CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044744
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 N-lysine methyltransferase SETD6 
Protein Synonyms/Alias
  
Gene Name
 SETD6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
258EAALQGTKTEAERHLubiquitination[1, 2]
372DQGLLSNKEVYAKLSubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 404 AA 
Protein Sequence
MATQAKRPRV AGPVDGGDLD PVACFLSWCR RVGLELSPKV AVSRQGTVAG YGMVARESVQ 60
AGELLFVVPR AALLSQHTCS IGGLLERERV ALQSQSGWVP LLLALLHELQ APASRWRPYF 120
ALWPELGRLE HPMFCLRVRS LELYHQLVAL VMAYSFQEPL EEEEDEKEPN SPVMVPAADI 180
LNHLANHNAN LEYSANCLRM VATQPIPKGH EIFNTYGQMA NWQLIHMYGF VEPYPDNTDD 240
TADIQMVTVR EAALQGTKTE AERHLVYERW DFLCKLEMVG EEGAFVIGRE EVLTEEELTT 300
TLKVLCMPAE EFRELKDQDG GGDDKREEGS LTITNIPKLK ASWRQLLQNS VLLTLQTYAT 360
DLKTDQGLLS NKEVYAKLSW REQQALQVRY GQKMILHQLL ELTS 404 
Gene Ontology
  
Interpro
 IPR011383; RuBisCo-cyt_methylase.
 IPR015353; Rubisco_LSMT_subst-bd.
 IPR001214; SET_dom. 
Pfam
 PF09273; Rubis-subs-bind
 PF00856; SET 
SMART
 SM00317; SET 
PROSITE
  
PRINTS