UniProt Accession

 KAPS_YEAST; Q02196; D6VXT6 

Genbank Protein ID

 X57990; S55315; X65124; Z28001; AY558261; BK006944 

Genbank Nucleotide ID

 CAA41055.1; AAB19854.1; CAA46252.1; CAA81833.1; AAS56587.1; DAA09156.1 

Protein Name

 Adenylyl-sulfate kinase 

Protein Synonyms/Alias

 ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase; APS kinase 

Gene Name

 MET14 

Gene Synonyms/Alias

 YKL001C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
69	NIRFGLNKDLGFSEK	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Catalyzes the synthesis of activated sulfate. 

Sequence Annotation

 NP_BIND 31 38 ATP (By similarity).
 ACT_SITE 105 105 Phosphoserine intermediate (By  

Keyword

 Amino-acid biosynthesis; ATP-binding; Complete proteome; Cysteine biosynthesis; Kinase; Methionine biosynthesis; Nucleotide-binding; Phosphoprotein; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 202 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0004020; F:adenylylsulfate kinase activity; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.
 GO:0070814; P:hydrogen sulfide biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
 GO:0019379; P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin); IMP:SGD.
 GO:0000096; P:sulfur amino acid metabolic process; IMP:SGD. 

Interpro

 IPR002891; APS_kinase.
 IPR027417; P-loop_NTPase. 

Pfam

 PF01583; APS_kinase 

SMART

  

PROSITE

  

PRINTS