CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002433
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein S100-A4 
Protein Synonyms/Alias
 Metastasin; Metastatic cell protein; PEL98; Placental calcium-binding protein; Protein 18A2; Protein Mts1; S100 calcium-binding protein A4 
Gene Name
 S100a4 
Gene Synonyms/Alias
 Capl; Mts1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
48ELPSFLGKRTDEAAFacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
  
Sequence Annotation
 DOMAIN 12 47 EF-hand 1.
 DOMAIN 50 85 EF-hand 2.
 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 35 35 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Calcium; Complete proteome; Direct protein sequencing; Metal-binding; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 101 AA 
Protein Sequence
MARPLEEALD VIVSTFHKYS GKEGDKFKLN KTELKELLTR ELPSFLGKRT DEAAFQKVMS 60
NLDSNRDNEV DFQEYCVFLS CIAMMCNEFF EGCPDKEPRK K 101 
Gene Ontology
 GO:0043005; C:neuron projection; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0005509; F:calcium ion binding; IDA:MGI.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR001751; S100/CaBP-9k_CS.
 IPR013787; S100_Ca-bd_sub. 
Pfam
 PF01023; S_100 
SMART
  
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00303; S100_CABP 
PRINTS