CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006323
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S1-A 
Protein Synonyms/Alias
 RP10A 
Gene Name
 RPS1A 
Gene Synonyms/Alias
 PLC1; RPS10A; YLR441C; L9753.9 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
33RKEWFDIKAPSTFENubiquitination[1]
55VNKSTGLKSASDALKacetylation[2]
55VNKSTGLKSASDALKubiquitination[3]
62KSASDALKGRVVEVCubiquitination[3]
94RVDEVQGKNLLTNFHubiquitination[1]
109GMDFTTDKLRSMVRKubiquitination[1]
174VISEILTKEVQGSTLacetylation[2]
174VISEILTKEVQGSTLubiquitination[3]
242GSGEEKGKKVTGFKDubiquitination[1]
248GKKVTGFKDEVLETVacetylation[2]
248GKKVTGFKDEVLETVubiquitination[3]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [3] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
  
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine; partial.
 MOD_RES 245 245 Phosphothreonine.
 MOD_RES 254 254 Phosphothreonine.  
Keyword
 3D-structure; Acetylation; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 255 AA 
Protein Sequence
MAVGKNKRLS KGKKGQKKRV VDPFTRKEWF DIKAPSTFEN RNVGKTLVNK STGLKSASDA 60
LKGRVVEVCL ADLQGSEDHS FRKIKLRVDE VQGKNLLTNF HGMDFTTDKL RSMVRKWQTL 120
IEANVTVKTS DDYVLRIFAI AFTRKQANQV KRHSYAQSSH IRAIRKVISE ILTKEVQGST 180
LAQLTSKLIP EVINKEIENA TKDIFPLQNI HVRKVKLLKQ PKFDVGALMA LHGEGSGEEK 240
GKKVTGFKDE VLETV 255 
Gene Ontology
 GO:0030686; C:90S preribosome; IDA:SGD.
 GO:0022627; C:cytosolic small ribosomal subunit; NAS:SGD.
 GO:0003735; F:structural constituent of ribosome; NAS:SGD.
 GO:0002181; P:cytoplasmic translation; NAS:SGD.
 GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IGI:SGD. 
Interpro
 IPR027500; Ribosomal_S1/3_euk.
 IPR001593; Ribosomal_S3Ae.
 IPR018281; Ribosomal_S3Ae_CS. 
Pfam
 PF01015; Ribosomal_S3Ae 
SMART
  
PROSITE
 PS01191; RIBOSOMAL_S3AE 
PRINTS