| Tag | Content |
|---|
| CPLM ID | CPLM-007096 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dynamin-1 |
Protein Synonyms/Alias | |
Gene Name | Dnm1 |
Gene Synonyms/Alias | Dnm; Kiaa4093 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 206 | RTIGVITKLDLMDEG | ubiquitination | [1] | | 223 | ARDVLENKLLPLRRG | ubiquitination | [1] | | 257 | AALAAERKFFLSHPS | ubiquitination | [1] | | 299 | TLPGLRNKLQSQLLS | ubiquitination | [1] | | 309 | SQLLSIEKEVDEYKN | ubiquitination | [1] | | 315 | EKEVDEYKNFRPDDP | ubiquitination | [1] | | 376 | RFPFELVKMEFDEKE | ubiquitination | [1] | | 382 | VKMEFDEKELRREIS | ubiquitination | [1] | | 393 | REISYAIKNIHGIRT | ubiquitination | [1] | | 535 | INNIGIMKGGSKEYW | ubiquitination | [1] | | 571 | MLSVDNLKLRDVEKG | ubiquitination | [1] | | 635 | ERVGDKEKASETEEN | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis (By similarity). |
Sequence Annotation | DOMAIN 515 625 PH.
DOMAIN 659 750 GED.
NP_BIND 38 45 GTP (By similarity).
NP_BIND 136 140 GTP (By similarity).
NP_BIND 205 208 GTP (By similarity).
MOD_RES 80 80 Phosphotyrosine.
MOD_RES 125 125 Nitrated tyrosine; alternate.
MOD_RES 125 125 Phosphotyrosine; alternate.
MOD_RES 347 347 Phosphoserine (By similarity).
MOD_RES 354 354 Phosphotyrosine.
MOD_RES 512 512 Phosphoserine (By similarity).
MOD_RES 778 778 Phosphoserine.
MOD_RES 822 822 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Endocytosis; GTP-binding; Hydrolase; Microtubule; Motor protein; Nitration; Nucleotide-binding; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 867 AA |
Protein Sequence | MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG 60
SGIVTRRPLV LQLVNSTTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI 120
NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD 180
LANSDALKIA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK 240
DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL 300
QSQLLSIEKE VDEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA 360
RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDMAFE TIVKKQVKKI 420
REPCLKCVDM VISELISTVR QCTKKLQQYP RLREEMERIV TTHIREREGR TKEQVMLLID 480
IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE 540
YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY 600
RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE 660
TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE 720
QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SWLQVQSVPA GRRSPTSSPT 780
PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP 840
PGVPSRSGQA SPSRPESPRP PFDL 864 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |