CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002772
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoglycerate kinase 
Protein Synonyms/Alias
  
Gene Name
 pgk 
Gene Synonyms/Alias
 TTHA0906 
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
67RPKGPDPKYSLAPVGacetylation[1]
122RFEPGEEKNDPELSAacetylation[1]
198GGAKVSDKIGVIESLacetylation[1]
244EDRLDLAKDLLGRAEacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841
Functional Description
  
Sequence Annotation
 NP_BIND 347 350 ATP (By similarity).
 REGION 19 21 Substrate binding (By similarity).
 REGION 57 60 Substrate binding (By similarity).
 BINDING 34 34 Substrate (By similarity).
 BINDING 115 115 Substrate (By similarity).
 BINDING 148 148 Substrate (By similarity).
 BINDING 198 198 ATP (By similarity).
 BINDING 289 289 ATP; via carbonyl oxygen (By similarity).
 BINDING 320 320 ATP (By similarity).  
Keyword
 3D-structure; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Glycolysis; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 390 AA 
Protein Sequence
MRTLLDLDPK GKRVLVRVDY NVPVQDGKVQ DETRILESLP TLRHLLAGGA SLVLLSHLGR 60
PKGPDPKYSL APVGEALRAH LPEARFAPFP PGSEEARREA EALRPGEVLL LENVRFEPGE 120
EKNDPELSAR YARLGEAFVL DAFGSAHRAH ASVVGVARLL PAYAGFLMEK EVRALSRLLK 180
DPERPYAVVL GGAKVSDKIG VIESLLPRID RLLIGGAMAF TFLKALGGEV GRSLVEEDRL 240
DLAKDLLGRA EALGVRVYLP EDVVAAERIE AGVETRVFPA RAIPVPYMGL DIGPKTREAF 300
ARALEGARTV FWNGPMGVFE VPPFDEGTLA VGQAIAALEG AFTVVGGGDS VAAVNRLGLK 360
ERFGHVSTGG GASLEFLEKG TLPGLEVLEG 390 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004618; F:phosphoglycerate kinase activity; IEA:HAMAP.
 GO:0006096; P:glycolysis; IEA:HAMAP. 
Interpro
 IPR001576; Phosphoglycerate_kinase.
 IPR015901; Phosphoglycerate_kinase_C.
 IPR015911; Phosphoglycerate_kinase_CS.
 IPR015824; Phosphoglycerate_kinase_N. 
Pfam
 PF00162; PGK 
SMART
  
PROSITE
 PS00111; PGLYCERATE_KINASE 
PRINTS
 PR00477; PHGLYCKINASE.