CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002596
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Clathrin light chain B 
Protein Synonyms/Alias
 Lcb 
Gene Name
 Cltb 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
133QEWREKAKKDLEEWNacetylation[1]
134EWREKAKKDLEEWNQacetylation[1]
184EAFVKESKEETPGTEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. 
Sequence Annotation
 REGION 93 155 Involved in binding clathrin heavy chain.
 MOD_RES 11 11 Phosphoserine (By similarity).
 MOD_RES 13 13 Phosphoserine (By similarity).
 DISULFID 199 209 By similarity.  
Keyword
 Alternative splicing; Calcium; Coated pit; Complete proteome; Cytoplasmic vesicle; Direct protein sequencing; Disulfide bond; Membrane; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 229 AA 
Protein Sequence
MAEDFGFFSS SESGAPEAAE EDPAAAFLAQ QESEIAGIEN DSGFGAPAAS QVASAQPGLA 60
SGGGSEDMGT TVNGDVFQEA NGPADGYAAI AQADRLTQEP ESIRKWREEQ KKRLQELDAA 120
SKVTEQEWRE KAKKDLEEWN QRQSEQVEKN KINNRIADKA FYQQPDADTI GYVASEEAFV 180
KESKEETPGT EWEKVAQLCD FNPKSSKQCK DVSRLRSVLM SLKQTPLSR 229 
Gene Ontology
 GO:0060170; C:cilium membrane; IEA:Compara.
 GO:0030132; C:clathrin coat of coated pit; NAS:UniProtKB.
 GO:0030130; C:clathrin coat of trans-Golgi network vesicle; IEA:InterPro.
 GO:0030125; C:clathrin vesicle coat; NAS:UniProtKB.
 GO:0005802; C:trans-Golgi network; IEA:Compara.
 GO:0005326; F:neurotransmitter transporter activity; NAS:UniProtKB.
 GO:0042277; F:peptide binding; IDA:RGD.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0007269; P:neurotransmitter secretion; NAS:UniProtKB.
 GO:0016183; P:synaptic vesicle coating; NAS:UniProtKB. 
Interpro
 IPR000996; Clathrin_L-chain. 
Pfam
 PF01086; Clathrin_lg_ch 
SMART
  
PROSITE
 PS00224; CLATHRIN_LIGHT_CHN_1
 PS00581; CLATHRIN_LIGHT_CHN_2 
PRINTS