UniProt Accession

 ZBT46_MOUSE; Q8BID6; A2AUD2; Q3U2R2; Q9D0G6; Q9D492 

Genbank Protein ID

 AK011461; AK016700; AK038975; AK155148; AL929094; BC058179 

Genbank Nucleotide ID

 BAB27633.1; BAB30386.1; BAC30190.1; BAE33078.1; CAM21496.1; AAH58179.1 

Protein Name

 Zinc finger and BTB domain-containing protein 46 

Protein Synonyms/Alias

 BTB-ZF protein expressed in effector lymphocytes; BZEL; BTB/POZ domain-containing protein 4 

Gene Name

 Zbtb46 

Gene Synonyms/Alias

 Btbd4 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
46	GKVFKAHKNVLLGSS	ubiquitination	[1]

Reference

 [1] A proteomics approach to identify the ubiquitinated proteins in mouse heart.
 Jeon HB, Choi ES, Yoon JH, Hwang JH, Chang JW, Lee EK, Choi HW, Park ZY, Yoo YJ.
 Biochem Biophys Res Commun. 2007 Jun 8;357(3):731-6. [PMID: 17451654] 

Functional Description

 Function as a transcriptional repressor for PRDM1. 

Sequence Annotation

 DOMAIN 31 99 BTB.
 ZN_FING 418 436 C2H2-type 1.
 ZN_FING 446 468 C2H2-type 2.
 CROSSLNK 46 46 Glycyl lysine isopeptide (Lys-Gly)  

Keyword

 Alternative splicing; Complete proteome; Isopeptide bond; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 600 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:2001199; P:negative regulation of dendritic cell differentiation; IMP:MGI.
 GO:0030853; P:negative regulation of granulocyte differentiation; IMP:MGI.
 GO:0045650; P:negative regulation of macrophage differentiation; IMP:MGI.
 GO:0045656; P:negative regulation of monocyte differentiation; IMP:MGI.
 GO:2001200; P:positive regulation of dendritic cell differentiation; IMP:MGI.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 

Pfam

 PF00651; BTB 

SMART

 SM00225; BTB
 SM00355; ZnF_C2H2 

PROSITE

 PS50097; BTB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 

PRINTS