AA 
Protein Sequence
MIPMQRPEDC KGLVFLGVFF GMLWEAGSTQ IRYSVPEELE KGSRVGNISK DLGLEPRELA 60
ERGVRIVSRG RAQLFALNPR SGSLVTAGKI DREELCMGSI KCQLNLEILM EDIGKIYGVE 120
IEVRDINDNA PYFRESELEI KMSENAAAGM RFPLPHAWDP DIGKNSLQSY QLSPNAHFSL 180
EVQKGADGNK YPELVLESSL DREEKAAHLL VLTASDAGDP VRSGTARILV TVLDANDNAP 240
AFARSEYRVN VRENVAVGTQ LLLVNATDRD EGSNAEVIYS FRYVDDKAAK VFKLDSNLGT 300
ISTIGELNHE ESGFYEMEVQ ATDNAGFSAR AKVLVTVLDV NDNAPEVAIT SLNSPVPENS 360
PRGTLIALLN VNDQDSGENG QVICSIQENL PFKLEKSYGN YYSLLTDAVL DREQVPSYNI 420
TVTATDRGSP PLTTETHLSL NVADANDNPP IFLQASYWAY IQENNPRGAS IASVTAHDPD 480
SDKNAQVTYS LAEDTHQGVP LSSYVSINSD TGVLYALHSF DYEQFPDLQL QVIARDSGEP 540
PLSSNVSLSL FVLDQNDNTP EILYPTLPTD GSTGVELAPR SAEPGYLVTK VVAVDRDSGQ 600
NAWLSYRLLK ASEPGLFSVG LHTGEVSTAR ALMDRDALKQ NLVVSVQDHG QPPLSATVTL 660
TVAIADSIPD VLADLDNLES PTTSETSGLT LYLVVAVAAV SMVFLVFVLV LLALRLRRWH 720
SLRLLRAAGP GLADVAASRF VGVDGVQAFL QTYSHEVSLT AGSRKSHLIF PQPNYADTLI 780
SQESCEKTEP LLPSSDLVFS KDNHALNQHC PPNPGHRFTK TDSHMSSLSQ NGDETGTWPN 840
NQFDTEMLQA MILASASEAA DGSSTLGGGT GTMGLSARYG PQFTLQHVPD YRQNVYIPGS 900
NATLTNAAGK RDGKAPAGGN GNKKKSGKKE KK 932 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0007156; P:homophilic cell adhesion; IEA:InterPro. 
Interpro
 IPR002126; Cadherin.
 IPR015919; Cadherin-like.
 IPR020894; Cadherin_CS.
 IPR013164; Cadherin_N. 
Pfam
 PF00028; Cadherin
 PF08266; Cadherin_2 
SMART
 SM00112; CA 
PROSITE
 PS00232; CADHERIN_1
 PS50268; CADHERIN_2 
PRINTS
 PR00205; CADHERIN.