CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024974
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sodium channel beta2 subunit 
Protein Synonyms/Alias
  
Gene Name
 Scn2b 
Gene Synonyms/Alias
 SCN2B 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
197KLSTDDLKTEEEGKMubiquitination[1]
203LKTEEEGKMDGEGNAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Ion channel; Ion transport; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 215 AA 
Protein Sequence
MHRDAWLPRP AFSLTGLSLF FSLVPPGRSM EVTAPTTLSV LNGSDTRLPC TFNSCYTVNH 60
KQFSLNWTYQ ECNNCTEEMF LQFRMKIINL KLERFGDRVE FSGNPSKYDV SVTLKNVQLE 120
DEGIYNCYIT NPPDRHRGHG KIYLQVLLEV PPERDSTVAV IVGASVGGFL AVVILVLMVV 180
KCVRRKKEQK LSTDDLKTEE EGKMDGEGNA EDGTK 215 
Gene Ontology
 GO:0001518; C:voltage-gated sodium channel complex; IEA:Compara.
 GO:0017080; F:sodium channel regulator activity; IEA:Compara.
 GO:0086006; F:voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential; IEA:Compara.
 GO:0060048; P:cardiac muscle contraction; IEA:Compara.
 GO:0007399; P:nervous system development; IEA:Compara.
 GO:0060371; P:regulation of atrial cardiac muscle cell membrane depolarization; IEA:Compara.
 GO:0086002; P:regulation of cardiac muscle cell action potential involved in contraction; IEA:Compara.
 GO:0086091; P:regulation of heart rate by cardiac conduction; IEA:Compara.
 GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IEA:Compara.
 GO:0046684; P:response to pyrethroid; IEA:Compara. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR013106; Ig_V-set.
 IPR000920; Myelin_P0. 
Pfam
 PF07686; V-set 
SMART
 SM00409; IG 
PROSITE
 PS50835; IG_LIKE 
PRINTS
 PR00213; MYELINP0.