| Tag | Content |
|---|
| CPLM ID | CPLM-021327 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transmembrane protein 245 |
Protein Synonyms/Alias | Protein CG-2 |
Gene Name | TMEM245 |
Gene Synonyms/Alias | C9orf5 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 455 | KMIIWLEKMLDKIIS | ubiquitination | [1] | | 459 | WLEKMLDKIISIFII | ubiquitination | [1] | | 558 | NNTAVIEKQVLELWD | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | |
Sequence Annotation | MOD_RES 12 12 Phosphoserine (By similarity).
MOD_RES 16 16 Phosphoserine (By similarity).
MOD_RES 36 36 Phosphothreonine.
MOD_RES 332 332 Phosphoserine.
MOD_RES 334 334 Phosphothreonine.
CARBOHYD 210 210 N-linked (GlcNAc...) (Potential).
CARBOHYD 500 500 N-linked (GlcNAc...) (Potential).
CARBOHYD 551 551 N-linked (GlcNAc...).
CARBOHYD 575 575 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 911 AA |
Protein Sequence | MADGGGPKDA PSLRSSPGPA PRVPRAVGPS GGGGETPRTA ALALRFDKPI KQAFYNTGAV 60
LFVCLCCGAA VLVYFILEAF LRPLLWAVLC GTFLHPFKSS LTRLGRHWLQ RLHRAHTPIV 120
LAALLLPLCF VDYGVEALGE QALRRRRLLL LLGAGGPLLY GLYCLGSYLG VQVLLVHAAT 180
LICRGLDYFS SLWIWTLVVG YVLTVSFKWN ASTERYLRAV SIPVWIILLF HLASLAGSWR 240
IPVFLVIVFL MSVGTLYEKQ NGKESSGAEL PGQVISMAAS TLANLAISIT GYESSSEDQP 300
STQPAEAVDR GESAPTLSTS PSPSSPSPTS PSPTLGRRRP EIGTFLRKKK TSDIYFVSLV 360
WAIVVMQIWL NLWIVQLLPV PIAVWILKKL VIHFGVVDFL EKRYHVWWGI IESFLKERQG 420
ALAPWPIVGL GKFLLKVDSK LWHWLNKKMI IWLEKMLDKI ISIFIIFLLV IGTLLLALLL 480
TAKVHQESVH MIEVTSNLIN ETLANHPEWA NWLPEAQVVQ RALNSAANNV YQYGREWITH 540
KLHKILGDKV NNTAVIEKQV LELWDRLYHS WFVKNVTHSG RHKGQKLHVS RQNSWLGDIL 600
DWQDIVSFVH ENIETFLSIL ESLWIVMSRN VSLLFTTVTT LLTILFYSGT ALLNFVLSLI 660
IFLTTLFYLL SSSDEYYKPV KWVISLTPLS QPGPSSNIIG QSVEEAIRGV FDASLKMAGF 720
YGLYTWLTHT MFGINIVFIP SALAAILGAV PFLGTYWAAV PAVLDLWLTQ GLGCKAILLL 780
IFHLLPTYFV DTAIYSDISG GGHPYLTGLA VAGGAYYLGL EGAIIGPILL CILVVASNIY 840
SAMLVSPTNS VPTPNQTPWP AQPQRTFRDI SEDLKSSVG 879 |
Gene Ontology | GO:0016021; C:integral to membrane; NAS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |