CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034800
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Interferon regulatory factor 4 (Predicted) 
Protein Synonyms/Alias
 Protein Irf4 
Gene Name
 Irf4 
Gene Synonyms/Alias
 Irf4_predicted; rCG_44091 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
133RIVPEGAKKGAKQLTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 450 AA 
Protein Sequence
MNLETGSRGS EFGMSAVSCG NGKLRQWLID QIDSGKYPGL VWENEEKSVF RIPWKHAGKQ 60
DYNREEDAAL FKAWALFKGK FREGIDKPDP PTWKTRLRCA LNKSNDFEEL VERSQLDISD 120
PYKVYRIVPE GAKKGAKQLT LEDTQMAMGH PYPMTAPYGS LPTQQVHNYM MPPHDRSWRD 180
YAPDQSHPEI PYQCPVTFGP RGHHWQSPSC ENGCQVTGTF YACAPPESQA PGIPIEPSIR 240
SAEALALSDC RLHICLYYRD ILVKELTTSS PEGCRISHGH TYDVSNLDQV LFPYPDDNGQ 300
RKNIEKLLSH LERGLVLWMA PDGLYAKRLC QSRIYWDGPL ALSSDRPNKL ERDHTCKLFD 360
TQQFLSELQV FAHHGRPAPR FQVTLCFGEE FPDPQRQRKL ITAHVEPLLA RQLYFFAQQN 420
SGHFLRGYEL PEHISTPDYH RSLRHSSIQE 450 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0000788; C:nuclear nucleosome; IEA:Compara.
 GO:0000975; F:regulatory region DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0043966; P:histone H3 acetylation; IEA:Compara.
 GO:0043967; P:histone H4 acetylation; IEA:Compara.
 GO:0043011; P:myeloid dendritic cell differentiation; IEA:Compara.
 GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IEA:Compara.
 GO:0043388; P:positive regulation of DNA binding; IEA:Compara.
 GO:0045082; P:positive regulation of interleukin-10 biosynthetic process; IEA:Compara.
 GO:0045368; P:positive regulation of interleukin-13 biosynthetic process; IEA:Compara.
 GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IEA:Compara.
 GO:0045404; P:positive regulation of interleukin-4 biosynthetic process; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara. 
Interpro
 IPR019817; Interferon_reg_fac_CS.
 IPR001346; Interferon_reg_fact_DNA-bd_dom.
 IPR019471; Interferon_reg_factor-3.
 IPR017855; SMAD_dom-like.
 IPR008984; SMAD_FHA_domain.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00605; IRF
 PF10401; IRF-3 
SMART
 SM00348; IRF 
PROSITE
 PS00601; IRF_1
 PS51507; IRF_2 
PRINTS
 PR00267; INTFRNREGFCT.