UniProt Accession

 YNG1_YEAST; Q08465; D6W2C7; O00025 

Genbank Protein ID

 Z70678; Z74972; AY557753; BK006948 

Genbank Nucleotide ID

 CAA94549.1; CAA99257.1; AAS56079.1; DAA10843.1 

Protein Name

 Protein YNG1 

Protein Synonyms/Alias

 ING1 homolog 1 

Gene Name

 YNG1 

Gene Synonyms/Alias

 YOR064C; YOR29-15 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
42	MQTIDLFKNEEDEPG	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Histone-binding component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation. YNG1 is required for the HAT activity of NuA3 but not for its integrity. Mediates the interaction of SAS3 with nucleosomes. 

Sequence Annotation

 ZN_FING 155 204 PHD-type; degenerate.
 BINDING 157 157 Histone H3K4me3 (By similarity).
 BINDING 168 168 Histone H3K4me3 (By similarity).
 BINDING 172 172 Histone H3K4me3 (By similarity).
 BINDING 180 180 Histone H3K4me3 (By similarity).  

Keyword

 3D-structure; Complete proteome; Metal-binding; Nucleus; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 219 AA 

Protein Sequence

Gene Ontology

 GO:0033100; C:NuA3 histone acetyltransferase complex; IDA:SGD.
 GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0016573; P:histone acetylation; IDA:SGD.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR013083; Znf_RING/FYVE/PHD. 

Pfam

 PF00628; PHD 

SMART

 SM00249; PHD 

PROSITE

 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 

PRINTS