UniProt Accession

 COA3_MOUSE; Q9D2R6; A2A4J6 

Genbank Protein ID

 AK019025; AL590969; BC026206 

Genbank Nucleotide ID

 BAB31515.1; CAM19561.1; AAH26206.1 

Protein Name

 Cytochrome c oxidase assembly protein 3 homolog, mitochondrial 

Protein Synonyms/Alias

 Coiled-coil domain-containing protein 56 

Gene Name

 Coa3 

Gene Synonyms/Alias

 Ccdc56 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
29	RIDPSREKLTPAQLQ	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).  

Keyword

 Acetylation; Coiled coil; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 108 AA 

Protein Sequence

Gene Ontology

 GO:0031305; C:integral to mitochondrial inner membrane; ISS:UniProtKB.
 GO:0033617; P:mitochondrial respiratory chain complex IV assembly; ISS:UniProtKB.
 GO:0070131; P:positive regulation of mitochondrial translation; ISS:UniProtKB. 

Interpro

 IPR018628; Coiled-coil_56. 

Pfam

 PF09813; Coiled-coil_56 

SMART

  

PROSITE

  

PRINTS