UniProt Accession

 USPA_ECOLI; P0AED0; P28242; Q2M7F7 

Genbank Protein ID

 X67639; U00039; U00096; AP009048 

Genbank Nucleotide ID

 CAA47884.1; AAB18471.1; AAC76520.1; BAE77799.1 

Protein Name

 Universal stress protein A 

Protein Synonyms/Alias

  

Gene Name

 uspA 

Gene Synonyms/Alias

 b3495; JW3462 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
17	VDLSPESKVLVEKAV	acetylation	[1]
22	ESKVLVEKAVSMARP	acetylation	[1, 2]
100	QVLVDAIKKYDMDLV	acetylation	[1, 2]
101	VLVDAIKKYDMDLVV	acetylation	[1, 2]
118	HHQDFWSKLMSSARQ	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 

Functional Description

 Required for resistance to DNA-damaging agents. 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 144 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016020; C:membrane; IDA:UniProtKB.
 GO:0006950; P:response to stress; IEA:InterPro. 

Interpro

 IPR014729; Rossmann-like_a/b/a_fold.
 IPR006015; Universal_stress_UspA.
 IPR006016; UspA. 

Pfam

 PF00582; Usp 

SMART

  

PROSITE

  

PRINTS