UniProt Accession

 B4DKQ5_HUMAN; B4DKQ5 

Genbank Protein ID

 AK296670 

Genbank Nucleotide ID

 BAG59267.1 

Protein Name

 cDNA FLJ54710, highly similar to Target of Myb protein 1 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
115	LVRTILPKNNPPTIV	ubiquitination	[1, 2]
156	IYEDLRRKGLEFPMT	ubiquitination	[1, 3]
320	FRTGQTTKAPSEAEP	ubiquitination	[1]
391	SSLADQRKEVKYEAP	ubiquitination	[1]
394	ADQRKEVKYEAPQAT	ubiquitination	[1, 2]
454	VTSEEFDKFLEERAK	ubiquitination	[2]
493	PRKKTQEKDDDMLFA	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

  

Sequence Annotation

  

Keyword

  

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 501 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 

Interpro

 IPR008942; ENTH_VHS.
 IPR004152; GAT.
 IPR014645; TOM1.
 IPR002014; VHS.
 IPR018205; VHS_subgr. 

Pfam

 PF03127; GAT
 PF00790; VHS 

SMART

 SM00288; VHS 

PROSITE

 PS50909; GAT
 PS50179; VHS 

PRINTS