CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018383
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Titin 
Protein Synonyms/Alias
 Connectin; Rhabdomyosarcoma antigen MU-RMS-40.14 
Gene Name
 TTN 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
2043DELLHWTKELTEEEKubiquitination[1]
2050KELTEEEKKALAEEGubiquitination[1]
3269ISGRPQPKISWYKEEubiquitination[1]
4941SVGELIVKEPAKIIEubiquitination[1]
4945LIVKEPAKIIERAELubiquitination[1]
8416CVGSIALKAPPRFVKubiquitination[1]
10506IEEPPPAKVPEAPKKubiquitination[1]
11464KEVVPEKKVPVPPPKubiquitination[2]
14371TGDRVKMKTLSAYAEubiquitination[1]
15135DLKWEPPKNDGGRPIubiquitination[2]
15149IQRYVIEKKERLGTRubiquitination[2]
15424DITKSSCKLTWEPPEubiquitination[1]
16243STITLDWKEPRSNGGubiquitination[1]
17653RPEDLEVKEVTKNTVacetylation[3]
19446SITLGWGKPVYDGGAubiquitination[1]
19465YVVEMRPKIADASPDubiquitination[1]
19841QITIKAGKKLRIEAHubiquitination[1]
22545VTKLKVTKLLKGNEYubiquitination[1]
22548LKVTKLLKGNEYIFRubiquitination[1]
23937VNRYDSGKYTLTLENacetylation[3]
23949LENSSGTKSAFVTVRacetylation[3]
26642PHYDGGAKITGYIVEubiquitination[1]
28031ISGYFLEKRDKKSLGmethylation[4]
28034YFLEKRDKKSLGWFKmethylation[4]
30001LDAAVGGKPEPKIIWubiquitination[2]
30005VGGKPEPKIIWTKGDubiquitination[2]
30291SISLAWTKPMYDGGTubiquitination[5]
30350RVAAVNVKGMSEYSEubiquitination[1]
33033IDDYLAMKRTEEERLubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786]
 [4] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510]
 [5] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
 Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase. 
Sequence Annotation
 DOMAIN 6 96 Ig-like 1.
 DOMAIN 104 192 Ig-like 2.
 REPEAT 417 462 Z-repeat 1.
 REPEAT 466 511 Z-repeat 2.
 REPEAT 512 554 Z-repeat 3.
 REPEAT 555 600 Z-repeat 4.
 REPEAT 601 646 Z-repeat 5.
 REPEAT 647 691 Z-repeat 6.
 REPEAT 692 740 Z-repeat 7.
 DOMAIN 943 1031 Ig-like 3.
 DOMAIN 1082 1172 Ig-like 4.
 DOMAIN 1291 1382 Ig-like 5.
 DOMAIN 1457 1546 Ig-like 6.
 DOMAIN 1556 1646 Ig-like 7.
 DOMAIN 1703 1793 Ig-like 8.
 DOMAIN 1841 1928 Ig-like 9.
 DOMAIN 2078 2167 Ig-like 10.
 REPEAT 2089 2122 TPR 1.
 DOMAIN 2171 2262 Ig-like 11.
 DOMAIN 2264 2354 Ig-like 12.
 DOMAIN 2353 2443 Ig-like 13.
 DOMAIN 2430 2529 Ig-like 14.
 DOMAIN 2620 2703 Ig-like 15.
 REPEAT 2804 2838 TPR 2.
 DOMAIN 2880 2965 Ig-like 16.
 DOMAIN 2968 3050 Ig-like 17.
 REPEAT 3022 3062 WD 1.
 DOMAIN 3058 3141 Ig-like 18.
 DOMAIN 3239 3327 Ig-like 19.
 DOMAIN 3344 3432 Ig-like 20.
 DOMAIN 3503 3586 Ig-like 21.
 DOMAIN 3621 3712 Ig-like 22.
 REPEAT 4168 4203 TPR 3.
 DOMAIN 4289 4376 Ig-like 23.
 DOMAIN 4383 4471 Ig-like 24.
 DOMAIN 4478 4566 Ig-like 25.
 DOMAIN 4571 4659 Ig-like 26.
 DOMAIN 4664 4753 Ig-like 27.
 DOMAIN 4758 4846 Ig-like 28.
 DOMAIN 4851 4936 Ig-like 29.
 REPEAT 4860 4904 Kelch 1.
 DOMAIN 4943 5032 Ig-like 30.
 DOMAIN 5040 5128 Ig-like 31.
 DOMAIN 5133 5221 Ig-like 32.
 REPEAT 5170 5203 TPR 4.
 DOMAIN 5225 5314 Ig-like 33.
 DOMAIN 5320 5408 Ig-like 34.
 DOMAIN 5413 5501 Ig-like 35.
 DOMAIN 5505 5594 Ig-like 36.
 DOMAIN 5602 5690 Ig-like 37.
 DOMAIN 5695 5783 Ig-like 38.
 DOMAIN 5788 5877 Ig-like 39.
 DOMAIN 5882 5970 Ig-like 40.
 DOMAIN 5975 6063 Ig-like 41.
 DOMAIN 6067 6156 Ig-like 42.
 DOMAIN 6164 6252 Ig-like 43.
 DOMAIN 6257 6347 Ig-like 44.
 DOMAIN 6350 6440 Ig-like 45.
 DOMAIN 6444 6534 Ig-like 46.
 REPEAT 6474 6507 TPR 5.
 DOMAIN 6537 6626 Ig-like 47.
 DOMAIN 6630 6721 Ig-like 48.
 REPEAT 6654 6692 WD 2.
 DOMAIN 6727 6815 Ig-like 49.
 DOMAIN 6820 6908 Ig-like 50.
 DOMAIN 6912 7001 Ig-like 51.
 DOMAIN 7005 7093 Ig-like 52.
 DOMAIN 7102 7190 Ig-like 53.
 DOMAIN 7198 7286 Ig-like 54.
 DOMAIN 7291 7380 Ig-like 55.
 DOMAIN 7385 7473 Ig-like 56.
 REPEAT 7415 7448 TPR 6.
 DOMAIN 7478 7567 Ig-like 57.
 DOMAIN 7571 7662 Ig-like 58.
 DOMAIN 7668 7756 Ig-like 59.
 DOMAIN 7761 7849 Ig-like 60.
 DOMAIN 7853 7942 Ig-like 61.
 DOMAIN 7946 8035 Ig-like 62.
 DOMAIN 8042 8133 Ig-like 63.
 DOMAIN 8138 8229 Ig-like 64.
 DOMAIN 8232 8321 Ig-like 65.
 DOMAIN 8326 8414 Ig-like 66.
 DOMAIN 8419 8508 Ig-like 67.
 DOMAIN 8512 8603 Ig-like 68.
 DOMAIN 8609 8697 Ig-like 69.
 DOMAIN 8702 8790 Ig-like 70.
 DOMAIN 8794 8883 Ig-like 71.
 DOMAIN 8888 8976 Ig-like 72.
 DOMAIN 8984 9074 Ig-like 73.
 DOMAIN 9079 9168 Ig-like 74.
 DOMAIN 9176 9265 Ig-like 75.
 REPEAT 9184 9221 TPR 7.
 DOMAIN 9272 9361 Ig-like 76.
 DOMAIN 9366 9470 Ig-like 77.
 DOMAIN 9660 9755 Ig-like 78.
 REPEAT 9701 9734 TPR 8.
 DOMAIN 9760 9851 Ig-like 79.
 REPEAT 10031 10064 TPR 9.
 REPEAT 10041 10087 Kelch 2.
 REPEAT 10216 10242 PEVK 1.
 REPEAT 10244 10270 PEVK 2.
 REPEAT 10272 10298 PEVK 3.
 REPEAT 10300 10326 PEVK 4.
 REPEAT 10327 10353 PEVK 5.
 REPEAT 10355 10381 PEVK 6.
 REPEAT 10508 10534 PEVK 7.
 REPEAT 10536 10562 PEVK 8.
 REPEAT 10592 10618 PEVK 9.
 REPEAT 10878 10904 PEVK 10.
 REPEAT 10906 10930 PEVK 11.
 REPEAT 10932 10958 PEVK 12.
 REPEAT 10960 10986 PEVK 13.
 REPEAT 10987 11014 PEVK 14.
 REPEAT 11363 11396 PEVK 15.
 REPEAT 11397 11421 PEVK 16.
 REPEAT 11453 11479 PEVK 17.
 REPEAT 11481 11507 PEVK 18.
 REPEAT 11509 11535 PEVK 19.
 REPEAT 11537 11563 PEVK 20.
 REPEAT 11565 11591 PEVK 21.
 REPEAT 11657 11683 PEVK 22.
 REPEAT 11703 11729 PEVK 23.
 REPEAT 11745 11771 PEVK 24.
 REPEAT 11775 11801 PEVK 25.
 REPEAT 11836 11862 PEVK 26.
 REPEAT 11864 11890 PEVK 27.
 REPEAT 11893 11919 PEVK 28.
 REPEAT 11929 11955 PEVK 29.
 REPEAT 11966 11992 PEVK 30.
 REPEAT 11996 12022 PEVK 31.
 DOMAIN 12041 12133 Ig-like 80.
 DOMAIN 12138 12222 Ig-like 81.
 DOMAIN 12233 12318 Ig-like 82.
 DOMAIN 12499 12584 Ig-like 83.
 DOMAIN 12590 12672 Ig-like 84.
 DOMAIN 12766 12850 Ig-like 85.
 DOMAIN 12945 13032 Ig-like 86.
 REPEAT 12955 12988 TPR 10.
 DOMAIN 13120 13206 Ig-like 87.
 DOMAIN 13210 13295 Ig-like 88.
 DOMAIN 13299 13384 Ig-like 89.
 DOMAIN 13388 13478 Ig-like 90.
 REPEAT 13391 13432 WD 3.
 REPEAT 13443 13485 WD 4.
 DOMAIN 13479 13562 Ig-like 91.
 DOMAIN 13565 13655 Ig-like 92.
 DOMAIN 13659 13748 Ig-like 93.
 REPEAT 13714 13753 WD 5.
 DOMAIN 13749 13833 Ig-like 94.
 DOMAIN 13927 14012 Ig-like 95.
 DOMAIN 14017 14109 Fibronectin type-III 1.
 REPEAT 14084 14136 RCC1 1.
 DOMAIN 14118 14210 Fibronectin type-III 2.
 REPEAT 14185 14238 RCC1 2.
 DOMAIN 14219 14311 Fibronectin type-III 3.
 DOMAIN 14415 14506 Fibronectin type-III 4.
 DOMAIN 14515 14606 Fibronectin type-III 5.
 DOMAIN 14615 14708 Ig-like 96.
 DOMAIN 14711 14802 Fibronectin type-III 6.
 DOMAIN 14809 14902 Fibronectin type-III 7.
 REPEAT 14828 14876 Kelch 3.
 DOMAIN 14910 15002 Fibronectin type-III 8.
 REPEAT 14986 15036 Kelch 4.
 DOMAIN 15010 15104 Fibronectin type-III 9.
 REPEAT 15077 15130 RCC1 3.
 DOMAIN 15111 15203 Fibronectin type-III 10.
 DOMAIN 15211 15305 Fibronectin type-III 11.
 DOMAIN 15314 15402 Ig-like 97.
 DOMAIN 15407 15500 Fibronectin type-III 12.
 DOMAIN 15506 15599 Fibronectin type-III 13.
 REPEAT 15574 15630 RCC1 4.
 DOMAIN 15608 15724 Ig-like 98.
 DOMAIN 15729 15822 Fibronectin type-III 14.
 DOMAIN 15829 15923 Fibronectin type-III 15.
 DOMAIN 15929 16021 Fibronectin type-III 16.
 DOMAIN 16029 16119 Ig-like 99.
 DOMAIN 16124 16214 Fibronectin type-III 17.
 REPEAT 16134 16180 WD 6.
 DOMAIN 16221 16314 Fibronectin type-III 18.
 DOMAIN 16322 16420 Ig-like 100.
 DOMAIN 16425 16518 Fibronectin type-III 19.
 DOMAIN 16526 16623 Fibronectin type-III 20.
 DOMAIN 16631 16726 Fibronectin type-III 21.
 DOMAIN 16727 16834 Ig-like 101.
 DOMAIN 16839 16930 Fibronectin type-III 22.
 DOMAIN 16938 17036 Fibronectin type-III 23.
 DOMAIN 17044 17139 Ig-like 102.
 DOMAIN 17144 17236 Fibronectin type-III 24.
 DOMAIN 17244 17343 Fibronectin type-III 25.
 DOMAIN 17348 17440 Fibronectin type-III 26.
 DOMAIN 17449 17536 Ig-like 103.
 DOMAIN 17543 17637 Fibronectin type-III 27.
 DOMAIN 17644 17736 Fibronectin type-III 28.
 REPEAT 17711 17769 RCC1 5.
 DOMAIN 17745 17834 Ig-like 104.
 DOMAIN 17839 17931 Fibronectin type-III 29.
 REPEAT 17930 17969 WD 7.
 DOMAIN 17939 18031 Fibronectin type-III 30.
 REPEAT 18006 18055 RCC1 6.
 DOMAIN 18040 18134 Fibronectin type-III 31.
 DOMAIN 18143 18228 Ig-like 105.
 DOMAIN 18237 18330 Fibronectin type-III 32.
 REPEAT 18258 18303 Kelch 5.
 REPEAT 18303 18358 RCC1 7.
 DOMAIN 18336 18427 Fibronectin type-III 33.
 DOMAIN 18435 18526 Ig-like 106.
 DOMAIN 18531 18623 Fibronectin type-III 34.
 REPEAT 18553 18598 Kelch 6.
 DOMAIN 18630 18722 Fibronectin type-III 35.
 DOMAIN 18730 18824 Fibronectin type-III 36.
 DOMAIN 18833 18924 Ig-like 107.
 DOMAIN 18929 19019 Fibronectin type-III 37.
 DOMAIN 19028 19121 Fibronectin type-III 38.
 DOMAIN 19128 19219 Ig-like 108.
 DOMAIN 19224 19315 Fibronectin type-III 39.
 REPEAT 19290 19346 RCC1 8.
 DOMAIN 19323 19415 Fibronectin type-III 40.
 REPEAT 19389 19452 RCC1 9.
 DOMAIN 19423 19522 Fibronectin type-III 41.
 DOMAIN 19531 19617 Ig-like 109.
 DOMAIN 19626 19717 Fibronectin type-III 42.
 REPEAT 19647 19692 Kelch 7.
 DOMAIN 19726 19818 Fibronectin type-III 43.
 DOMAIN 19826 19914 Ig-like 110.
 DOMAIN 19919 20011 Fibronectin type-III 44.
 DOMAIN 20019 20111 Fibronectin type-III 45.
 DOMAIN 20116 20211 Fibronectin type-III 46.
 DOMAIN 20220 20311 Ig-like 111.
 DOMAIN 20316 20407 Fibronectin type-III 47.
 DOMAIN 20414 20507 Fibronectin type-III 48.
 DOMAIN 20515 20609 Fibronectin type-III 49.
 DOMAIN 20714 20805 Fibronectin type-III 50.
 DOMAIN 20811 20900 Fibronectin type-III 51.
 REPEAT 20833 20876 Kelch 8.
 DOMAIN 20893 20996 Ig-like 112.
 DOMAIN 21003 21097 Fibronectin type-III 52.
 REPEAT 21069 21125 RCC1 10.
 DOMAIN 21103 21195 Fibronectin type-III 53.
 DOMAIN 21200 21294 Fibronectin type-III 54.
 REPEAT 21222 21267 Kelch 9.
 DOMAIN 21303 21395 Ig-like 113.
 DOMAIN 21400 21491 Fibronectin type-III 55.
 DOMAIN 21498 21591 Fibronectin type-III 56.
 REPEAT 21565 21620 RCC1 11.
 DOMAIN 21599 21693 Fibronectin type-III 57.
 DOMAIN 21701 21793 Ig-like 114.
 DOMAIN 21795 21886 Fibronectin type-III 58.
 REPEAT 21860 21910 RCC1 12.
 DOMAIN 21892 21982 Fibronectin type-III 59.
 DOMAIN 21990 22083 Ig-like 115.
 DOMAIN 22086 22178 Fibronectin type-III 60.
 DOMAIN 22186 22278 Fibronectin type-III 61.
 DOMAIN 22283 22377 Fibronectin type-III 62.
 REPEAT 22306 22350 Kelch 10.
 DOMAIN 22386 22477 Ig-like 116.
 DOMAIN 22482 22574 Fibronectin type-III 63.
 DOMAIN 22581 22674 Fibronectin type-III 64.
 DOMAIN 22683 22776 Fibronectin type-III 65.
 DOMAIN 22785 22874 Ig-like 117.
 DOMAIN 22879 22970 Fibronectin type-III 66.
 DOMAIN 22976 23066 Fibronectin type-III 67.
 REPEAT 23041 23091 RCC1 13.
 DOMAIN 23075 23163 Ig-like 118.
 DOMAIN 23168 23262 Fibronectin type-III 68.
 DOMAIN 23268 23360 Fibronectin type-III 69.
 DOMAIN 23365 23459 Fibronectin type-III 70.
 DOMAIN 23468 23555 Ig-like 119.
 DOMAIN 23564 23656 Fibronectin type-III 71.
 REPEAT 23651 23694 WD 8.
 DOMAIN 23664 23756 Fibronectin type-III 72.
 DOMAIN 23765 23858 Fibronectin type-III 73.
 DOMAIN 23867 23954 Ig-like 120.
 DOMAIN 23961 24052 Fibronectin type-III 74.
 REPEAT 24027 24076 RCC1 14.
 DOMAIN 24058 24148 Fibronectin type-III 75.
 REPEAT 24079 24124 Kelch 11.
 DOMAIN 24157 24241 Ig-like 121.
 DOMAIN 24250 24344 Fibronectin type-III 76.
 REPEAT 24261 24307 WD 9.
 DOMAIN 24350 24442 Fibronectin type-III 77.
 DOMAIN 24447 24541 Fibronectin type-III 78.
 DOMAIN 24550 24641 Ig-like 122.
 DOMAIN 24646 24738 Fibronectin type-III 79.
 DOMAIN 24746 24838 Fibronectin type-III 80.
 DOMAIN 24847 24940 Fibronectin type-III 81.
 REPEAT 24868 24916 Kelch 12.
 DOMAIN 24949 25038 Ig-like 123.
 DOMAIN 25043 25134 Fibronectin type-III 82.
 DOMAIN 25139 25230 Fibronectin type-III 83.
 DOMAIN 25239 25325 Ig-like 124.
 DOMAIN 25332 25424 Fibronectin type-III 84.
 REPEAT 25343 25389 WD 10.
 REPEAT 25419 25462 WD 11.
 DOMAIN 25432 25524 Fibronectin type-III 85.
 DOMAIN 25529 25623 Fibronectin type-III 86.
 DOMAIN 25632 25722 Ig-like 125.
 DOMAIN 25729 25821 Fibronectin type-III 87.
 DOMAIN 25828 25921 Fibronectin type-III 88.
 DOMAIN 25929 26023 Fibronectin type-III 89.
 REPEAT 25951 25997 Kelch 13.
 DOMAIN 26032 26121 Ig-like 126.
 DOMAIN 26126 26217 Fibronectin type-III 90.
 DOMAIN 26222 26313 Fibronectin type-III 91.
 REPEAT 26244 26289 Kelch 14.
 DOMAIN 26322 26410 Ig-like 127.
 DOMAIN 26415 26506 Fibronectin type-III 92.
 REPEAT 26501 26544 WD 12.
 DOMAIN 26513 26607 Fibronectin type-III 93.
 DOMAIN 26611 26705 Fibronectin type-III 94.
 DOMAIN 26714 26801 Ig-like 128.
 DOMAIN 26810 26902 Fibronectin type-III 95.
 DOMAIN 26910 27002 Fibronectin type-III 96.
 DOMAIN 27011 27102 Fibronectin type-III 97.
 REPEAT 27077 27127 RCC1 15.
 DOMAIN 27101 27196 Ig-like 129.
 DOMAIN 27205 27296 Fibronectin type-III 98.
 REPEAT 27271 27320 RCC1 16.
 DOMAIN 27302 27392 Fibronectin type-III 99.
 REPEAT 27323 27368 Kelch 15.
 DOMAIN 27497 27589 Fibronectin type-III 100.
 DOMAIN 27597 27689 Fibronectin type-III 101.
 DOMAIN 27694 27788 Fibronectin type-III 102.
 DOMAIN 27797 27888 Ig-like 130.
 DOMAIN 27893 27985 Fibronectin type-III 103.
 DOMAIN 27993 28088 Fibronectin type-III 104.
 REPEAT 28062 28095 TPR 11.
 DOMAIN 28093 28187 Fibronectin type-III 105.
 DOMAIN 28196 28286 Ig-like 131.
 DOMAIN 28293 28384 Fibronectin type-III 106.
 DOMAIN 28390 28480 Fibronectin type-III 107.
 DOMAIN 28488 28577 Ig-like 132.
 DOMAIN 28584 28676 Fibronectin type-III 108.
 REPEAT 28606 28651 Kelch 16.
 REPEAT 28671 28714 WD 13.
 DOMAIN 28684 28776 Fibronectin type-III 109.
 DOMAIN 28781 28874 Fibronectin type-III 110.
 DOMAIN 28882 28974 Ig-like 133.
 DOMAIN 28979 29071 Fibronectin type-III 111.
 REPEAT 29046 29101 RCC1 17.
 DOMAIN 29079 29171 Fibronectin type-III 112.
 DOMAIN 29180 29273 Fibronectin type-III 113.
 DOMAIN 29282 29367 Ig-like 134.
 DOMAIN 29376 29467 Fibronectin type-III 114.
 DOMAIN 29473 29563 Fibronectin type-III 115.
 DOMAIN 29568 29663 Ig-like 135.
 DOMAIN 29668 29760 Fibronectin type-III 116.
 DOMAIN 29767 29860 Fibronectin type-III 117.
 DOMAIN 29865 29962 Fibronectin type-III 118.
 DOMAIN 29971 30059 Ig-like 136.
 DOMAIN 30068 30159 Fibronectin type-III 119.
 DOMAIN 30167 30260 Fibronectin type-III 120.
 DOMAIN 30269 30365 Fibronectin type-III 121.
 DOMAIN 30371 30460 Ig-like 137.
 DOMAIN 30465 30556 Fibronectin type-III 122.
 DOMAIN 30562 30654 Fibronectin type-III 123.
 DOMAIN 30663 30754 Ig-like 138.
 DOMAIN 30759 30853 Fibronectin type-III 124.
 DOMAIN 30859 30951 Fibronectin type-III 125.
 REPEAT 30880 30925 Kelch 17.
 DOMAIN 30959 31052 Fibronectin type-III 126.
 DOMAIN 31061 31150 Ig-like 139.
 DOMAIN 31155 31247 Fibronectin type-III 127.
 DOMAIN 31256 31351 Fibronectin type-III 128.
 DOMAIN 31358 31450 Fibronectin type-III 129.
 DOMAIN 31460 31548 Ig-like 140.
 DOMAIN 31650 31743 Fibronectin type-III 130.
 REPEAT 31739 31782 WD 14.
 DOMAIN 31752 31846 Fibronectin type-III 131.
 DOMAIN 31855 31945 Ig-like 141.
 REPEAT 31892 31937 WD 15.
 DOMAIN 31955 32046 Ig-like 142.
 DOMAIN 32049 32139 Fibronectin type-III 132.
 REPEAT 32070 32115 Kelch 18.
 DOMAIN 32178 32432 Protein kinase.
 DOMAIN 32496 32584 Ig-like 143.
 REPEAT 32503 32549 Kelch 19.
 DOMAIN 32617 32710 Ig-like 144.
 DOMAIN 32722 32811 Ig-like 145.
 REPEAT 32927 32960 TPR 12.
 REPEAT 33235 33268 TPR 13.
 DOMAIN 33301 33391 Ig-like 146.
 DOMAIN 33488 33576 Ig-like 147.
 REPEAT 33518 33551 TPR 14.
 DOMAIN 33645 33732 Ig-like 148.
 DOMAIN 33779 33867 Ig-like 149.
 DOMAIN 33963 34052 Ig-like 150.
 DOMAIN 34061 34149 Ig-like 151.
 DOMAIN 34256 34344 Ig-like 152.
 NP_BIND 32184 32192 ATP (By similarity).
 REGION 253 341 ZIS1.
 REGION 1410 1440 ZIS5.
 ACT_SITE 32298 32298 Proton acceptor (By similarity).
 BINDING 32207 32207 ATP (By similarity).
 MOD_RES 263 263 Phosphoserine (By similarity).
 MOD_RES 265 265 Phosphoserine (By similarity).
 MOD_RES 267 267 Phosphothreonine (By similarity).
 MOD_RES 4065 4065 Phosphoserine.
 MOD_RES 4068 4068 Phosphoserine.
 MOD_RES 6920 6920 Phosphoserine (By similarity).
 MOD_RES 8490 8490 Phosphotyrosine.
 MOD_RES 9122 9122 Phosphoserine (By similarity).
 MOD_RES 9203 9203 Phosphoserine.
 MOD_RES 9207 9207 Phosphothreonine.
 MOD_RES 11503 11503 Phosphoserine (By similarity).
 MOD_RES 12007 12007 Phosphothreonine (By similarity).
 MOD_RES 12009 12009 Phosphoserine (By similarity).
 MOD_RES 12022 12022 Phosphoserine (By similarity).
 MOD_RES 22525 22525 Phosphoserine.
 MOD_RES 22534 22534 Phosphoserine.
 MOD_RES 30443 30443 Phosphothreonine (By similarity).
 MOD_RES 32341 32341 Phosphotyrosine.
 MOD_RES 33245 33245 Phosphoserine (By similarity).
 MOD_RES 33247 33247 Phosphoserine (By similarity).
 MOD_RES 33602 33602 Phosphoserine (By similarity).
 MOD_RES 33614 33614 Phosphoserine (By similarity).
 MOD_RES 33938 33938 Phosphoserine.
 MOD_RES 33942 33942 Phosphoserine.
 DISULFID 964 1015 By similarity.
 DISULFID 1724 1777 By similarity.
 DISULFID 2109 2134
 DISULFID 2196 2246 By similarity.
 DISULFID 3259 3311 By similarity.
 DISULFID 4404 4455 By similarity.
 DISULFID 4499 4550 By similarity.
 DISULFID 4592 4643 By similarity.
 DISULFID 4686 4737 By similarity.
 DISULFID 4779 4830 By similarity.
 DISULFID 5061 5112 By similarity.
 DISULFID 5248 5299 By similarity.
 DISULFID 5623 5674 By similarity.
 DISULFID 5810 5861 By similarity.
 DISULFID 5903 5954 By similarity.
 DISULFID 6185 6236 By similarity.
 DISULFID 6372 6423 By similarity.
 DISULFID 6465 6516 By similarity.
 DISULFID 6748 6799 By similarity.
 DISULFID 7027 7078 By similarity.
 DISULFID 7123 7174 By similarity.
 DISULFID 7219 7270 By similarity.
 DISULFID 7313 7364 By similarity.
 DISULFID 7406 7457 By similarity.
 DISULFID 7689 7740 By similarity.
 DISULFID 7968 8019 By similarity.
 DISULFID 8064 8115 By similarity.
 DISULFID 8160 8211 By similarity.
 DISULFID 8254 8305 By similarity.
 DISULFID 8347 8398 By similarity.
 DISULFID 8630 8681 By similarity.
 DISULFID 8909 8960 By similarity.
 DISULFID 9005 9056 By similarity.
 DISULFID 9101 9152 By similarity.
 DISULFID 9294 9345 By similarity.
 DISULFID 9693 9743 By similarity.
 DISULFID 12067 12117 By similarity.
 DISULFID 12611 12660 By similarity.
 DISULFID 12966 13016 By similarity.
 DISULFID 13233 13283 By similarity.
 DISULFID 13322 13372 By similarity.
 DISULFID 13411 13461 By similarity.
 DISULFID 13771 13821 By similarity.
 DISULFID 31481 31532 By similarity.
 DISULFID 32516 32568 By similarity.
 DISULFID 33664 33718 By similarity.
 CROSSLNK 10718 10718 Glycyl lysine isopeptide (Lys-Gly)
 CROSSLNK 10733 10733 Glycyl lysine isopeptide (Lys-Gly)
 CROSSLNK 10740 10740 Glycyl lysine isopeptide (Lys-Gly)
 CROSSLNK 29566 29566 Glycyl lysine isopeptide (Lys-Gly)
 CROSSLNK 30146 30146 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 3D-structure; Alternative splicing; ATP-binding; Calcium; Calmodulin-binding; Cardiomyopathy; Coiled coil; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Disulfide bond; Immunoglobulin domain; Isopeptide bond; Kelch repeat; Kinase; Limb-girdle muscular dystrophy; Magnesium; Metal-binding; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Serine/threonine-protein kinase; TPR repeat; Transferase; Ubl conjugation; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 34350 AA 
Protein Sequence
MTTQAPTFTQ PLQSVVVLEG STATFEAHIS GFPVPEVSWF RDGQVISTST LPGVQISFSD 60
GRAKLTIPAV TKANSGRYSL KATNGSGQAT STAELLVKAE TAPPNFVQRL QSMTVRQGSQ 120
VRLQVRVTGI PTPVVKFYRD GAEIQSSLDF QISQEGDLYS LLIAEAYPED SGTYSVNATN 180
SVGRATSTAE LLVQGEEEVP AKKTKTIVST AQISESRQTR IEKKIEAHFD ARSIATVEMV 240
IDGAAGQQLP HKTPPRIPPK PKSRSPTPPS IAAKAQLARQ QSPSPIRHSP SPVRHVRAPT 300
PSPVRSVSPA ARISTSPIRS VRSPLLMRKT QASTVATGPE VPPPWKQEGY VASSSEAEMR 360
ETTLTTSTQI RTEERWEGRY GVQEQVTISG AAGAAASVSA SASYAAEAVA TGAKEVKQDA 420
DKSAAVATVV AAVDMARVRE PVISAVEQTA QRTTTTAVHI QPAQEQVRKE AEKTAVTKVV 480
VAADKAKEQE LKSRTKEVIT TKQEQMHVTH EQIRKETEKT FVPKVVISAA KAKEQETRIS 540
EEITKKQKQV TQEAIRQETE ITAASMVVVA TAKSTKLETV PGAQEETTTQ QDQMHLSYEK 600
IMKETRKTVV PKVIVATPKV KEQDLVSRGR EGITTKREQV QITQEKMRKE AEKTALSTIA 660
VATAKAKEQE TILRTRETMA TRQEQIQVTH GKVDVGKKAE AVATVVAAVD QARVREPREP 720
GHLEESYAQQ TTLEYGYKER ISAAKVAEPP QRPASEPHVV PKAVKPRVIQ APSETHIKTT 780
DQKGMHISSQ IKKTTDLTTE RLVHVDKRPR TASPHFTVSK ISVPKTEHGY EASIAGSAIA 840
TLQKELSATS SAQKITKSVK APTVKPSETR VRAEPTPLPQ FPFADTPDTY KSEAGVEVKK 900
EVGVSITGTT VREERFEVLH GREAKVTETA RVPAPVEIPV TPPTLVSGLK NVTVIEGESV 960
TLECHISGYP SPTVTWYRED YQIESSIDFQ ITFQSGIARL MIREAFAEDS GRFTCSAVNE 1020
AGTVSTSCYL AVQVSEEFEK ETTAVTEKFT TEEKRFVESR DVVMTDTSLT EEQAGPGEPA 1080
APYFITKPVV QKLVEGGSVV FGCQVGGNPK PHVYWKKSGV PLTTGYRYKV SYNKQTGECK 1140
LVISMTFADD AGEYTIVVRN KHGETSASAS LLEEADYELL MKSQQEMLYQ TQVTAFVQEP 1200
KVGETAPGFV YSEYEKEYEK EQALIRKKMA KDTVVVRTYV EDQEFHISSF EERLIKEIEY 1260
RIIKTTLEEL LEEDGEEKMA VDISESEAVE SGFDSRIKNY RILEGMGVTF HCKMSGYPLP 1320
KIAWYKDGKR IKHGERYQMD FLQDGRASLR IPVVLPEDEG IYTAFASNIK GNAICSGKLY 1380
VEPAAPLGAP TYIPTLEPVS RIRSLSPRSV SRSPIRMSPA RMSPARMSPA RMSPARMSPG 1440
RRLEETDESQ LERLYKPVFV LKPVSFKCLE GQTARFDLKV VGRPMPETFW FHDGQQIVND 1500
YTHKVVIKED GTQSLIIVPA TPSDSGEWTV VAQNRAGRSS ISVILTVEAV EHQVKPMFVE 1560
KLKNVNIKEG SRLEMKVRAT GNPNPDIVWL KNSDIIVPHK YPKIRIEGTK GEAALKIDST 1620
VSQDSAWYTA TAINKAGRDT TRCKVNVEVE FAEPEPERKL IIPRGTYRAK EIAAPELEPL 1680
HLRYGQEQWE EGDLYDKEKQ QKPFFKKKLT SLRLKRFGPA HFECRLTPIG DPTMVVEWLH 1740
DGKPLEAANR LRMINEFGYC SLDYGVAYSR DSGIITCRAT NKYGTDHTSA TLIVKDEKSL 1800
VEESQLPEGR KGLQRIEELE RMAHEGALTG VTTDQKEKQK PDIVLYPEPV RVLEGETARF 1860
RCRVTGYPQP KVNWYLNGQL IRKSKRFRVR YDGIHYLDIV DCKSYDTGEV KVTAENPEGV 1920
IEHKVKLEIQ QREDFRSVLR RAPEPRPEFH VHEPGKLQFE VQKVDRPVDT TETKEVVKLK 1980
RAERITHEKV PEESEELRSK FKRRTEEGYY EAITAVELKS RKKDESYEEL LRKTKDELLH 2040
WTKELTEEEK KALAEEGKIT IPTFKPDKIE LSPSMEAPKI FERIQSQTVG QGSDAHFRVR 2100
VVGKPDPECE WYKNGVKIER SDRIYWYWPE DNVCELVIRD VTAEDSASIM VKAINIAGET 2160
SSHAFLLVQA KQLITFTQEL QDVVAKEKDT MATFECETSE PFVKVKWYKD GMEVHEGDKY 2220
RMHSDRKVHF LSILTIDTSD AEDYSCVLVE DENVKTTAKL IVEGAVVEFV KELQDIEVPE 2280
SYSGELECIV SPENIEGKWY HNDVELKSNG KYTITSRRGR QNLTVKDVTK EDQGEYSFVI 2340
DGKKTTCKLK MKPRPIAILQ GLSDQKVCEG DIVQLEVKVS LESVEGVWMK DGQEVQPSDR 2400
VHIVIDKQSH MLLIEDMTKE DAGNYSFTIP ALGLSTSGRV SVYSVDVITP LKDVNVIEGT 2460
KAVLECKVSV PDVTSVKWYL NDEQIKPDDR VQAIVKGTKQ RLVINRTHAS DEGPYKLIVG 2520
RVETNCNLSV EKIKIIRGLR DLTCTETQNV VFEVELSHSG IDVLWNFKDK EIKPSSKYKI 2580
EAHGKIYKLT VLNMMKDDEG KYTFYAGENM TSGKLTVAGG AISKPLTDQT VAESQEAVFE 2640
CEVANPDSKG EWLRDGKHLP LTNNIRSESD GHKRRLIIAA TKLDDIGEYT YKVATSKTSA 2700
KLKVEAVKIK KTLKNLTVTE TQDAVFTVEL THPNVKGVQW IKNGVVLESN EKYAISVKGT 2760
IYSLRIKNCA IVDESVYGFR LGRLGASARL HVETVKIIKK PKDVTALENA TVAFEVSVSH 2820
DTVPVKWFHK SVEIKPSDKH RLVSERKVHK LMLQNISPSD AGEYTAVVGQ LECKAKLFVE 2880
TLHITKTMKN IEVPETKTAS FECEVSHFNV PSMWLKNGVE IEMSEKFKIV VQGKLHQLII 2940
MNTSTEDSAE YTFVCGNDQV SATLTVTPIM ITSMLKDINA EEKDTITFEV TVNYEGISYK 3000
WLKNGVEIKS TDKCQMRTKK LTHSLNIRNV HFGDAADYTF VAGKATSTAT LYVEARHIEF 3060
RKHIKDIKVL EKKRAMFECE VSEPDITVQW MKDDQELQIT DRIKIQKEKY VHRLLIPSTR 3120
MSDAGKYTVV AGGNVSTAKL FVEGRDVRIR SIKKEVQVIE KQRAVVEFEV NEDDVDAHWY 3180
KDGIEINFQV QERHKYVVER RIHRMFISET RQSDAGEYTF VAGRNRSSVT LYVNAPEPPQ 3240
VLQELQPVTV QSGKPARFCA VISGRPQPKI SWYKEEQLLS TGFKCKFLHD GQEYTLLLIE 3300
AFPEDAAVYT CEAKNDYGVA TTSASLSVEV PEVVSPDQEM PVYPPAIITP LQDTVTSEGQ 3360
PARFQCRVSG TDLKVSWYSK DKKIKPSRFF RMTQFEDTYQ LEIAEAYPED EGTYTFVASN 3420
AVGQVSSTAN LSLEAPESIL HERIEQEIEM EMKEFSSSFL SAEEEGLHSA ELQLSKINET 3480
LELLSESPVY PTKFDSEKEG TGPIFIKEVS NADISMGDVA TLSVTVIGIP KPKIQWFFNG 3540
VLLTPSADYK FVFDGDDHSL IILFTKLEDE GEYTCMASND YGKTICSAYL KINSKGEGHK 3600
DTETESAVAK SLEKLGGPCP PHFLKELKPI RCAQGLPAIF EYTVVGEPAP TVTWFKENKQ 3660
LCTSVYYTII HNPNGSGTFI VNDPQREDSG LYICKAENML GESTCAAELL VLLEDTDMTD 3720
TPCKAKSTPE APEDFPQTPL KGPAVEALDS EQEIATFVKD TILKAALITE ENQQLSYEHI 3780
AKANELSSQL PLGAQELQSI LEQDKLTPES TREFLCINGS IHFQPLKEPS PNLQLQIVQS 3840
QKTFSKEGIL MPEEPETQAV LSDTEKIFPS AMSIEQINSL TVEPLKTLLA EPEGNYPQSS 3900
IEPPMHSYLT SVAEEVLSPK EKTVSDTNRE QRVTLQKQEA QSALILSQSL AEGHVESLQS 3960
PDVMISQVNY EPLVPSEHSC TEGGKILIES ANPLENAGQD SAVRIEEGKS LRFPLALEEK 4020
QVLLKEEHSD NVVMPPDQII ESKREPVAIK KVQEVQGRDL LSKESLLSGI PEEQRLNLKI 4080
QICRALQAAV ASEQPGLFSE WLRNIEKVEV EAVNITQEPR HIMCMYLVTS AKSVTEEVTI 4140
IIEDVDPQMA NLKMELRDAL CAIIYEEIDI LTAEGPRIQQ GAKTSLQEEM DSFSGSQKVE 4200
PITEPEVESK YLISTEEVSY FNVQSRVKYL DATPVTKGVA SAVVSDEKQD ESLKPSEEKE 4260
ESSSESGTEE VATVKIQEAE GGLIKEDGPM IHTPLVDTVS EEGDIVHLTT SITNAKEVNW 4320
YFENKLVPSD EKFKCLQDQN TYTLVIDKVN TEDHQGEYVC EALNDSGKTA TSAKLTVVKR 4380
AAPVIKRKIE PLEVALGHLA KFTCEIQSAP NVRFQWFKAG REIYESDKCS IRSSKYISSL 4440
EILRTQVVDC GEYTCKASNE YGSVSCTATL TVTEAYPPTF LSRPKSLTTF VGKAAKFICT 4500
VTGTPVIETI WQKDGAALSP SPNWRISDAE NKHILELSNL TIQDRGVYSC KASNKFGADI 4560
CQAELIIIDK PHFIKELEPV QSAINKKVHL ECQVDEDRKV TVTWSKDGQK LPPGKDYKIC 4620
FEDKIATLEI PLAKLKDSGT YVCTASNEAG SSSCSATVTV REPPSFVKKV DPSYLMLPGE 4680
SARLHCKLKG SPVIQVTWFK NNKELSESNT VRMYFVNSEA ILDITDVKVE DSGSYSCEAV 4740
NDVGSDSCST EIVIKEPPSF IKTLEPADIV RGTNALLQCE VSGTGPFEIS WFKDKKQIRS 4800
SKKYRLFSQK SLVCLEIFSF NSADVGEYEC VVANEVGKCG CMATHLLKEP PTFVKKVDDL 4860
IALGGQTVTL QAAVRGSEPI SVTWMKGQEV IREDGKIKMS FSNGVAVLII PDVQISFGGK 4920
YTCLAENEAG SQTSVGELIV KEPAKIIERA ELIQVTAGDP ATLEYTVAGT PELKPKWYKD 4980
GRPLVASKKY RISFKNNVAQ LKFYSAELHD SGQYTFEISN EVGSSSCETT FTVLDRDIAP 5040
FFTKPLRNVD SVVNGTCRLD CKIAGSLPMR VSWFKDGKEI AASDRYRIAF VEGTASLEII 5100
RVDMNDAGNF TCRATNSVGS KDSSGALIVQ EPPSFVTKPG SKDVLPGSAV CLKSTFQGST 5160
PLTIRWFKGN KELVSGGSCY ITKEALESSL ELYLVKTSDS GTYTCKVSNV AGGVECSANL 5220
FVKEPATFVE KLEPSQLLKK GDATQLACKV TGTPPIKITW FANDREIKES SKHRMSFVES 5280
TAVLRLTDVG IEDSGEYMCE AQNEAGSDHC SSIVIVKESP YFTKEFKPIE VLKEYDVMLL 5340
AEVAGTPPFE ITWFKDNTIL RSGRKYKTFI QDHLVSLQIL KFVAADAGEY QCRVTNEVGS 5400
SICSARVTLR EPPSFIKKIE STSSLRGGTA AFQATLKGSL PITVTWLKDS DEITEDDNIR 5460
MTFENNVASL YLSGIEVKHD GKYVCQAKND AGIQRCSALL SVKEPATITE EAVSIDVTQG 5520
DPATLQVKFS GTKEITAKWF KDGQELTLGS KYKISVTDTV SILKIISTEK KDSGEYTFEV 5580
QNDVGRSSCK ARINVLDLII PPSFTKKLKK MDSIKGSFID LECIVAGSHP ISIQWFKDDQ 5640
EISASEKYKF SFHDNTAFLE ISQLEGTDSG TYTCSATNKA GHNQCSGHLT VKEPPYFVEK 5700
PQSQDVNPNT RVQLKALVGG TAPMTIKWFK DNKELHSGAA RSVWKDDTST SLELFAAKAT 5760
DSGTYICQLS NDVGTATSKA TLFVKEPPQF IKKPSPVLVL RNGQSTTFEC QITGTPKIRV 5820
SWYLDGNEIT AIQKHGISFI DGLATFQISG ARVENSGTYV CEARNDAGTA SCSIELKVKE 5880
PPTFIRELKP VEVVKYSDVE LECEVTGTPP FEVTWLKNNR EIRSSKKYTL TDRVSVFNLH 5940
ITKCDPSDTG EYQCIVSNEG GSCSCSTRVA LKEPPSFIKK IENTTTVLKS SATFQSTVAG 6000
SPPISITWLK DDQILDEDDN VYISFVDSVA TLQIRSVDNG HSGRYTCQAK NESGVERCYA 6060
FLLVQEPAQI VEKAKSVDVT EKDPMTLECV VAGTPELKVK WLKDGKQIVP SRYFSMSFEN 6120
NVASFRIQSV MKQDSGQYTF KVENDFGSSS CDAYLRVLDQ NIPPSFTKKL TKMDKVLGSS 6180
IHMECKVSGS LPISAQWFKD GKEISTSAKY RLVCHERSVS LEVNNLELED TANYTCKVSN 6240
VAGDDACSGI LTVKEPPSFL VKPGRQQAIP DSTVEFKAIL KGTPPFKIKW FKDDVELVSG 6300
PKCFIGLEGS TSFLNLYSVD ASKTGQYTCH VTNDVGSDSC TTMLLVTEPP KFVKKLEASK 6360
IVKAGDSSRL ECKIAGSPEI RVVWFRNEHE LPASDKYRMT FIDSVAVIQM NNLSTEDSGD 6420
FICEAQNPAG STSCSTKVIV KEPPVFSSFP PIVETLKNAE VSLECELSGT PPFEVVWYKD 6480
KRQLRSSKKY KIASKNFHTS IHILNVDTSD IGEYHCKAQN EVGSDTCVCT VKLKEPPRFV 6540
SKLNSLTVVA GEPAELQASI EGAQPIFVQW LKEKEEVIRE SENIRITFVE NVATLQFAKA 6600
EPANAGKYIC QIKNDGGMRE NMATLMVLEP AVIVEKAGPM TVTVGETCTL ECKVAGTPEL 6660
SVEWYKDGKL LTSSQKHKFS FYNKISSLRI LSVERQDAGT YTFQVQNNVG KSSCTAVVDV 6720
SDRAVPPSFT RRLKNTGGVL GASCILECKV AGSSPISVAW FHEKTKIVSG AKYQTTFSDN 6780
VCTLQLNSLD SSDMGNYTCV AANVAGSDEC RAVLTVQEPP SFVKEPEPLE VLPGKNVTFT 6840
SVIRGTPPFK VNWFRGAREL VKGDRCNIYF EDTVAELELF NIDISQSGEY TCVVSNNAGQ 6900
ASCTTRLFVK EPAAFLKRLS DHSVEPGKSI ILESTYTGTL PISVTWKKDG FNITTSEKCN 6960
IVTTEKTCIL EILNSTKRDA GQYSCEIENE AGRDVCGALV STLEPPYFVT ELEPLEAAVG 7020
DSVSLQCQVA GTPEITVSWY KGDTKLRPTP EYRTYFTNNV ATLVFNKVNI NDSGEYTCKA 7080
ENSIGTASSK TVFRIQERQL PPSFARQLKD IEQTVGLPVT LTCRLNGSAP IQVCWYRDGV 7140
LLRDDENLQT SFVDNVATLK ILQTDLSHSG QYSCSASNPL GTASSSARLT AREPKKSPFF 7200
DIKPVSIDVI AGESADFECH VTGAQPMRIT WSKDNKEIRP GGNYTITCVG NTPHLRILKV 7260
GKGDSGQYTC QATNDVGKDM CSAQLSVKEP PKFVKKLEAS KVAKQGESIQ LECKISGSPE 7320
IKVSWFRNDS ELHESWKYNM SFINSVALLT INEASAEDSG DYICEAHNGV GDASCSTALT 7380
VKAPPVFTQK PSPVGALKGS DVILQCEISG TPPFEVVWVK DRKQVRNSKK FKITSKHFDT 7440
SLHILNLEAS DVGEYHCKAT NEVGSDTCSC SVKFKEPPRF VKKLSDTSTL IGDAVELRAI 7500
VEGFQPISVV WLKDRGEVIR ESENTRISFI DNIATLQLGS PEASNSGKYI CQIKNDAGMR 7560
ECSAVLTVLE PARIIEKPEP MTVTTGNPFA LECVVTGTPE LSAKWFKDGR ELSADSKHHI 7620
TFINKVASLK IPCAEMSDKG LYSFEVKNSV GKSNCTVSVH VSDRIVPPSF IRKLKDVNAI 7680
LGASVVLECR VSGSAPISVG WFQDGNEIVS GPKCQSSFSE NVCTLNLSLL EPSDTGIYTC 7740
VAANVAGSDE CSAVLTVQEP PSFEQTPDSV EVLPGMSLTF TSVIRGTPPF KVKWFKGSRE 7800
LVPGESCNIS LEDFVTELEL FEVQPLESGD YSCLVTNDAG SASCTTHLFV KEPATFVKRL 7860
ADFSVETGSP IVLEATYTGT PPISVSWIKD EYLISQSERC SITMTEKSTI LEILESTIED 7920
YAQYSCLIEN EAGQDICEAL VSVLEPPYFI EPLEHVEAVI GEPATLQCKV DGTPEIRISW 7980
YKEHTKLRSA PAYKMQFKNN VASLVINKVD HSDVGEYSCK ADNSVGAVAS SAVLVIKARK 8040
LPPFFARKLK DVHETLGFPV AFECRINGSE PLQVSWYKDG VLLKDDANLQ TSFVHNVATL 8100
QILQTDQSHI GQYNCSASNP LGTASSSAKL ILSEHEVPPF FDLKPVSVDL ALGESGTFKC 8160
HVTGTAPIKI TWAKDNREIR PGGNYKMTLV ENTATLTVLK VGKGDAGQYT CYASNIAGKD 8220
SCSAQLGVQE PPRFIKKLEP SRIVKQDEFT RYECKIGGSP EIKVLWYKDE TEIQESSKFR 8280
MSFVDSVAVL EMHNLSVEDS GDYTCEAHNA AGSASSSTSL KVKEPPIFRK KPHPIETLKG 8340
ADVHLECELQ GTPPFHVSWY KDKRELRSGK KYKIMSENFL TSIHILNVDA ADIGEYQCKA 8400
TNDVGSDTCV GSIALKAPPR FVKKLSDIST VVGKEVQLQT TIEGAEPISV VWFKDKGEIV 8460
RESDNIWISY SENIATLQFS RVEPANAGKY TCQIKNDAGM QECFATLSVL EPATIVEKPE 8520
SIKVTTGDTC TLECTVAGTP ELSTKWFKDG KELTSDNKYK ISFFNKVSGL KIINVAPSDS 8580
GVYSFEVQNP VGKDSCTASL QVSDRTVPPS FTRKLKETNG LSGSSVVMEC KVYGSPPISV 8640
SWFHEGNEIS SGRKYQTTLT DNTCALTVNM LEESDSGDYT CIATNMAGSD ECSAPLTVRE 8700
PPSFVQKPDP MDVLTGTNVT FTSIVKGTPP FSVSWFKGSS ELVPGDRCNV SLEDSVAELE 8760
LFDVDTSQSG EYTCIVSNEA GKASCTTHLY IKAPAKFVKR LNDYSIEKGK PLILEGTFTG 8820
TPPISVTWKK NGINVTPSQR CNITTTEKSA ILEIPSSTVE DAGQYNCYIE NASGKDSCSA 8880
QILILEPPYF VKQLEPVKVS VGDSASLQCQ LAGTPEIGVS WYKGDTKLRP TTTYKMHFRN 8940
NVATLVFNQV DINDSGEYIC KAENSVGEVS ASTFLTVQEQ KLPPSFSRQL RDVQETVGLP 9000
VVFDCAISGS EPISVSWYKD GKPLKDSPNV QTSFLDNTAT LNIFKTDRSL AGQYSCTATN 9060
PIGSASSSAR LILTEGKNPP FFDIRLAPVD AVVGESADFE CHVTGTQPIK VSWAKDSREI 9120
RSGGKYQISY LENSAHLTVL KVDKGDSGQY TCYAVNEVGK DSCTAQLNIK ERLIPPSFTK 9180
RLSETVEETE GNSFKLEGRV AGSQPITVAW YKNNIEIQPT SNCEITFKNN TLVLQVRKAG 9240
MNDAGLYTCK VSNDAGSALC TSSIVIKEPK KPPVFDQHLT PVTVSEGEYV QLSCHVQGSE 9300
PIRIQWLKAG REIKPSDRCS FSFASGTAVL ELRDVAKADS GDYVCKASNV AGSDTTKSKV 9360
TIKDKPAVAP ATKKAAVDGR LFFVSEPQSI RVVEKTTATF IAKVGGDPIP NVKWTKGKWR 9420
QLNQGGRVFI HQKGDEAKLE IRDTTKTDSG LYRCVAFNEH GEIESNVNLQ VDERKKQEKI 9480
EGDLRAMLKK TPILKKGAGE EEEIDIMELL KNVDPKEYEK YARMYGITDF RGLLQAFELL 9540
KQSQEEETHR LEIEEIERSE RDEKEFEELV SFIQQRLSQT EPVTLIKDIE NQTVLKDNDA 9600
VFEIDIKINY PEIKLSWYKG TEKLEPSDKF EISIDGDRHT LRVKNCQLKD QGNYRLVCGP 9660
HIASAKLTVI EPAWERHLQD VTLKEGQTCT MTCQFSVPNV KSEWFRNGRI LKPQGRHKTE 9720
VEHKVHKLTI ADVRAEDQGQ YTCKYEDLET SAELRIEAEP IQFTKRIQNI VVSEHQSATF 9780
ECEVSFDDAI VTWYKGPTEL TESQKYNFRN DGRCHYMTIH NVTPDDEGVY SVIARLEPRG 9840
EARSTAELYL TTKEIKLELK PPDIPDSRVP IPTMPIRAVP PEEIPPVVAP PIPLLLPTPE 9900
EKKPPPKRIE VTKKAVKKDA KKVVAKPKEM TPREEIVKKP PPPTTLIPAK APEIIDVSSK 9960
AEEVKIMTIT RKKEVQKEKE AVYEKKQAVH KEKRVFIESF EEPYDELEVE PYTEPFEQPY 10020
YEEPDEDYEE IKVEAKKEVH EEWEEDFEEG QEYYEREEGY DEGEEEWEEA YQEREVIQVQ 10080
KEVYEESHER KVPAKVPEKK APPPPKVIKK PVIEKIEKTS RRMEEEKVQV TKVPEVSKKI 10140
VPQKPSRTPV QEEVIEVKVP AVHTKKMVIS EEKMFFASHT EEEVSVTVPE VQKEIVTEEK 10200
IHVAISKRVE PPPKVPELPE KPAPEEVAPV PIPKKVEPPA PKVPEVPKKP VPEEKKPVPV 10260
PKKEPAAPPK VPEVPKKPVP EEKIPVPVAK KKEAPPAKVP EVQKGVVTEE KITIVTQREE 10320
SPPPAVPEIP KKKVPEERKP VPRKEEEVPP PPKVPALPKK PVPEEKVAVP VPVAKKAPPP 10380
RAEVSKKTVV EEKRFVAEEK LSFAVPQRVE VTRHEVSAEE EWSYSEEEEG VSISVYREEE 10440
REEEEEAEVT EYEVMEEPEE YVVEEKLHII SKRVEAEPAE VTERQEKKIV LKPKIPAKIE 10500
EPPPAKVPEA PKKIVPEKKV PAPVPKKEKV PPPKVPEEPK KPVPEKKVPP KVIKMEEPLP 10560
AKVTERHMQI TQEEKVLVAV TKKEAPPKAR VPEEPKRAVP EEKVLKLKPK REEEPPAKVT 10620
EFRKRVVKEE KVSIEAPKRE PQPIKEVTIM EEKERAYTLE EEAVSVQREE EYEEYEEYDY 10680
KEFEEYEPTE EYDQYEEYEE REYERYEEHE EYITEPEKPI PVKPVPEEPV PTKPKAPPAK 10740
VLKKAVPEEK VPVPIPKKLK PPPPKVPEEP KKVFEEKIRI SITKREKEQV TEPAAKVPMK 10800
PKRVVAEEKV PVPRKEVAPP VRVPEVPKEL EPEEVAFEEE VVTHVEEYLV EEEEEYIHEE 10860
EEFITEEEVV PVIPVKVPEV PRKPVPEEKK PVPVPKKKEA PPAKVPEVPK KPEEKVPVLI 10920
PKKEKPPPAK VPEVPKKPVP EEKVPVPVPK KVEAPPAKVP EVPKKPVPEK KVPVPAPKKV 10980
EAPPAKVPEV PKKLIPEEKK PTPVPKKVEA PPPKVPKKRE PVPVPVALPQ EEEVLFEEEI 11040
VPEEEVLPEE EEVLPEEEEV LPEEEEVLPE EEEIPPEEEE VPPEEEYVPE EEEFVPEEEV 11100
LPEVKPKVPV PAPVPEIKKK VTEKKVVIPK KEEAPPAKVP EVPKKVEEKR IILPKEEEVL 11160
PVEVTEEPEE EPISEEEIPE EPPSIEEVEE VAPPRVPEVI KKAVPEAPTP VPKKVEAPPA 11220
KVSKKIPEEK VPVPVQKKEA PPAKVPEVPK KVPEKKVLVP KKEAVPPAKG RTVLEEKVSV 11280
AFRQEVVVKE RLELEVVEAE VEEIPEEEEF HEVEEYFEEG EFHEVEEFIK LEQHRVEEEH 11340
RVEKVHRVIE VFEAEEVEVF EKPKAPPKGP EISEKIIPPK KPPTKVVPRK EPPAKVPEVP 11400
KKIVVEEKVR VPEEPRVPPT KVPEVLPPKE VVPEKKVPVP PAKKPEAPPP KVPEAPKEVV 11460
PEKKVPVPPP KKPEVPPTKV PEVPKAAVPE KKVPEAIPPK PESPPPEVPE APKEVVPEKK 11520
VPAAPPKKPE VTPVKVPEAP KEVVPEKKVP VPPPKKPEVP PTKVPEVPKV AVPEKKVPEA 11580
IPPKPESPPP EVFEEPEEVA LEEPPAEVVE EPEPAAPPQV TVPPKKPVPE KKAPAVVAKK 11640
PELPPVKVPE VPKEVVPEKK VPLVVPKKPE APPAKVPEVP KEVVPEKKVA VPKKPEVPPA 11700
KVPEVPKKPV LEEKPAVPVP ERAESPPPEV YEEPEEIAPE EEIAPEEEKP VPVAEEEEPE 11760
VPPPAVPEEP KKIIPEKKVP VIKKPEAPPP KEPEPEKVIE KPKLKPRPPP PPPAPPKEDV 11820
KEKIFQLKAI PKKKVPEKPQ VPEKVELTPL KVPGGEKKVR KLLPERKPEP KEEVVLKSVL 11880
RKRPEEEEPK VEPKKLEKVK KPAVPEPPPP KPVEEVEVPT VTKRERKIPE PTKVPEIKPA 11940
IPLPAPEPKP KPEAEVKTIK PPPVEPEPTP IAAPVTVPVV GKKAEAKAPK EEAAKPKGPI 12000
KGVPKKTPSP IEAERRKLRP GSGGEKPPDE APFTYQLKAV PLKFVKEIKD IILTESEFVG 12060
SSAIFECLVS PSTAITTWMK DGSNIRESPK HRFIADGKDR KLHIIDVQLS DAGEYTCVLR 12120
LGNKEKTSTA KLVVEELPVR FVKTLEEEVT VVKGQPLYLS CELNKERDVV WRKDGKIVVE 12180
KPGRIVPGVI GLMRALTIND ADDTDAGTYT VTVENANNLE CSSCVKVVEV IRDWLVKPIR 12240
DQHVKPKGTA IFACDIAKDT PNIKWFKGYD EIPAEPNDKT EILRDGNHLY LKIKNAMPED 12300
IAEYAVEIEG KRYPAKLTLG EREVELLKPI EDVTIYEKES ASFDAEISEA DIPGQWKLKG 12360
ELLRPSPTCE IKAEGGKRFL TLHKVKLDQA GEVLYQALNA ITTAILTVKE IELDFAVPLK 12420
DVTVPERRQA RFECVLTREA NVIWSKGPDI IKSSDKFDII ADGKKHILVI NDSQFDDEGV 12480
YTAEVEGKKT SARLFVTGIR LKFMSPLEDQ TVKEGETATF VCELSHEKMH VVWFKNDAKL 12540
HTSRTVLISS EGKTHKLEMK EVTLDDISQI KAQVKELSST AQLKVLEADP YFTVKLHDKT 12600
AVEKDEITLK CEVSKDVPVK WFKDGEEIVP SPKYSIKADG LRRILKIKKA DLKDKGEYVC 12660
DCGTDKTKAN VTVEARLIKV EKPLYGVEVF VGETAHFEIE LSEPDVHGQW KLKGQPLTAS 12720
PDCEIIEDGK KHILILHNCQ LGMTGEVSFQ AANAKSAANL KVKELPLIFI TPLSDVKVFE 12780
KDEAKFECEV SREPKTFRWL KGTQEITGDD RFELIKDGTK HSMVIKSAAF EDEAKYMFEA 12840
EDKHTSGKLI IEGIRLKFLT PLKDVTAKEK ESAVFTVELS HDNIRVKWFK NDQRLHTTRS 12900
VSMQDEGKTH SITFKDLSID DTSQIRVEAM GMSSEAKLTV LEGDPYFTGK LQDYTGVEKD 12960
EVILQCEISK ADAPVKWFKD GKEIKPSKNA VIKADGKKRM LILKKALKSD IGQYTCDCGT 13020
DKTSGKLDIE DREIKLVRPL HSVEVMETET ARFETEISED DIHANWKLKG EALLQTPDCE 13080
IKEEGKIHSL VLHNCRLDQT GGVDFQAANV KSSAHLRVKP RVIGLLRPLK DVTVTAGETA 13140
TFDCELSYED IPVEWYLKGK KLEPSDKVVP RSEGKVHTLT LRDVKLEDAG EVQLTAKDFK 13200
THANLFVKEP PVEFTKPLED QTVEEGATAV LECEVSRENA KVKWFKNGTE ILKSKKYEIV 13260
ADGRVRKLVI HDCTPEDIKT YTCDAKDFKT SCNLNVVPPH VEFLRPLTDL QVREKEMARF 13320
ECELSRENAK VKWFKDGAEI KKGKKYDIIS KGAVRILVIN KCLLDDEAEY SCEVRTARTS 13380
GMLTVLEEEA VFTKNLANIE VSETDTIKLV CEVSKPGAEV IWYKGDEEII ETGRYEILTE 13440
GRKRILVIQN AHLEDAGNYN CRLPSSRTDG KVKVHELAAE FISKPQNLEI LEGEKAEFVC 13500
SISKESFPVQ WKRDDKTLES GDKYDVIADG KKRVLVVKDA TLQDMGTYVV MVGAARAAAH 13560
LTVIEKLRIV VPLKDTRVKE QQEVVFNCEV NTEGAKAKWF RNEEAIFDSS KYIILQKDLV 13620
YTLRIRDAHL DDQANYNVSL TNHRGENVKS AANLIVEEED LRIVEPLKDI ETMEKKSVTF 13680
WCKVNRLNVT LKWTKNGEEV PFDNRVSYRV DKYKHMLTIK DCGFPDEGEY IVTAGQDKSV 13740
AELLIIEAPT EFVEHLEDQT VTEFDDAVFS CQLSREKANV KWYRNGREIK EGKKYKFEKD 13800
GSIHRLIIKD CRLDDECEYA CGVEDRKSRA RLFVEEIPVE IIRPPQDILE APGADVVFLA 13860
ELNKDKVEVQ WLRNNMVVVQ GDKHQMMSEG KIHRLQICDI KPRDQGEYRF IAKDKEARAK 13920
LELAAAPKIK TADQDLVVDV GKPLTMVVPY DAYPKAEAEW FKENEPLSTK TIDTTAEQTS 13980
FRILEAKKGD KGRYKIVLQN KHGKAEGFIN LKVIDVPGPV RNLEVTETFD GEVSLAWEEP 14040
LTDGGSKIIG YVVERRDIKR KTWVLATDRA ESCEFTVTGL QKGGVEYLFR VSARNRVGTG 14100
EPVETDNPVE ARSKYDVPGP PLNVTITDVN RFGVSLTWEP PEYDGGAEIT NYVIELRDKT 14160
SIRWDTAMTV RAEDLSATVT DVVEGQEYSF RVRAQNRIGV GKPSAATPFV KVADPIERPS 14220
PPVNLTSSDQ TQSSVQLKWE PPLKDGGSPI LGYIIERCEE GKDNWIRCNM KLVPELTYKV 14280
TGLEKGNKYL YRVSAENKAG VSDPSEILGP LTADDAFVEP TMDLSAFKDG LEVIVPNPIT 14340
ILVPSTGYPR PTATWCFGDK VLETGDRVKM KTLSAYAELV ISPSERSDKG IYTLKLENRV 14400
KTISGEIDVN VIARPSAPKE LKFGDITKDS VHLTWEPPDD DGGSPLTGYV VEKREVSRKT 14460
WTKVMDFVTD LEFTVPDLVQ GKEYLFKVCA RNKCGPGEPA YVDEPVNMST PATVPDPPEN 14520
VKWRDRTANS IFLTWDPPKN DGGSRIKGYI VERCPRGSDK WVACGEPVAE TKMEVTGLEE 14580
GKWYAYRVKA LNRQGASKPS RPTEEIQAVD TQEAPEIFLD VKLLAGLTVK AGTKIELPAT 14640
VTGKPEPKIT WTKADMILKQ DKRITIENVP KKSTVTIVDS KRSDTGTYII EAVNVCGRAT 14700
AVVEVNVLDK PGPPAAFDIT DVTNESCLLT WNPPRDDGGS KITNYVVERR ATDSEVWHKL 14760
SSTVKDTNFK ATKLIPNKEY IFRVAAENMY GVGEPVQASP ITAKYQFDPP GPPTRLEPSD 14820
ITKDAVTLTW CEPDDDGGSP ITGYWVERLD PDTDKWVRCN KMPVKDTTYR VKGLTNKKKY 14880
RFRVLAENLA GPGKPSKSTE PILIKDPIDP PWPPGKPTVK DVGKTSVRLN WTKPEHDGGA 14940
KIESYVIEML KTGTDEWVRV AEGVPTTQHL LPGLMEGQEY SFRVRAVNKA GESEPSEPSD 15000
PVLCREKLYP PSPPRWLEVI NITKNTADLK WTVPEKDGGS PITNYIVEKR DVRRKGWQTV 15060
DTTVKDTKCT VTPLTEGSLY VFRVAAENAI GQSDYTEIED SVLAKDTFTT PGPPYALAVV 15120
DVTKRHVDLK WEPPKNDGGR PIQRYVIEKK ERLGTRWVKA GKTAGPDCNF RVTDVIEGTE 15180
VQFQVRAENE AGVGHPSEPT EILSIEDPTS PPSPPLDLHV TDAGRKHIAI AWKPPEKNGG 15240
SPIIGYHVEM CPVGTEKWMR VNSRPIKDLK FKVEEGVVPD KEYVLRVRAV NAIGVSEPSE 15300
ISENVVAKDP DCKPTIDLET HDIIVIEGEK LSIPVPFRAV PVPTVSWHKD GKEVKASDRL 15360
TMKNDHISAH LEVPKSVRAD AGIYTITLEN KLGSATASIN VKVIGLPGPC KDIKASDITK 15420
SSCKLTWEPP EFDGGTPILH YVLERREAGR RTYIPVMSGE NKLSWTVKDL IPNGEYFFRV 15480
KAVNKVGGGE YIELKNPVIA QDPKQPPDPP VDVEVHNPTA EAMTITWKPP LYDGGSKIMG 15540
YIIEKIAKGE ERWKRCNEHL VPILTYTAKG LEEGKEYQFR VRAENAAGIS EPSRATPPTK 15600
AVDPIDAPKV ILRTSLEVKR GDEIALDASI SGSPYPTITW IKDENVIVPE EIKKRAAPLV 15660
RRRKGEVQEE EPFVLPLTQR LSIDNSKKGE SQLRVRDSLR PDHGLYMIKV ENDHGIAKAP 15720
CTVSVLDTPG PPINFVFEDI RKTSVLCKWE PPLDDGGSEI INYTLEKKDK TKPDSEWIVV 15780
TSTLRHCKYS VTKLIEGKEY LFRVRAENRF GPGPPCVSKP LVAKDPFGPP DAPDKPIVED 15840
VTSNSMLVKW NEPKDNGSPI LGYWLEKREV NSTHWSRVNK SLLNALKANV DGLLEGLTYV 15900
FRVCAENAAG PGKFSPPSDP KTAHDPISPP GPPIPRVTDT SSTTIELEWE PPAFNGGGEI 15960
VGYFVDKQLV GTNEWSRCTE KMIKVRQYTV KEIREGADYK LRVSAVNAAG EGPPGETQPV 16020
TVAEPQEPPA VELDVSVKGG IQIMAGKTLR IPAVVTGRPV PTKVWTKEEG ELDKDRVVID 16080
NVGTKSELII KDALRKDHGR YVITATNSCG SKFAAARVEV FDVPGPVLDL KPVVTNRKMC 16140
LLNWSDPEDD GGSEITGFII ERKDAKMHTW RQPIETERSK CDITGLLEGQ EYKFRVIAKN 16200
KFGCGPPVEI GPILAVDPLG PPTSPERLTY TERTKSTITL DWKEPRSNGG SPIQGYIIEK 16260
RRHDKPDFER VNKRLCPTTS FLVENLDEHQ MYEFRVKAVN EIGESEPSLP LNVVIQDDEV 16320
PPTIKLRLSV RGDTIKVKAG EPVHIPADVT GLPMPKIEWS KNETVIEKPT DALQITKEEV 16380
SRSEAKTELS IPKAVREDKG TYTVTASNRL GSVFRNVHVE VYDRPSPPRN LAVTDIKAES 16440
CYLTWDAPLD NGGSEITHYV IDKRDASRKK AEWEEVTNTA VEKRYGIWKL IPNGQYEFRV 16500
RAVNKYGISD ECKSDKVVIQ DPYRLPGPPG KPKVLARTKG SMLVSWTPPL DNGGSPITGY 16560
WLEKREEGSP YWSRVSRAPI TKVGLKGVEF NVPRLLEGVK YQFRAMAINA AGIGPPSEPS 16620
DPEVAGDPIF PPGPPSCPEV KDKTKSSISL GWKPPAKDGG SPIKGYIVEM QEEGTTDWKR 16680
VNEPDKLITT CECVVPNLKE LRKYRFRVKA VNEAGESEPS DTTGEIPATD IQEEPEVFID 16740
IGAQDCLVCK AGSQIRIPAV IKGRPTPKSS WEFDGKAKKA MKDGVHDIPE DAQLETAENS 16800
SVIIIPECKR SHTGKYSITA KNKAGQKTAN CRVKVMDVPG PPKDLKVSDI TRGSCRLSWK 16860
MPDDDGGDRI KGYVIEKRTI DGKAWTKVNP DCGSTTFVVP DLLSEQQYFF RVRAENRFGI 16920
GPPVETIQRT TARDPIYPPD PPIKLKIGLI TKNTVHLSWK PPKNDGGSPV THYIVECLAW 16980
DPTGTKKEAW RQCNKRDVEE LQFTVEDLVE GGEYEFRVKA VNAAGVSKPS ATVGPVTVKD 17040
QTCPPSIDLK EFMEVEEGTN VNIVAKIKGV PFPTLTWFKA PPKKPDNKEP VLYDTHVNKL 17100
VVDDTCTLVI PQSRRSDTGL YTITAVNNLG TASKEMRLNV LGRPGPPVGP IKFESVSADQ 17160
MTLSWFPPKD DGGSKITNYV IEKREANRKT WVHVSSEPKE CTYTIPKLLE GHEYVFRIMA 17220
QNKYGIGEPL DSEPETARNL FSVPGAPDKP TVSSVTRNSM TVNWEEPEYD GGSPVTGYWL 17280
EMKDTTSKRW KRVNRDPIKA MTLGVSYKVT GLIEGSDYQF RVYAINAAGV GPASLPSDPA 17340
TARDPIAPPG PPFPKVTDWT KSSADLEWSP PLKDGGSKVT GYIVEYKEEG KEEWEKGKDK 17400
EVRGTKLVVT GLKEGAFYKF RVRAVNIAGI GEPGEVTDVI EMKDRLVSPD LQLDASVRDR 17460
IVVHAGGVIR IIAYVSGKPP PTVTWNMNER TLPQEATIET TAISSSMVIK NCQRSHQGVY 17520
SLLAKNEAGE RKKTIIVDVL DVPGPVGTPF LAHNLTNESC KLTWFSPEDD GGSPITNYVI 17580
EKRESDRRAW TPVTYTVTRQ NATVQGLIQG KAYFFRIAAE NSIGMGPFVE TSEALVIREP 17640
ITVPERPEDL EVKEVTKNTV TLTWNPPKYD GGSEIINYVL ESRLIGTEKF HKVTNDNLLS 17700
RKYTVKGLKE GDTYEYRVSA VNIVGQGKPS FCTKPITCKD ELAPPTLHLD FRDKLTIRVG 17760
EAFALTGRYS GKPKPKVSWF KDEADVLEDD RTHIKTTPAT LALEKIKAKR SDSGKYCVVV 17820
ENSTGSRKGF CQVNVVDRPG PPVGPVSFDE VTKDYMVISW KPPLDDGGSK ITNYIIEKKE 17880
VGKDVWMPVT SASAKTTCKV SKLLEGKDYI FRIHAENLYG ISDPLVSDSM KAKDRFRVPD 17940
APDQPIVTEV TKDSALVTWN KPHDGGKPIT NYILEKRETM SKRWARVTKD PIHPYTKFRV 18000
PDLLEGCQYE FRVSAENEIG IGDPSPPSKP VFAKDPIAKP SPPVNPEAID TTCNSVDLTW 18060
QPPRHDGGSK ILGYIVEYQK VGDEEWRRAN HTPESCPETK YKVTGLRDGQ TYKFRVLAVN 18120
AAGESDPAHV PEPVLVKDRL EPPELILDAN MAREQHIKVG DTLRLSAIIK GVPFPKVTWK 18180
KEDRDAPTKA RIDVTPVGSK LEIRNAAHED GGIYSLTVEN PAGSKTVSVK VLVLDKPGPP 18240
RDLEVSEIRK DSCYLTWKEP LDDGGSVITN YVVERRDVAS AQWSPLSATS KKKSHFAKHL 18300
NEGNQYLFRV AAENQYGRGP FVETPKPIKA LDPLHPPGPP KDLHHVDVDK TEVSLVWNKP 18360
DRDGGSPITG YLVEYQEEGT QDWIKFKTVT NLECVVTGLQ QGKTYRFRVK AENIVGLGLP 18420
DTTIPIECQE KLVPPSVELD VKLIEGLVVK AGTTVRFPAI IRGVPVPTAK WTTDGSEIKT 18480
DEHYTVETDN FSSVLTIKNC LRRDTGEYQI TVSNAAGSKT VAVHLTVLDV PGPPTGPINI 18540
LDVTPEHMTI SWQPPKDDGG SPVINYIVEK QDTRKDTWGV VSSGSSKTKL KIPHLQKGCE 18600
YVFRVRAENK IGVGPPLDST PTVAKHKFSP PSPPGKPVVT DITENAATVS WTLPKSDGGS 18660
PITGYYMERR EVTGKWVRVN KTPIADLKFR VTGLYEGNTY EFRVFAENLA GLSKPSPSSD 18720
PIKACRPIKP PGPPINPKLK DKSRETADLV WTKPLSDGGS PILGYVVECQ KPGTAQWNRI 18780
NKDELIRQCA FRVPGLIEGN EYRFRIKAAN IVGEGEPREL AESVIAKDIL HPPEVELDVT 18840
CRDVITVRVG QTIRILARVK GRPEPDITWT KEGKVLVREK RVDLIQDLPR VELQIKEAVR 18900
ADHGKYIISA KNSSGHAQGS AIVNVLDRPG PCQNLKVTNV TKENCTISWE NPLDNGGSEI 18960
TNFIVEYRKP NQKGWSIVAS DVTKRLIKAN LLANNEYYFR VCAENKVGVG PTIETKTPIL 19020
AINPIDRPGE PENLHIADKG KTFVYLKWRR PDYDGGSPNL SYHVERRLKG SDDWERVHKG 19080
SIKETHYMVD RCVENQIYEF RVQTKNEGGE SDWVKTEEVV VKEDLQKPVL DLKLSGVLTV 19140
KAGDTIRLEA GVRGKPFPEV AWTKDKDATD LTRSPRVKID TRADSSKFSL TKAKRSDGGK 19200
YVVTATNTAG SFVAYATVNV LDKPGPVRNL KIVDVSSDRC TVCWDPPEDD GGCEIQNYIL 19260
EKCETKRMVW STYSATVLTP GTTVTRLIEG NEYIFRVRAE NKIGTGPPTE SKPVIAKTKY 19320
DKPGRPDPPE VTKVSKEEMT VVWNPPEYDG GKSITGYFLE KKEKHSTRWV PVNKSAIPER 19380
RMKVQNLLPD HEYQFRVKAE NEIGIGEPSL PSRPVVAKDP IEPPGPPTNF RVVDTTKHSI 19440
TLGWGKPVYD GGAPIIGYVV EMRPKIADAS PDEGWKRCNA AAQLVRKEFT VTSLDENQEY 19500
EFRVCAQNQV GIGRPAELKE AIKPKEILEP PEIDLDASMR KLVIVRAGCP IRLFAIVRGR 19560
PAPKVTWRKV GIDNVVRKGQ VDLVDTMAFL VIPNSTRDDS GKYSLTLVNP AGEKAVFVNV 19620
RVLDTPGPVS DLKVSDVTKT SCHVSWAPPE NDGGSQVTHY IVEKREADRK TWSTVTPEVK 19680
KTSFHVTNLV PGNEYYFRVT AVNEYGPGVP TDVPKPVLAS DPLSEPDPPR KLEVTEMTKN 19740
SATLAWLPPL RDGGAKIDGY ITSYREEEQP ADRWTEYSVV KDLSLVVTGL KEGKKYKFRV 19800
AARNAVGVSL PREAEGVYEA KEQLLPPKIL MPEQITIKAG KKLRIEAHVY GKPHPTCKWK 19860
KGEDEVVTSS HLAVHKADSS SILIIKDVTR KDSGYYSLTA ENSSGTDTQK IKVVVMDAPG 19920
PPQPPFDISD IDADACSLSW HIPLEDGGSN ITNYIVEKCD VSRGDWVTAL ASVTKTSCRV 19980
GKLIPGQEYI FRVRAENRFG ISEPLTSPKM VAQFPFGVPS EPKNARVTKV NKDCIFVAWD 20040
RPDSDGGSPI IGYLIERKER NSLLWVKAND TLVRSTEYPC AGLVEGLEYS FRIYALNKAG 20100
SSPPSKPTEY VTARMPVDPP GKPEVIDVTK STVSLIWARP KHDGGSKIIG YFVEACKLPG 20160
DKWVRCNTAP HQIPQEEYTA TGLEEKAQYQ FRAIARTAVN ISPPSEPSDP VTILAENVPP 20220
RIDLSVAMKS LLTVKAGTNV CLDATVFGKP MPTVSWKKDG TLLKPAEGIK MAMQRNLCTL 20280
ELFSVNRKDS GDYTITAENS SGSKSATIKL KVLDKPGPPA SVKINKMYSD RAMLSWEPPL 20340
EDGGSEITNY IVDKRETSRP NWAQVSATVP ITSCSVEKLI EGHEYQFRIC AENKYGVGDP 20400
VFTEPAIAKN PYDPPGRCDP PVISNITKDH MTVSWKPPAD DGGSPITGYL LEKRETQAVN 20460
WTKVNRKPII ERTLKATGLQ EGTEYEFRVT AINKAGPGKP SDASKAAYAR DPQYPPGPPA 20520
FPKVYDTTRS SVSLSWGKPA YDGGSPIIGY LVEVKRADSD NWVRCNLPQN LQKTRFEVTG 20580
LMEDTQYQFR VYAVNKIGYS DPSDVPDKHY PKDILIPPEG ELDADLRKTL ILRAGVTMRL 20640
YVPVKGRPPP KITWSKPNVN LRDRIGLDIK STDFDTFLRC ENVNKYDAGK YILTLENSCG 20700
KKEYTIVVKV LDTPGPPVNV TVKEISKDSA YVTWEPPIID GGSPIINYVV QKRDAERKSW 20760
STVTTECSKT SFRVANLEEG KSYFFRVFAE NEYGIGDPGE TRDAVKASQT PGPVVDLKVR 20820
SVSKSSCSIG WKKPHSDGGS RIIGYVVDFL TEENKWQRVM KSLSLQYSAK DLTEGKEYTF 20880
RVSAENENGE GTPSEITVVA RDDVVAPDLD LKGLPDLCYL AKENSNFRLK IPIKGKPAPS 20940
VSWKKGEDPL ATDTRVSVES SAVNTTLIVY DCQKSDAGKY TITLKNVAGT KEGTISIKVV 21000
GKPGIPTGPI KFDEVTAEAM TLKWAPPKDD GGSEITNYIL EKRDSVNNKW VTCASAVQKT 21060
TFRVTRLHEG MEYTFRVSAE NKYGVGEGLK SEPIVARHPF DVPDAPPPPN IVDVRHDSVS 21120
LTWTDPKKTG GSPITGYHLE FKERNSLLWK RANKTPIRMR DFKVTGLTEG LEYEFRVMAI 21180
NLAGVGKPSL PSEPVVALDP IDPPGKPEVI NITRNSVTLI WTEPKYDGGH KLTGYIVEKR 21240
DLPSKSWMKA NHVNVPECAF TVTDLVEGGK YEFRIRAKNT AGAISAPSES TETIICKDEY 21300
EAPTIVLDPT IKDGLTIKAG DTIVLNAISI LGKPLPKSSW SKAGKDIRPS DITQITSTPT 21360
SSMLTIKYAT RKDAGEYTIT ATNPFGTKVE HVKVTVLDVP GPPGPVEISN VSAEKATLTW 21420
TPPLEDGGSP IKSYILEKRE TSRLLWTVVS EDIQSCRHVA TKLIQGNEYI FRVSAVNHYG 21480
KGEPVQSEPV KMVDRFGPPG PPEKPEVSNV TKNTATVSWK RPVDDGGSEI TGYHVERREK 21540
KSLRWVRAIK TPVSDLRCKV TGLQEGSTYE FRVSAENRAG IGPPSEASDS VLMKDAAYPP 21600
GPPSNPHVTD TTKKSASLAW GKPHYDGGLE ITGYVVEHQK VGDEAWIKDT TGTALRITQF 21660
VVPDLQTKEK YNFRISAIND AGVGEPAVIP DVEIVEREMA PDFELDAELR RTLVVRAGLS 21720
IRIFVPIKGR PAPEVTWTKD NINLKNRANI ENTESFTLLI IPECNRYDTG KFVMTIENPA 21780
GKKSGFVNVR VLDTPGPVLN LRPTDITKDS VTLHWDLPLI DGGSRITNYI VEKREATRKS 21840
YSTATTKCHK CTYKVTGLSE GCEYFFRVMA ENEYGIGEPT ETTEPVKASE APSPPDSLNI 21900
MDITKSTVSL AWPKPKHDGG SKITGYVIEA QRKGSDQWTH ITTVKGLECV VRNLTEGEEY 21960
TFQVMAVNSA GRSAPRESRP VIVKEQTMLP ELDLRGIYQK LVIAKAGDNI KVEIPVLGRP 22020
KPTVTWKKGD QILKQTQRVN FETTATSTIL NINECVRSDS GPYPLTARNI VGEVGDVITI 22080
QVHDIPGPPT GPIKFDEVSS DFVTFSWDPP ENDGGVPISN YVVEMRQTDS TTWVELATTV 22140
IRTTYKATRL TTGLEYQFRV KAQNRYGVGP GITSACIVAN YPFKVPGPPG TPQVTAVTKD 22200
SMTISWHEPL SDGGSPILGY HVERKERNGI LWQTVSKALV PGNIFKSSGL TDGIAYEFRV 22260
IAENMAGKSK PSKPSEPMLA LDPIDPPGKP VPLNITRHTV TLKWAKPEYT GGFKITSYIV 22320
EKRDLPNGRW LKANFSNILE NEFTVSGLTE DAAYEFRVIA KNAAGAISPP SEPSDAITCR 22380
DDVEAPKIKV DVKFKDTVIL KAGEAFRLEA DVSGRPPPTM EWSKDGKELE GTAKLEIKIA 22440
DFSTNLVNKD STRRDSGAYT LTATNPGGFA KHIFNVKVLD RPGPPEGPLA VTEVTSEKCV 22500
LSWFPPLDDG GAKIDHYIVQ KRETSRLAWT NVASEVQVTK LKVTKLLKGN EYIFRVMAVN 22560
KYGVGEPLES EPVLAVNPYG PPDPPKNPEV TTITKDSMVV CWGHPDSDGG SEIINYIVER 22620
RDKAGQRWIK CNKKTLTDLR YKVSGLTEGH EYEFRIMAEN AAGISAPSPT SPFYKACDTV 22680
FKPGPPGNPR VLDTSRSSIS IAWNKPIYDG GSEITGYMVE IALPEEDEWQ IVTPPAGLKA 22740
TSYTITGLTE NQEYKIRIYA MNSEGLGEPA LVPGTPKAED RMLPPEIELD ADLRKVVTIR 22800
ACCTLRLFVP IKGRPAPEVK WARDHGESLD KASIESTSSY TLLIVGNVNR FDSGKYILTV 22860
ENSSGSKSAF VNVRVLDTPG PPQDLKVKEV TKTSVTLTWD PPLLDGGSKI KNYIVEKRES 22920
TRKAYSTVAT NCHKTSWKVD QLQEGCSYYF RVLAENEYGI GLPAETAESV KASERPLPPG 22980
KITLMDVTRN SVSLSWEKPE HDGGSRILGY IVEMQTKGSD KWATCATVKV TEATITGLIQ 23040
GEEYSFRVSA QNEKGISDPR QLSVPVIAKD LVIPPAFKLL FNTFTVLAGE DLKVDVPFIG 23100
RPTPAVTWHK DNVPLKQTTR VNAESTENNS LLTIKDACRE DVGHYVVKLT NSAGEAIETL 23160
NVIVLDKPGP PTGPVKMDEV TADSITLSWG PPKYDGGSSI NNYIVEKRDT STTTWQIVSA 23220
TVARTTIKAC RLKTGCEYQF RIAAENRYGK STYLNSEPTV AQYPFKVPGP PGTPVVTLSS 23280
RDSMEVQWNE PISDGGSRVI GYHLERKERN SILWVKLNKT PIPQTKFKTT GLEEGVEYEF 23340
RVSAENIVGI GKPSKVSECY VARDPCDPPG RPEAIIVTRN SVTLQWKKPT YDGGSKITGY 23400
IVEKKELPEG RWMKASFTNI IDTHFEVTGL VEDHRYEFRV IARNAAGVFS EPSESTGAIT 23460
ARDEVDPPRI SMDPKYKDTI VVHAGESFKV DADIYGKPIP TIQWIKGDQE LSNTARLEIK 23520
STDFATSLSV KDAVRVDSGN YILKAKNVAG ERSVTVNVKV LDRPGPPEGP VVISGVTAEK 23580
CTLAWKPPLQ DGGSDIINYI VERRETSRLV WTVVDANVQT LSCKVTKLLE GNEYTFRIMA 23640
VNKYGVGEPL ESEPVVAKNP FVVPDAPKAP EVTTVTKDSM IVVWERPASD GGSEILGYVL 23700
EKRDKEGIRW TRCHKRLIGE LRLRVTGLIE NHDYEFRVSA ENAAGLSEPS PPSAYQKACD 23760
PIYKPGPPNN PKVIDITRSS VFLSWSKPIY DGGCEIQGYI VEKCDVSVGE WTMCTPPTGI 23820
NKTNIEVEKL LEKHEYNFRI CAINKAGVGE HADVPGPIIV EEKLEAPDID LDLELRKIIN 23880
IRAGGSLRLF VPIKGRPTPE VKWGKVDGEI RDAAIIDVTS SFTSLVLDNV NRYDSGKYTL 23940
TLENSSGTKS AFVTVRVLDT PSPPVNLKVT EITKDSVSIT WEPPLLDGGS KIKNYIVEKR 24000
EATRKSYAAV VTNCHKNSWK IDQLQEGCSY YFRVTAENEY GIGLPAQTAD PIKVAEVPQP 24060
PGKITVDDVT RNSVSLSWTK PEHDGGSKII QYIVEMQAKH SEKWSECARV KSLQAVITNL 24120
TQGEEYLFRV VAVNEKGRSD PRSLAVPIVA KDLVIEPDVK PAFSSYSVQV GQDLKIEVPI 24180
SGRPKPTITW TKDGLPLKQT TRINVTDSLD LTTLSIKETH KDDGGQYGIT VANVVGQKTA 24240
SIEIVTLDKP DPPKGPVKFD DVSAESITLS WNPPLYTGGC QITNYIVQKR DTTTTVWDVV 24300
SATVARTTLK VTKLKTGTEY QFRIFAENRY GQSFALESDP IVAQYPYKEP GPPGTPFATA 24360
ISKDSMVIQW HEPVNNGGSP VIGYHLERKE RNSILWTKVN KTIIHDTQFK AQNLEEGIEY 24420
EFRVYAENIV GVGKASKNSE CYVARDPCDP PGTPEPIMVK RNEITLQWTK PVYDGGSMIT 24480
GYIVEKRDLP DGRWMKASFT NVIETQFTVS GLTEDQRYEF RVIAKNAAGA ISKPSDSTGP 24540
ITAKDEVELP RISMDPKFRD TIVVNAGETF RLEADVHGKP LPTIEWLRGD KEIEESARCE 24600
IKNTDFKALL IVKDAIRIDG GQYILRASNV AGSKSFPVNV KVLDRPGPPE GPVQVTGVTS 24660
EKCSLTWSPP LQDGGSDISH YVVEKRETSR LAWTVVASEV VTNSLKVTKL LEGNEYVFRI 24720
MAVNKYGVGE PLESAPVLMK NPFVLPGPPK SLEVTNIAKD SMTVCWNRPD SDGGSEIIGY 24780
IVEKRDRSGI RWIKCNKRRI TDLRLRVTGL TEDHEYEFRV SAENAAGVGE PSPATVYYKA 24840
CDPVFKPGPP TNAHIVDTTK NSITLAWGKP IYDGGSEILG YVVEICKADE EEWQIVTPQT 24900
GLRVTRFEIS KLTEHQEYKI RVCALNKVGL GEATSVPGTV KPEDKLEAPE LDLDSELRKG 24960
IVVRAGGSAR IHIPFKGRPT PEITWSREEG EFTDKVQIEK GVNYTQLSID NCDRNDAGKY 25020
ILKLENSSGS KSAFVTVKVL DTPGPPQNLA VKEVRKDSAF LVWEPPIIDG GAKVKNYVID 25080
KRESTRKAYA NVSSKCSKTS FKVENLTEGA IYYFRVMAEN EFGVGVPVET VDAVKAAEPP 25140
SPPGKVTLTD VSQTSASLMW EKPEHDGGSR VLGYVVEMQP KGTEKWSIVA ESKVCNAVVT 25200
GLSSGQEYQF RVKAYNEKGK SDPRVLGVPV IAKDLTIQPS LKLPFNTYSI QAGEDLKIEI 25260
PVIGRPRPNI SWVKDGEPLK QTTRVNVEET ATSTVLHIKE GNKDDFGKYT VTATNSAGTA 25320
TENLSVIVLE KPGPPVGPVR FDEVSADFVV ISWEPPAYTG GCQISNYIVE KRDTTTTTWH 25380
MVSATVARTT IKITKLKTGT EYQFRIFAEN RYGKSAPLDS KAVIVQYPFK EPGPPGTPFV 25440
TSISKDQMLV QWHEPVNDGG TKIIGYHLEQ KEKNSILWVK LNKTPIQDTK FKTTGLDEGL 25500
EYEFKVSAEN IVGIGKPSKV SECFVARDPC DPPGRPEAIV ITRNNVTLKW KKPAYDGGSK 25560
ITGYIVEKKD LPDGRWMKAS FTNVLETEFT VSGLVEDQRY EFRVIARNAA GNFSEPSDSS 25620
GAITARDEID APNASLDPKY KDVIVVHAGE TFVLEADIRG KPIPDVVWSK DGKELEETAA 25680
RMEIKSTIQK TTLVVKDCIR TDGGQYILKL SNVGGTKSIP ITVKVLDRPG PPEGPLKVTG 25740
VTAEKCYLAW NPPLQDGGAN ISHYIIEKRE TSRLSWTQVS TEVQALNYKV TKLLPGNEYI 25800
FRVMAVNKYG IGEPLESGPV TACNPYKPPG PPSTPEVSAI TKDSMVVTWA RPVDDGGTEI 25860
EGYILEKRDK EGVRWTKCNK KTLTDLRLRV TGLTEGHSYE FRVAAENAAG VGEPSEPSVF 25920
YRACDALYPP GPPSNPKVTD TSRSSVSLAW SKPIYDGGAP VKGYVVEVKE AAADEWTTCT 25980
PPTGLQGKQF TVTKLKENTE YNFRICAINS EGVGEPATLP GSVVAQERIE PPEIELDADL 26040
RKVVVLRASA TLRLFVTIKG RPEPEVKWEK AEGILTDRAQ IEVTSSFTML VIDNVTRFDS 26100
GRYNLTLENN SGSKTAFVNV RVLDSPSAPV NLTIREVKKD SVTLSWEPPL IDGGAKITNY 26160
IVEKRETTRK AYATITNNCT KTTFRIENLQ EGCSYYFRVL ASNEYGIGLP AETTEPVKVS 26220
EPPLPPGRVT LVDVTRNTAT IKWEKPESDG GSKITGYVVE MQTKGSEKWS TCTQVKTLEA 26280
TISGLTAGEE YVFRVAAVNE KGRSDPRQLG VPVIARDIEI KPSVELPFHT FNVKAREQLK 26340
IDVPFKGRPQ ATVNWRKDGQ TLKETTRVNV SSSKTVTSLS IKEASKEDVG TYELCVSNSA 26400
GSITVPITII VLDRPGPPGP IRIDEVSCDS ITISWNPPEY DGGCQISNYI VEKKETTSTT 26460
WHIVSQAVAR TSIKIVRLTT GSEYQFRVCA ENRYGKSSYS ESSAVVAEYP FSPPGPPGTP 26520
KVVHATKSTM LVTWQVPVND GGSRVIGYHL EYKERSSILW SKANKILIAD TQMKVSGLDE 26580
GLMYEYRVYA ENIAGIGKCS KSCEPVPARD PCDPPGQPEV TNITRKSVSL KWSKPHYDGG 26640
AKITGYIVER RELPDGRWLK CNYTNIQETY FEVTELTEDQ RYEFRVFARN AADSVSEPSE 26700
STGPIIVKDD VEPPRVMMDV KFRDVIVVKA GEVLKINADI AGRPLPVISW AKDGIEIEER 26760
ARTEIISTDN HTLLTVKDCI RRDTGQYVLT LKNVAGTRSV AVNCKVLDKP GPPAGPLEIN 26820
GLTAEKCSLS WGRPQEDGGA DIDYYIVEKR ETSHLAWTIC EGELQMTSCK VTKLLKGNEY 26880
IFRVTGVNKY GVGEPLESVA IKALDPFTVP SPPTSLEITS VTKESMTLCW SRPESDGGSE 26940
ISGYIIERRE KNSLRWVRVN KKPVYDLRVK STGLREGCEY EYRVYAENAA GLSLPSETSP 27000
LIRAEDPVFL PSPPSKPKIV DSGKTTITIA WVKPLFDGGA PITGYTVEYK KSDDTDWKTS 27060
IQSLRGTEYT ISGLTTGAEY VFRVKSVNKV GASDPSDSSD PQIAKEREEE PLFDIDSEMR 27120
KTLIVKAGAS FTMTVPFRGR PVPNVLWSKP DTDLRTRAYV DTTDSRTSLT IENANRNDSG 27180
KYTLTIQNVL SAASLTLVVK VLDTPGPPTN ITVQDVTKES AVLSWDVPEN DGGAPVKNYH 27240
IEKREASKKA WVSVTNNCNR LSYKVTNLQE GAIYYFRVSG ENEFGVGIPA ETKEGVKITE 27300
KPSPPEKLGV TSISKDSVSL TWLKPEHDGG SRIVHYVVEA LEKGQKNWVK CAVAKSTHHV 27360
VSGLRENSEY FFRVFAENQA GLSDPRELLL PVLIKEQLEP PEIDMKNFPS HTVYVRAGSN 27420
LKVDIPISGK PLPKVTLSRD GVPLKATMRF NTEITAENLT INLKESVTAD AGRYEITAAN 27480
SSGTTKAFIN IVVLDRPGPP TGPVVISDIT EESVTLKWEP PKYDGGSQVT NYILLKRETS 27540
TAVWTEVSAT VARTMMKVMK LTTGEEYQFR IKAENRFGIS DHIDSACVTV KLPYTTPGPP 27600
STPWVTNVTR ESITVGWHEP VSNGGSAVVG YHLEMKDRNS ILWQKANKLV IRTTHFKVTT 27660
ISAGLIYEFR VYAENAAGVG KPSHPSEPVL AIDACEPPRN VRITDISKNS VSLSWQQPAF 27720
DGGSKITGYI VERRDLPDGR WTKASFTNVT ETQFIISGLT QNSQYEFRVF ARNAVGSISN 27780
PSEVVGPITC IDSYGGPVID LPLEYTEVVK YRAGTSVKLR AGISGKPAPT IEWYKDDKEL 27840
QTNALVCVEN TTDLASILIK DADRLNSGCY ELKLRNAMGS ASATIRVQIL DKPGPPGGPI 27900
EFKTVTAEKI TLLWRPPADD GGAKITHYIV EKRETSRVVW SMVSEHLEEC IITTTKIIKG 27960
NEYIFRVRAV NKYGIGEPLE SDSVVAKNAF VTPGPPGIPE VTKITKNSMT VVWSRPIADG 28020
GSDISGYFLE KRDKKSLGWF KVLKETIRDT RQKVTGLTEN SDYQYRVCAV NAAGQGPFSE 28080
PSEFYKAADP IDPPGPPAKI RIADSTKSSI TLGWSKPVYD GGSAVTGYVV EIRQGEEEEW 28140
TTVSTKGEVR TTEYVVSNLK PGVNYYFRVS AVNCAGQGEP IEMNEPVQAK DILEAPEIDL 28200
DVALRTSVIA KAGEDVQVLI PFKGRPPPTV TWRKDEKNLG SDARYSIENT DSSSLLTIPQ 28260
VTRNDTGKYI LTIENGVGEP KSSTVSVKVL DTPAACQKLQ VKHVSRGTVT LLWDPPLIDG 28320
GSPIINYVIE KRDATKRTWS VVSHKCSSTS FKLIDLSEKT PFFFRVLAEN EIGIGEPCET 28380
TEPVKAAEVP APIRDLSMKD STKTSVILSW TKPDFDGGSV ITEYVVERKG KGEQTWSHAG 28440
ISKTCEIEVS QLKEQSVLEF RVFAKNEKGL SDPVTIGPIT VKELIITPEV DLSDIPGAQV 28500
TVRIGHNVHL ELPYKGKPKP SISWLKDGLP LKESEFVRFS KTENKITLSI KNAKKEHGGK 28560
YTVILDNAVC RIAVPITVIT LGPPSKPKGP IRFDEIKADS VILSWDVPED NGGGEITCYS 28620
IEKRETSQTN WKMVCSSVAR TTFKVPNLVK DAEYQFRVRA ENRYGVSQPL VSSIIVAKHQ 28680
FRIPGPPGKP VIYNVTSDGM SLTWDAPVYD GGSEVTGFHV EKKERNSILW QKVNTSPISG 28740
REYRATGLVE GLDYQFRVYA ENSAGLSSPS DPSKFTLAVS PVDPPGTPDY IDVTRETITL 28800
KWNPPLRDGG SKIVGYSIEK RQGNERWVRC NFTDVSECQY TVTGLSPGDR YEFRIIARNA 28860
VGTISPPSQS SGIIMTRDEN VPPIVEFGPE YFDGLIIKSG ESLRIKALVQ GRPVPRVTWF 28920
KDGVEIEKRM NMEITDVLGS TSLFVRDATR DHRGVYTVEA KNASGSAKAE IKVKVQDTPG 28980
KVVGPIRFTN ITGEKMTLWW DAPLNDGCAP ITHYIIEKRE TSRLAWALIE DKCEAQSYTA 29040
IKLINGNEYQ FRVSAVNKFG VGRPLDSDPV VAQIQYTVPD APGIPEPSNI TGNSITLTWA 29100
RPESDGGSEI QQYILERREK KSTRWVKVIS KRPISETRFK VTGLTEGNEY EFHVMAENAA 29160
GVGPASGISR LIKCREPVNP PGPPTVVKVT DTSKTTVSLE WSKPVFDGGM EIIGYIIEMC 29220
KADLGDWHKV NAEACVKTRY TVTDLQAGEE YKFRVSAING AGKGDSCEVT GTIKAVDRLT 29280
APELDIDANF KQTHVVRAGA SIRLFIAYQG RPTPTAVWSK PDSNLSLRAD IHTTDSFSTL 29340
TVENCNRNDA GKYTLTVENN SGSKSITFTV KVLDTPGPPG PITFKDVTRG SATLMWDAPL 29400
LDGGARIHHY VVEKREASRR SWQVISEKCT RQIFKVNDLA EGVPYYFRVS AVNEYGVGEP 29460
YEMPEPIVAT EQPAPPRRLD VVDTSKSSAV LAWLKPDHDG GSRITGYLLE MRQKGSDFWV 29520
EAGHTKQLTF TVERLVEKTE YEFRVKAKND AGYSEPREAF SSVIIKEPQI EPTADLTGIT 29580
NQLITCKAGS PFTIDVPISG RPAPKVTWKL EEMRLKETDR VSITTTKDRT TLTVKDSMRG 29640
DSGRYFLTLE NTAGVKTFSV TVVVIGRPGP VTGPIEVSSV SAESCVLSWG EPKDGGGTEI 29700
TNYIVEKRES GTTAWQLVNS SVKRTQIKVT HLTKYMEYSF RVSSENRFGV SKPLESAPII 29760
AEHPFVPPSA PTRPEVYHVS ANAMSIRWEE PYHDGGSKII GYWVEKKERN TILWVKENKV 29820
PCLECNYKVT GLVEGLEYQF RTYALNAAGV SKASEASRPI MAQNPVDAPG RPEVTDVTRS 29880
TVSLIWSAPA YDGGSKVVGY IIERKPVSEV GDGRWLKCNY TIVSDNFFTV TALSEGDTYE 29940
FRVLAKNAAG VISKGSESTG PVTCRDEYAP PKAELDARLH GDLVTIRAGS DLVLDAAVGG 30000
KPEPKIIWTK GDKELDLCEK VSLQYTGKRA TAVIKFCDRS DSGKYTLTVK NASGTKAVSV 30060
MVKVLDSPGP CGKLTVSRVT QEKCTLAWSL PQEDGGAEIT HYIVERRETS RLNWVIVEGE 30120
CPTLSYVVTR LIKNNEYIFR VRAVNKYGPG VPVESEPIVA RNSFTIPSPP GIPEEVGTGK 30180
EHIIIQWTKP ESDGGNEISN YLVDKREKKS LRWTRVNKDY VVYDTRLKVT SLMEGCDYQF 30240
RVTAVNAAGN SEPSEASNFI SCREPSYTPG PPSAPRVVDT TKHSISLAWT KPMYDGGTDI 30300
VGYVLEMQEK DTDQWYRVHT NATIRNTEFT VPDLKMGQKY SFRVAAVNVK GMSEYSESIA 30360
EIEPVERIEI PDLELADDLK KTVTIRAGAS LRLMVSVSGR PPPVITWSKQ GIDLASRAII 30420
DTTESYSLLI VDKVNRYDAG KYTIEAENQS GKKSATVLVK VYDTPGPCPS VKVKEVSRDS 30480
VTITWEIPTI DGGAPVNNYI VEKREAAMRA FKTVTTKCSK TLYRISGLVE GTMYYFRVLP 30540
ENIYGIGEPC ETSDAVLVSE VPLVPAKLEV VDVTKSTVTL AWEKPLYDGG SRLTGYVLEA 30600
CKAGTERWMK VVTLKPTVLE HTVTSLNEGE QYLFRIRAQN EKGVSEPRET VTAVTVQDLR 30660
VLPTIDLSTM PQKTIHVPAG RPVELVIPIA GRPPPAASWF FAGSKLRESE RVTVETHTKV 30720
AKLTIRETTI RDTGEYTLEL KNVTGTTSET IKVIILDKPG PPTGPIKIDE IDATSITISW 30780
EPPELDGGAP LSGYVVEQRD AHRPGWLPVS ESVTRSTFKF TRLTEGNEYV FRVAATNRFG 30840
IGSYLQSEVI ECRSSIRIPG PPETLQIFDV SRDGMTLTWY PPEDDGGSQV TGYIVERKEV 30900
RADRWVRVNK VPVTMTRYRS TGLTEGLEYE HRVTAINARG SGKPSRPSKP IVAMDPIAPP 30960
GKPQNPRVTD TTRTSVSLAW SVPEDEGGSK VTGYLIEMQK VDQHEWTKCN TTPTKIREYT 31020
LTHLPQGAEY RFRVLACNAG GPGEPAEVPG TVKVTEMLEY PDYELDERYQ EGIFVRQGGV 31080
IRLTIPIKGK PFPICKWTKE GQDISKRAMI ATSETHTELV IKEADRGDSG TYDLVLENKC 31140
GKKAVYIKVR VIGSPNSPEG PLEYDDIQVR SVRVSWRPPA DDGGADILGY ILERREVPKA 31200
AWYTIDSRVR GTSLVVKGLK ENVEYHFRVS AENQFGISKP LKSEEPVTPK TPLNPPEPPS 31260
NPPEVLDVTK SSVSLSWSRP KDDGGSRVTG YYIERKETST DKWVRHNKTQ ITTTMYTVTG 31320
LVPDAEYQFR IIAQNDVGLS ETSPASEPVV CKDPFDKPSQ PGELEILSIS KDSVTLQWEK 31380
PECDGGKEIL GYWVEYRQSG DSAWKKSNKE RIKDKQFTIG GLLEATEYEF RVFAENETGL 31440
SRPRRTAMSI KTKLTSGEAP GIRKEMKDVT TKLGEAAQLS CQIVGRPLPD IKWYRFGKEL 31500
IQSRKYKMSS DGRTHTLTVM TEEQEDEGVY TCIATNEVGE VETSSKLLLQ ATPQFHPGYP 31560
LKEKYYGAVG STLRLHVMYI GRPVPAMTWF HGQKLLQNSE NITIENTEHY THLVMKNVQR 31620
KTHAGKYKVQ LSNVFGTVDA ILDVEIQDKP DKPTGPIVIE ALLKNSAVIS WKPPADDGGS 31680
WITNYVVEKC EAKEGAEWQL VSSAISVTTC RIVNLTENAG YYFRVSAQNT FGISDPLEVS 31740
SVVIIKSPFE KPGAPGKPTI TAVTKDSCVV AWKPPASDGG AKIRNYYLEK REKKQNKWIS 31800
VTTEEIRETV FSVKNLIEGL EYEFRVKCEN LGGESEWSEI SEPITPKSDV PIQAPHFKEE 31860
LRNLNVRYQS NATLVCKVTG HPKPIVKWYR QGKEIIADGL KYRIQEFKGG YHQLIIASVT 31920
DDDATVYQVR ATNQGGSVSG TASLEVEVPA KIHLPKTLEG MGAVHALRGE VVSIKIPFSG 31980
KPDPVITWQK GQDLIDNNGH YQVIVTRSFT SLVFPNGVER KDAGFYVVCA KNRFGIDQKT 32040
VELDVADVPD PPRGVKVSDV SRDSVNLTWT EPASDGGSKI TNYIVEKCAT TAERWLRVGQ 32100
ARETRYTVIN LFGKTSYQFR VIAENKFGLS KPSEPSEPTI TKEDKTRAMN YDEEVDETRE 32160
VSMTKASHSS TKELYEKYMI AEDLGRGEFG IVHRCVETSS KKTYMAKFVK VKGTDQVLVK 32220
KEISILNIAR HRNILHLHES FESMEELVMI FEFISGLDIF ERINTSAFEL NEREIVSYVH 32280
QVCEALQFLH SHNIGHFDIR PENIIYQTRR SSTIKIIEFG QARQLKPGDN FRLLFTAPEY 32340
YAPEVHQHDV VSTATDMWSL GTLVYVLLSG INPFLAETNQ QIIENIMNAE YTFDEEAFKE 32400
ISIEAMDFVD RLLVKERKSR MTASEALQHP WLKQKIERVS TKVIRTLKHR RYYHTLIKKD 32460
LNMVVSAARI SCGGAIRSQK GVSVAKVKVA SIEIGPVSGQ IMHAVGEEGG HVKYVCKIEN 32520
YDQSTQVTWY FGVRQLENSE KYEITYEDGV AILYVKDITK LDDGTYRCKV VNDYGEDSSY 32580
AELFVKGVRE VYDYYCRRTM KKIKRRTDTM RLLERPPEFT LPLYNKTAYV GENVRFGVTI 32640
TVHPEPHVTW YKSGQKIKPG DNDKKYTFES DKGLYQLTIN SVTTDDDAEY TVVARNKYGE 32700
DSCKAKLTVT LHPPPTDSTL RPMFKRLLAN AECQEGQSVC FEIRVSGIPP PTLKWEKDGQ 32760
PLSLGPNIEI IHEGLDYYAL HIRDTLPEDT GYYRVTATNT AGSTSCQAHL QVERLRYKKQ 32820
EFKSKEEHER HVQKQIDKTL RMAEILSGTE SVPLTQVAKE ALREAAVLYK PAVSTKTVKG 32880
EFRLEIEEKK EERKLRMPYD VPEPRKYKQT TIEEDQRIKQ FVPMSDMKWY KKIRDQYEMP 32940
GKLDRVVQKR PKRIRLSRWE QFYVMPLPRI TDQYRPKWRI PKLSQDDLEI VRPARRRTPS 33000
PDYDFYYRPR RRSLGDISDE ELLLPIDDYL AMKRTEEERL RLEEELELGF SASPPSRSPP 33060
HFELSSLRYS SPQAHVKVEE TRKDFRYSTY HIPTKAEAST SYAELRERHA QAAYRQPKQR 33120
QRIMAEREDE ELLRPVTTTQ HLSEYKSELD FMSKEEKSRK KSRRQREVTE ITEIEEEYEI 33180
SKHAQRESSS SASRLLRRRR SLSPTYIELM RPVSELIRSR PQPAEEYEDD TERRSPTPER 33240
TRPRSPSPVS SERSLSRFER SARFDIFSRY ESMKAALKTQ KTSERKYEVL SQQPFTLDHA 33300
PRITLRMRSH RVPCGQNTRF ILNVQSKPTA EVKWYHNGVE LQESSKIHYT NTSGVLTLEI 33360
LDCHTDDSGT YRAVCTNYKG EASDYATLDV TGGDYTTYAS QRRDEEVPRS VFPELTRTEA 33420
YAVSSFKKTS EMEASSSVRE VKSQMTETRE SLSSYEHSAS AEMKSAALEE KSLEEKSTTR 33480
KIKTTLAARI LTKPRSMTVY EGESARFSCD TDGEPVPTVT WLRKGQVLST SARHQVTTTK 33540
YKSTFEISSV QASDEGNYSV VVENSEGKQE AEFTLTIQKA RVTEKAVTSP PRVKSPEPRV 33600
KSPEAVKSPK RVKSPEPSHP KAVSPTETKP TPTEKVQHLP VSAPPKITQF LKAEASKEIA 33660
KLTCVVESSV LRAKEVTWYK DGKKLKENGH FQFHYSADGT YELKINNLTE SDQGEYVCEI 33720
SGEGGTSKTN LQFMGQAFKS IHEKVSKISE TKKSDQKTTE STVTRKTEPK APEPISSKPV 33780
IVTGLQDTTV SSDSVAKFAV KATGEPRPTA IWTKDGKAIT QGGKYKLSED KGGFFLEIHK 33840
TDTSDSGLYT CTVKNSAGSV SSSCKLTIKA IKDTEAQKVS TQKTSEITPQ KKAVVQEEIS 33900
QKALRSEEIK MSEAKSQEKL ALKEEASKVL ISEEVKKSAA TSLEKSIVHE EITKTSQASE 33960
EVRTHAEIKA FSTQMSINEG QRLVLKANIA GATDVKWVLN GVELTNSEEY RYGVSGSDQT 34020
LTIKQASHRD EGILTCISKT KEGIVKCQYD LTLSKELSDA PAFISQPRSQ NINEGQNVLF 34080
TCEISGEPSP EIEWFKNNLP ISISSNVSIS RSRNVYSLEI RNASVSDSGK YTIKAKNFRG 34140
QCSATASLMV LPLVEEPSRE VVLRTSGDTS LQGSFSSQSV QMSASKQEAS FSSFSSSSAS 34200
SMTEMKFASM SAQSMSSMQE SFVEMSSSSF MGISNMTQLE SSTSKMLKAG IRGIPPKIEA 34260
LPSDISIDEG KVLTVACAFT GEPTPEVTWS CGGRKIHSQE QGRFHIENTD DLTTLIIMDV 34320
QKQDGGLYTL SLGNEFGSDS ATVNIHIRSI 34350 
Gene Ontology
 GO:0000794; C:condensed nuclear chromosome; IDA:BHF-UCL.
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005576; C:extracellular region; TAS:Reactome.
 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0031430; C:M band; IDA:BHF-UCL.
 GO:0005865; C:striated muscle thin filament; IDA:BHF-UCL.
 GO:0030018; C:Z disc; IDA:BHF-UCL.
 GO:0051015; F:actin filament binding; IDA:BHF-UCL.
 GO:0042805; F:actinin binding; IDA:BHF-UCL.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
 GO:0005516; F:calmodulin binding; TAS:UniProtKB.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0043621; F:protein self-association; IDA:BHF-UCL.
 GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
 GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
 GO:0008307; F:structural constituent of muscle; TAS:UniProtKB.
 GO:0031433; F:telethonin binding; ISS:BHF-UCL.
 GO:0007512; P:adult heart development; IEA:Compara.
 GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
 GO:0048739; P:cardiac muscle fiber development; IMP:BHF-UCL.
 GO:0003300; P:cardiac muscle hypertrophy; IMP:BHF-UCL.
 GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
 GO:0055003; P:cardiac myofibril assembly; IMP:BHF-UCL.
 GO:0035995; P:detection of muscle stretch; TAS:BHF-UCL.
 GO:0043056; P:forward locomotion; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0007076; P:mitotic chromosome condensation; IEP:BHF-UCL.
 GO:0030049; P:muscle filament sliding; TAS:Reactome.
 GO:0030168; P:platelet activation; TAS:Reactome.
 GO:0002576; P:platelet degranulation; TAS:Reactome.
 GO:0045859; P:regulation of protein kinase activity; IMP:BHF-UCL.
 GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
 GO:0045214; P:sarcomere organization; IMP:BHF-UCL.
 GO:0048769; P:sarcomerogenesis; IMP:BHF-UCL.
 GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:BHF-UCL.
 GO:0030240; P:skeletal muscle thin filament assembly; IMP:BHF-UCL. 
Interpro
 IPR022682; Calpain_domain_III.
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003599; Ig_sub.
 IPR003598; Ig_sub2.
 IPR011009; Kinase-like_dom.
 IPR004168; PPAK_motif.
 IPR000719; Prot_kinase_cat_dom.
 IPR012337; RNaseH-like_dom.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR015129; Titin_Z.
 IPR008266; Tyr_kinase_AS. 
Pfam
 PF00041; fn3
 PF07679; I-set
 PF00069; Pkinase
 PF02818; PPAK
 PF09042; Titin_Z 
SMART
 SM00060; FN3
 SM00409; IG
 SM00408; IGc2
 SM00220; S_TKc 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST
 PS00625; RCC1_1
 PS00626; RCC1_2
 PS50012; RCC1_3
 PS50005; TPR
 PS50293; TPR_REGION
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS