CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038816
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Calcium/calmodulin-dependent protein kinase type II subunit gamma 
Protein Synonyms/Alias
  
Gene Name
 Camk2g 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
22STQEYAAKIINTKKLubiquitination[1]
36LSARDHQKLEREARIacetylation[2]
36LSARDHQKLEREARIubiquitination[1]
48ARICRLLKHPNIVRLacetylation[2]
48ARICRLLKHPNIVRLubiquitination[1]
117DIVHRDLKPENLLLAacetylation[2]
206HKLYQQIKAGAYDFPacetylation[2]
238MLTINPAKRITADQAacetylation[2]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 506 AA 
Protein Sequence
RGAFSVVRRC VKKTSTQEYA AKIINTKKLS ARDHQKLERE ARICRLLKHP NIVRLHDSIS 60
EEGFHYLVFD LVTGGELFED IVAREYYSEA DASHCIHQIL ESVNHIHQHD IVHRDLKPEN 120
LLLASKCKGA AVKLADFGLA IEVQGEQQAW FGFAGTPGYL SPEVLRKDPY GKPVDIWACG 180
VILYILLVGY PPFWDEDQHK LYQQIKAGAY DFPSPEWDTV TPEAKNLINQ MLTINPAKRI 240
TADQALKHPW VCQRSTVASM MHRQETVECL RKFNARRKLK GAILTTMLVS RNFSVGRQSS 300
APASPAASAA GLAGQAAKSL LNKKSDGGVK KRKSSSSVHL MEPQTTVVHN ATDGIKGSTE 360
SCNTTTEDED LKVRKQEIIK ITEQLIEAIN NGDFEAYTKI CDPGLTSFEP EALGNLVEGM 420
DFHKFYFENL LSKNSKPIHT TILNPHVHVI GEDAACIAYI RLTQYIDGQG RPRTSQSEET 480
RVWHRRDGKW LNVHYHCSGA PAAPLQ 506 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:InterPro.
 GO:0006816; P:calcium ion transport; IEA:Compara.
 GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Compara.
 GO:0046777; P:protein autophosphorylation; IEA:Compara. 
Interpro
 IPR020636; Ca/CaM-dep_Ca-dep_prot_Kinase.
 IPR013543; Ca/CaM-dep_prot_kinase-assoc.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF08332; CaMKII_AD
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS