| Tag | Content |
|---|
| CPLM ID | CPLM-015258 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Melanoma-associated antigen E1 |
Protein Synonyms/Alias | Alpha-dystrobrevin-associated MAGE Protein; DAMAGE; MAGE-E1 antigen |
Gene Name | Magee1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 730 | TKLPIPKKGILYYIG | ubiquitination | [1] | | 742 | YIGRECTKVFPDLLN | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex (By similarity). |
Sequence Annotation | DOMAIN 459 658 MAGE 1.
DOMAIN 706 897 MAGE 2.
REGION 704 918 Interaction with DTNA. |
Keyword | Cell membrane; Complete proteome; Cytoplasm; Membrane; Nucleus; Reference proteome; Repeat; Tumor antigen; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 918 AA |
Protein Sequence | MSLVSQNSRR RRGGRANARR NNGKGHPAAV PGPDVPRDRN DPKILQGLRA SEGPGTSMLP 60
TPREGPSASV PPTASEGSSA PRQFIISQGP NTSEMPTSRK GRGASRPPAV SAGLNTAMSI 120
TASEGPNSPV PPTAPKGSKA YEHLPVSEGL AISEQRHSDG GPNMEPTLGE GPGISVPPTF 180
SEESGISDEG LSIFMSPNIS EGPGINEPYS VSEDPSTSVP PTDSNGLGIN LPPTFGEGLS 240
ISMLFSALEE PDIFAPPPSA EGLFASMSPP SGEIQSSWVS PIIMEGCNVN VPPTSKKGLR 300
TSVPSAACES PSTSAEGLSS SLSSISAEGF CSSLAPCAAE GSCELLPCGE GRSTSELHCL 360
GEGSSTSQMS LAAEGPSASG MPTEANNPEE ALSCCASERR NKSTSRALQK AKDPSVRPKR 420
EDRFLDFQVL RDSKNSNSIT IMGLGTSRVA LTLKPQDPME QNVAELLQFL LLKDQTKYPI 480
KESDMREFID KDYRHQFPEI LRRAAVHLEC IFRFELKELD TEEHIYILLN KLGPVPFEGL 540
EDVPNGPKMG LLMMILGHIL LNGNQAREAD IWEMLWRFGV QRERRLSVFG NVKRLLSVEF 600
VWQRYLDYRP LTDCVPVEYE FYWGPRSRAE TTKMKILKFM AKIYNKDPMD WPALYNEALE 660
EDADRVVVNN FRVARPFRRP LFAEVAPELD ASGSKYSPHS WPESRLESKA RKLVQLFLLM 720
DSTKLPIPKK GILYYIGREC TKVFPDLLNR AARTLNHVYG TELVVLDPRN HSYTLYNRRE 780
MEDTEEIMDS PNRPGNNFLM QVLSFIFIMG NHARESAVWA FLRGLGVQNG RKHVITCRYL 840
SQRYLDSLRV PDSDPVQYDF VWGPRARLET SKMKALRYVA RIHRKEPEDW PEQYREAMED 900
EANRAEAGRR PLIVRNLR 918 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |