UniProt Accession

 E2QRK0_HUMAN; E2QRK0 

Genbank Protein ID

 AL354836 

Genbank Nucleotide ID

  

Protein Name

 Laminin subunit alpha-5 

Protein Synonyms/Alias

  

Gene Name

 LAMA5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
83	PTEDLYCKLVGGPVA	ubiquitination	[1]
113	CTAANSNKAHPASNA	ubiquitination	[1]
192	WQFFASSKRDCLERF	ubiquitination	[1, 2, 3, 4]
292	RRYYYSIKDISIGGR	ubiquitination	[1, 3]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Disulfide bond; Laminin EGF-like domain; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 528 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR002049; EGF_laminin.
 IPR008211; Laminin_N. 

Pfam

 PF00053; Laminin_EGF
 PF00055; Laminin_N 

SMART

 SM00180; EGF_Lam
 SM00136; LamNT 

PROSITE

 PS01248; EGF_LAM_1
 PS50027; EGF_LAM_2
 PS51117; LAMININ_NTER 

PRINTS