CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable JmjC domain-containing histone demethylation protein 2C 
Protein Synonyms/Alias
  
Gene Name
 JMJD1C 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
131VSQPVAQKQECKVSTacetylation[1]
647SMGAPSSKSGRTMPNubiquitination[1, 2, 3]
730SSNWKLFKECWKQGQubiquitination[2]
843EYCNPEGKFNLASHLubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 956 AA 
Protein Sequence
XDSMPAMQLA SKDRVSERSS AGAHKTDCLK LAEAGETGRI ILPNVNSDSV HTKSEKNFQA 60
VSQGSVPSSV MSAVNTMCNT KTDVITSAAD TTSVSSWGGS EVISSLSNTI LASTSSECVS 120
SKSVSQPVAQ KQECKVSTTA PVTLASSKTG SVVQPSSGFS GTTDFIHLKK HKAALAAAQY 180
KSSNASETEP NAIKNQTLSA SLPLDSTVIC STINKANSVG NGQASQTSQP NYHTKLKKAW 240
LTRHSEEDKN TNKMENSGNS VSEIIKPCSV NLIASTSSDI QNSVDSKIIV DKYVKDDKVN 300
RRKAKRTYES GSESGDSDES ESKSEQRTKR QPKPTYKKKQ NDLQKRKGEI EEDLKPNGVL 360
SRSAKERSKL KLQSNSNTKI AWKRAVRGVR EMCDACEATL FNIHWVCQKC GFVVCLDCYK 420
AKERKSSRDK ELYAWMKCVK GQPHDHKHLM PTQIIPGSVL TDLLDAMHTL REKYGIKSHC 480
HCTNKQNLQV GNFPTMNGVS QVLQNVLNHS NKISLCMPES QQQNTPPKSE KNGGSSPESD 540
VGTDNKLTPP ESQSPLHWLA DLAEQKAREE KKENKELTLE NQIKEEREQD NSESPNGRTS 600
PLVSQNNEQG STLRDLLTTT AGKLRVGSTD AGIAFAPVYS MGAPSSKSGR TMPNILDDII 660
ASVVENKIPP SKTSKINVKP ELKEEPEESI ISAVDENNKL YSDIPHSWIC EKHILWLKDY 720
KNSSNWKLFK ECWKQGQPAV VSGVHKKMNI SLWKAESISL DFGDHQADLL NCKDSIISNA 780
NVKEFWDGFE EVSKRQKNKS GETVVLKLKD WPSGEDFKTM MPARYEDLLK SLPLPEYCNP 840
EGKFNLASHL PGFFVRPDLG PRLCSAYGVV AAKDHDIGTT NLHIEVSDVV NILVYVGIAK 900
GNGILSKAGI LKKFEEEDLD DILRKRLKDS SEIPGALWHI YAGKDVDKIR EFLQKV 956 
Gene Ontology
  
Interpro
 IPR003347; JmjC_dom. 
Pfam
  
SMART
 SM00558; JmjC 
PROSITE
 PS51184; JMJC 
PRINTS