CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010679
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 THUMP domain-containing protein 3 
Protein Synonyms/Alias
 GtROSA26asSor 
Gene Name
 Thumpd3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
142WQINTTFKKKKAKRRubiquitination[1]
371NISSLLTKSQIKDGKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 DOMAIN 171 287 THUMP.  
Keyword
 Alternative splicing; Complete proteome; Methyltransferase; Reference proteome; RNA-binding; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 505 AA 
Protein Sequence
MSCDTQEATR ECLGMNLDGN KEPVSLVESG VRSESEHLQV TIGATVPTGF EQTAAGEVRE 60
KLKSACRISK DRGKIYFDIA VESLAQVHCL RSVDNLFVVV QEFKDYQFKD TKEEVLRDFE 120
ELAGKLPWSD PLKVWQINTT FKKKKAKRRK ANQSAGKEKA DCGQGDKADE KDGKKKHASS 180
TSDSHILDYY ENPAIKEEIS TLVGDVLSSC KDETGQSLRE ETEPQVQKFR VTCNRAGEKH 240
CFTSNEAARD FGGAIQEYFK WKADMTNFDV EVLLNIHDNE VIVAIALTEE SLHRRNITHF 300
GPTTLRSTLA YGMLRLCEPK PTDVIVDPMC GTGAIPIEGA TEWSHCYHIA GDNNPLAVNR 360
AANNISSLLT KSQIKDGKTT WGLPIDAVQW DICNLPLRTA SVDIIVTDMP FGKRMGSKKR 420
NWNLYPACLR EMSRVCRPGT GRAVLLTQDK KCFTKALSGM GHVWRKVHVV WVNIGGLHAA 480
VYLLKRTAQA FVHPSDQDEG RDPPW 505 
Gene Ontology
 GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW. 
Interpro
 IPR000241; RNA_methylase_dom.
 IPR004114; THUMP. 
Pfam
 PF02926; THUMP
 PF01170; UPF0020 
SMART
 SM00981; THUMP 
PROSITE
 PS51165; THUMP
 PS01261; UPF0020 
PRINTS