CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039014
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serine/threonine-protein kinase TAO3 
Protein Synonyms/Alias
  
Gene Name
 Taok3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
521KQVATIEKEAKVAAAacetylation[1]
691ENQLEYNKRRERELHacetylation[1]
815LLNAYQSKIKMQTEAacetylation[1]
830QHERELQKLEQRVSLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 891 AA 
Protein Sequence
MRKGVLKDPE IAELFFKEDP EELFIDLHEI GHGSFGAVYF ATNAHTNEVV AIKKMSYSGK 60
QTHEKWQDIL KEVRFLQQLK HPNTIEYKGC YLKEHTAWLV MEYCLGSASD LLEVHKKPLQ 120
EVEIAAITHG ALQGLAYLHF HSLIHRDIKA GNILLTEPGQ VKLADFGSAS MASPANSFVG 180
TPYWMAPEVI LAMDEGQYDG KVDIWSLGIT CIELAERKPP LFNMNAMSAL YHIAQNDSPT 240
LQSREWTDSF RRFVDYCLHK IPQERPAAAE LLRHDFIRRE RPPRVLIDLI QRTKDAVREL 300
DNLQYRKMKK ILFQETRNGP LNESQEEEED SEQGSNLNRE VDSLGSIHSI PSVSVSTGSR 360
SSSVNSMQEV MDEGSPELVM MQEDEGTVNS SSSMVHKKDH VFVRDEAGHG DPRPEPRPTQ 420
SVQSRALHYR NRERFATIKS ASLVTRQIHE HEQENELREQ MSGYKRMRRQ HQKQLIALEN 480
KLKAEMDEHR LKLQKEVETH ANNSSIELEK LAKKQVATIE KEAKVAAADE KKFQQQILAQ 540
QKKDLTTFLE SQKKQYKICK EKIKEEMNED HSTPKKEKQE RISKHKENLQ HTQAEEEAHL 600
LTQQRLYYDR NCRCFKRKIM TKRHEVEQQN IREELNKKRT QKEMEHAMLI RHDESTRELE 660
YRQLHTLQKL RMDLIRLQHQ TELENQLEYN KRRERELHRK HVMELRQQPK NLKAMEMQIK 720
KQFQDTCKVQ TKQYKALKNH QLEVTPKNEH KAILKTLKEE QTRKLAILAE QYEQSINEMM 780
ASQALRLDEA QEAECQALRL QLQQEMELLN AYQSKIKMQT EAQHERELQK LEQRVSLRRA 840
HLEQKIEEEL AALQKERSER IKTLLERQER ETETFDMESL RMDLGSIVGL D 891 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:Compara.
 GO:0031572; P:G2 DNA damage checkpoint; IEA:Compara.
 GO:0000165; P:MAPK cascade; IEA:Compara.
 GO:0046329; P:negative regulation of JNK cascade; IEA:Compara.
 GO:0046330; P:positive regulation of JNK cascade; IEA:Compara.
 GO:0043507; P:positive regulation of JUN kinase activity; IEA:Compara.
 GO:0046777; P:protein autophosphorylation; IEA:Compara. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS