CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017210
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syntaxin-5 
Protein Synonyms/Alias
  
Gene Name
 Stx5 
Gene Synonyms/Alias
 Stx5a 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
69QEFQSACKSLQSRQNubiquitination[1]
114NTFAKLEKLTILAKRubiquitination[1]
120EKLTILAKRKSLFDDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Mediates endoplasmic reticulum to Golgi transport (By similarity). 
Sequence Annotation
 DOMAIN 263 325 t-SNARE coiled-coil homology.  
Keyword
 Alternative initiation; Coiled coil; Complete proteome; Golgi apparatus; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 355 AA 
Protein Sequence
MIPRKRYGSK NTDQGVYLGL SKTQVLSPAT AISSSSDSTP LPTPVALVPS PPDTMSCRDR 60
TQEFQSACKS LQSRQNGIQT SKPALHAARQ CSEFTLMARR IGKDLSNTFA KLEKLTILAK 120
RKSLFDDKAV EIEELTYIIK QDINSLNKQI AQLQDFVRAK GSQSGRHLQT HSNTIVVSLQ 180
SKLASMSNDF KSVLEVRTEN LKQQRNRREQ FSRAPVSALP LAPNNLGGGP IILGAESRAS 240
RDVAIDMMDP RTSQQLQLID EQDSYIQSRA DTMQNIESTI VELGSIFQQL AHMVKEQEET 300
IQRIDENVLG AQLDVEAAHS EILKYFQSVT SNRWLMVKIF LILIVFFIIF VVFLA 355 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; TAS:MGI.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0031201; C:SNARE complex; IEA:Compara.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Compara.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0042147; P:retrograde transport, endosome to Golgi; IEA:Compara.
 GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:Compara.
 GO:0016192; P:vesicle-mediated transport; TAS:MGI. 
Interpro
 IPR006012; Syntaxin/epimorphin_CS.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE
 PF00804; Syntaxin 
SMART
 SM00397; t_SNARE 
PROSITE
 PS00914; SYNTAXIN
 PS50192; T_SNARE 
PRINTS