CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042629
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Pantothenate kinase 4 
Protein Synonyms/Alias
  
Gene Name
 PANK4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
29HEAFVYQKDSDPEFRubiquitination[1, 2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 473 AA 
Protein Sequence
XKEDVMTCLI KGCNFVLKNI PHEAFVYQKD SDPEFRFQTN HPHIFPYLLV NIGSGVSIVK 60
VETEDRFEWV GGSSIGGGTF WGLGALLTKT KKFDELLHLA SRGQHSNVDM LVRDVYGGAH 120
QTLGLSGNLI ASSFGKSATA DQEFSKEDMA KSLLHMISND IGQLACLHAR LHSLDRVYFG 180
GFFIRGHPVT MRTITYSINF FSKGEVQALF LRHEGYLGAI GAFLKGAEQD NPNQYSWGEN 240
YAGSSGLMSA SPELGPAQRA RSGTFDLLEM DRLERPLVDL PLLLDPPSYV PDTVDLTDDA 300
LARKYWLTCF EEALDGVVKR AVASQPDSVD AAERAEKFRQ KYWNKLQTLR QQPFAYGTLT 360
VRSLLDTREH CLNEFNFPDP YSKVKQRENG VALRCFPGVV RSLDALGWEE RQLALVKGLL 420
AGNVFDWGAK AVSAVLESDP YFGFEEAKRK LQERPWLVDS YSEWLQRLKI TVE 473 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004594; F:pantothenate kinase activity; IEA:InterPro.
 GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro. 
Interpro
 IPR002791; DUF89.
 IPR004567; Type_II_PanK. 
Pfam
 PF01937; DUF89
 PF03630; Fumble 
SMART
  
PROSITE
  
PRINTS