UniProt Accession

 CALM_XENLA; P62155; P02593; P70667; P99014; Q61379; Q61380; Q6INP3 

Genbank Protein ID

 K01944; K01945; BC054973; BC072232; BC094079 

Genbank Nucleotide ID

 AAA49668.1; AAA49669.1; AAH54973.1; AAH72232.1; AAH94079.1 

Protein Name

 Calmodulin 

Protein Synonyms/Alias

 CaM 

Gene Name

 calm1; calm2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Xenopus laevis (African clawed frog) 

NCBI Taxa ID

 8355 

Lysine Modification

Position	Peptide	Type	References
95	EAFRVFDKDGNGYIS	acetylation	[1]

Reference

 [1] A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2.
 Andersen JL, Thompson JW, Lindblom KR, Johnson ES, Yang CS, Lilley LR, Freel CD, Moseley MA, Kornbluth S.
 Mol Cell. 2011 Sep 2;43(5):834-42. [PMID: 21884983] 

Functional Description

 Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. 

Sequence Annotation

 DOMAIN 8 43 EF-hand 1.
 DOMAIN 44 79 EF-hand 2.
 DOMAIN 81 116 EF-hand 3.
 DOMAIN 117 149 EF-hand 4.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 116 116 N6,N6,N6-trimethyllysine (By similarity).  

Keyword

 3D-structure; Acetylation; Calcium; Metal-binding; Methylation; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 149 AA 

Protein Sequence

Gene Ontology

 GO:0005509; F:calcium ion binding; IEA:InterPro. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR001125; Recoverin. 

Pfam

 PF13499; EF_hand_5 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS

 PR00450; RECOVERIN.