CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030740
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DENN domain-containing protein 5A 
Protein Synonyms/Alias
 cDNA FLJ58453, highly similar to Rab6-interacting protein 1 
Gene Name
 DENND5A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
533EQMQNFDKASFLSDQubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 807 AA 
Protein Sequence
MSGGGGGGGS APSRFADYFV ICGLDTETGL EPDELSGENF EQTPLRRTFK SKVLARYPEN 60
VEWNPFDQDA VGMLCMPKGL AFKTQADPRE PQFHAFIITR EDGSRTFGFA LTFYEEVTSK 120
QICSAMQTLY HMHNAEYDVL HAPPADDRDQ SSMEDGEDTP VTKLQRFNSY DISRDTLYVS 180
KCICLITPMS FMKACRSVLE QLHQAVTSPQ PPPLPLESYI YNVLYEVPLP PPGRSLKFSG 240
VYGPIICQRP STNELPLFDF PVKEVFELLG VENVFQLFTC ALLEFQILLY SQHYQRLMTV 300
AETITALMFP FQWQHVYVPI LPASLLHFLD APVPYLMGLH SNGLDDRSKL ELPQEANLCF 360
VDIDNHFIEL PEDLPQFPNK LEFVQEVSEI LMAFGIPPEG NLHCSESASK LKRLRASELV 420
SDKRNGNIAG SPLHSYELLK ENETIARLQA LVKRTGVSLE KLEVREDPSS NKDLKVQCDE 480
EELRIYQLNI QIREVFANRF TQMFADYEVF VIQPSQDKES WFTNREQMQN FDKASFLSDQ 540
PEPYLPFLSR FLETQMFASF IDNKIMCHDD DDKDPVLRVF DSRVDKIRLL NVRTPTLRTS 600
MYQKCTTVDE AEKAIELRLA KIDHTAIHPH LLDMKIGQGK YEPGFFPKLQ SDVLSTGPAS 660
NKWTKRNAPA QWRRKDRQKQ HTEHLRLDND QREKYIQEAR TMGSTIRQPK LSNLSPSVIA 720
QTNWKFVEGL LKECRNKTKR MLVEKMGREA VELGHGEVNI TGVEENTLIA SLCDLLERIW 780
SHGLQVKQEY FLIQNVGSLM PAHSCLP 807 
Gene Ontology
  
Interpro
 IPR005112; dDENN_dom.
 IPR001194; DENN_dom.
 IPR005113; uDENN_dom. 
Pfam
 PF03455; dDENN
 PF02141; DENN
 PF03456; uDENN 
SMART
 SM00801; dDENN
 SM00799; DENN
 SM00800; uDENN 
PROSITE
 PS50947; DDENN
 PS50211; DENN
 PS50946; UDENN 
PRINTS