CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039346
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Peripherin 
Protein Synonyms/Alias
  
Gene Name
 Prph 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
183AEDLGALKQRLEEETacetylation[1]
291QEAEEWYKSKYADLSacetylation[1]
293AEEWYKSKYADLSDAacetylation[1]
372EEELRQLKEEMARHLacetylation[1]
401IEIATYRKLLEGEESacetylation[1]
401IEIATYRKLLEGEESubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Intermediate filament; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 473 AA 
Protein Sequence
MPSSASMSHH SSGLRSSISS TSYRRTFGPP PSLSPGAFSY SSSSRFSSSR LLGSGSPSSS 60
ARLGSFRAPR AGALRLPSER LDFSMAEALN QEFLATRSNE KQELQELNDR FANFIEKVRF 120
LEQQNAALRG ELSQARGQEP ARADQLCQQE LRELRRELEL LGRERDRVQV ERDGLAEDLG 180
ALKQRLEEET RKREDAEHNL VLFRKDVDDA TLSRLELERK IESLMDEIEF LKKLHEEELR 240
DLQVSVESQQ VQQVEVEATV KPELTAALRD IRAQYENIAA KNLQEAEEWY KSKYADLSDA 300
ANRNHEALRQ AKQEMNESRR QIQSLTCEVD GLRGTNEALL RQLRELEEQF ALEAGGYQAG 360
AARLEEELRQ LKEEMARHLR EYQELLNVKM ALDIEIATYR KLLEGEESRI SVPVHSFASL 420
SLKTTVPEVE PPQDSHSRKM VLIRTIETRD GEVVTESQKE QHSELDKSSI HSY 473 
Gene Ontology
 GO:0044299; C:C-fiber; IEA:Compara.
 GO:0005883; C:neurofilament; IEA:Compara.
 GO:0042622; C:photoreceptor outer segment membrane; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0045104; P:intermediate filament cytoskeleton organization; IEA:Compara. 
Interpro
 IPR016044; F.
 IPR001664; IF.
 IPR006821; Intermed_filament_DNA-bd.
 IPR018039; Intermediate_filament_CS.
 IPR002957; Keratin_I. 
Pfam
 PF00038; Filament
 PF04732; Filament_head 
SMART
  
PROSITE
 PS00226; IF 
PRINTS
 PR01248; TYPE1KERATIN.