| Tag | Content |
|---|
| CPLM ID | CPLM-009169 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Hermansky-Pudlak syndrome 5 protein homolog |
Protein Synonyms/Alias | Ruby-eye protein 2; Ru2 |
Gene Name | Hps5 |
Gene Synonyms/Alias | Ru2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 543 | LVSLQAVKDSVSSFV | ubiquitination | [1] | | 632 | PLVLFEPKVLRMVLL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins. |
Sequence Annotation | MOD_RES 509 509 Phosphoserine.
MOD_RES 532 532 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1126 AA |
Protein Sequence | MTFVPVIPEA YSHVLAEFES LDPLLTALRL DSSRLRCTSI AVSRKWLALG STGGGLNLIQ 60
KDGWKQRLFL SHREGAISQI ACCSHDDDYV AVATSQGLVV VWELNQERRG KPERIHVSSE 120
HKGRKVTALC WDTAVLRVFV GDHVGKVSAI KLNTLKQAKA AAAFVMFPVQ TVLTVDSCVV 180
QLDYLDGRLL VSSLTRSFLC DTEREKFWKI GNKERHGEYG ACFFPGRCAG GQQPVIYCAR 240
PGSRMWEVNF DGEVLSTHQF KKLLSMPPLP VITARSEPQY DHTVGSSQSL AFPKLLHLSE 300
HCVLTWTEKG IYIFIPQNVQ VLLWSEVKDI QDVAVYKNEL FCLHFNGKIS HLSLLSVERC 360
VERLLRRGLW DLAARTCCLF QNSIITSRAR KTLTADKLEH LKSQLDLTAC SELISQLDDL 420
ILRFEPLESA CSSRRSSISS HESFSILDSG IYRIISSRRG SQSDEDSCSL HSQTFSEDER 480
LKEFASHQEE EQPEQGCGAN RNEESASHSP VMSEVDKSEA FLPFSIALPF RSPSPLVSLQ 540
AVKDSVSSFV RKTTEKIGTL HGSPELKEPF ESKDADRAHE EEVSAVTCPL EEDTEEKEIH 600
QPPKEDRLQE LTAATAEAMT KLLDPLVLFE PKVLRMVLLE WLSQLEKTFA MKDFPGISNT 660
SSPTVKSNLG AHLLGETEKR VLDEESGEGR RVSLVTEEAG GQITCDPVSN LSEPSADRFR 720
VCSPYAITNS LQRDLAELTT LCLELNVLTS AMESVGGHVD RASQQLSPEI LACRFLKKYF 780
FLLDLKRAKE SIKLTYDSPC VWDTFVEGLK EMARSNPAYT ELEEGDLPTG LQLLDGSVPS 840
DSPLLIAFAT RLYDRFGESA LRACIKFYPS ISPSDIAQLC RHHPAQFLAY LDSLVKSRPE 900
DQWPSFLEFL LQPESLRLEW LLLAVSHDAP PSTSTVDDEG HPRPHSHLLS WGYSQLILLL 960
IKLPADFTTK EKMTDICRSY GFWPGYLTLC LELERRREAF TNIVYLNDIS LMEGDNGWIP 1020
ETLEEWKLLL HLLQTKSTRP APQESLNGSL SDGPAPINVE NVALLLAKAM GPDRAWSLLQ 1080
ECGLALELSE KFTRTCDILR IAERRQRALI QGMLEKCDRF LWSQQA 1126 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |