CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028688
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Folylpolyglutamate synthase, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Fpgs 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
37SGSAYEAKTASFQDAubiquitination[1]
62ASYLEQVKRQRSDPQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 243 AA 
Protein Sequence
MMKSTRCLPM SWPVAEKFWW EAAMEWKDPS GSAYEAKTAS FQDAVRTLNT LQTNASYLEQ 60
VKRQRSDPQA QLEAMEMYLA RSGLQVEDLN RLNIIHVTGT KGKGSTCAFT ERILRNYGLK 120
TGFFSSPHMV QVRERIRING KPISPELFTK HFWCLYNQLE EFKDDSHVSM PSYFRFLTLM 180
AFHVFLQEKV DLAVVEVGIG GAFDCTNIIR KPVVCGVSSL GIDHTSLLGD TVEKIAWQKG 240
GIF 243 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:InterPro.
 GO:0046901; P:tetrahydrofolylpolyglutamate biosynthetic process; IEA:GOC. 
Interpro
 IPR001645; Folylpolyglutamate_synth.
 IPR018109; Folylpolyglutamate_synth_CS.
 IPR013221; Mur_ligase_cen. 
Pfam
  
SMART
  
PROSITE
 PS01011; FOLYLPOLYGLU_SYNT_1
 PS01012; FOLYLPOLYGLU_SYNT_2 
PRINTS