UniProt Accession

 SURF4_HUMAN; O15260; O60923; Q5T8U6; Q9UNZ0; Q9UNZ1 

Genbank Protein ID

 AF078866; AF078867; AK315488; AL158826; CH471090; BC018741; BC111023; Y14820; Y17214 

Genbank Nucleotide ID

 AAD44498.1; AAD44499.1; BAG37872.1; CAI12840.1; EAW88071.1; AAH18741.1; AAI11024.1; CAA75099.1; CAA76692.1 

Protein Name

 Surfeit locus protein 4 

Protein Synonyms/Alias

  

Gene Name

 SURF4 

Gene Synonyms/Alias

 SURF-4 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
22	DQFLRVTKQYLPHVA	ubiquitination	[1]
139	AESRSEGKSMFAGVP	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. 

Sequence Annotation

 MOTIF 266 269 Di-lysine motif.  

Keyword

 Alternative splicing; Complete proteome; Endoplasmic reticulum; Golgi apparatus; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 269 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.
 GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0007030; P:Golgi organization; IMP:UniProtKB.
 GO:0010638; P:positive regulation of organelle organization; IMP:UniProtKB. 

Interpro

 IPR002995; Surf4. 

Pfam

 PF02077; SURF4 

SMART

  

PROSITE

 PS01339; SURF4 

PRINTS