| Tag | Content |
|---|
| CPLM ID | CPLM-006807 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Enolase |
Protein Synonyms/Alias | 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase |
Gene Name | eno |
Gene Synonyms/Alias | BSU33900 |
Created Date | July 27, 2013 |
Organism | Bacillus subtilis (strain 168) |
NCBI Taxa ID | 224308 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 255 | FYNKEDGKYHLSGEG | acetylation | [1] |
|
Reference | [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis. Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG. Proteomics. 2013 May;13(10-11):1726-36. [ PMID: 23468065] |
Functional Description | Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). |
Sequence Annotation | REGION 366 369 Substrate binding (By similarity).
ACT_SITE 205 205 Proton donor (By similarity).
ACT_SITE 339 339 Proton acceptor (By similarity).
METAL 242 242 Magnesium (By similarity).
METAL 287 287 Magnesium (By similarity).
METAL 314 314 Magnesium (By similarity).
BINDING 155 155 Substrate (By similarity).
BINDING 164 164 Substrate (By similarity).
BINDING 287 287 Substrate (By similarity).
BINDING 314 314 Substrate (By similarity).
BINDING 339 339 Substrate (covalent); in inhibited form.
BINDING 390 390 Substrate (By similarity).
MOD_RES 141 141 Phosphothreonine.
MOD_RES 259 259 Phosphoserine.
MOD_RES 281 281 Phosphotyrosine.
MOD_RES 325 325 Phosphoserine. |
Keyword | 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Glycolysis; Lyase; Magnesium; Metal-binding; Phosphoprotein; Reference proteome; Secreted; Sporulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 430 AA |
Protein Sequence | MPYIVDVYAR EVLDSRGNPT VEVEVYTETG AFGRALVPSG ASTGEYEAVE LRDGDKDRYL 60
GKGVLTAVNN VNEIIAPELL GFDVTEQNAI DQLLIELDGT ENKGKLGANA ILGVSMACAR 120
AAADFLQIPL YQYLGGFNSK TLPVPMMNIV NGGEHADNNV DIQEFMIMPV GAPNFREALR 180
MGAQIFHSLK SVLSAKGLNT AVGDEGGFAP NLGSNEEALQ TIVEAIEKAG FKPGEEVKLA 240
MDAASSEFYN KEDGKYHLSG EGVVKTSAEM VDWYEELVSK YPIISIEDGL DENDWEGHKL 300
LTERLGKKVQ LVGDDLFVTN TKKLSEGIKN GVGNSILIKV NQIGTLTETF DAIEMAKRAG 360
YTAVISHRSG ETEDSTIADI AVATNAGQIK TGAPSRTDRV AKYNQLLRIE DQLAETAQYH 420
GINSFYNLNK 430 |
Gene Ontology | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:magnesium ion binding; IEA:HAMAP. GO:0004634; F:phosphopyruvate hydratase activity; IEA:HAMAP. GO:0006096; P:glycolysis; IEA:HAMAP. GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |