CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020988
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial import receptor subunit TOM20 homolog 
Protein Synonyms/Alias
 Mitochondrial 20 kDa outer membrane protein; Outer mitochondrial membrane receptor Tom20 
Gene Name
 Tomm20 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
61LSKLPDLKDAEAVQKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity). 
Sequence Annotation
 MOD_RES 135 135 Phosphoserine.
 MOD_RES 138 138 Phosphoserine.  
Keyword
 Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 145 AA 
Protein Sequence
MVGRNSAIAA GVCGALFIGY CIYFDRKRRS DPNFKNRLRE RRKKQKLAKE RAGLSKLPDL 60
KDAEAVQKFF LEEIQLGEEL LAQGDYEKGV DHLTNAIAVC GQPQQLLQVL QQTLPPPVFQ 120
MLLTKLPTIS QRIVSAQSLA EDDVE 145 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005740; C:mitochondrial envelope; IDA:MGI.
 GO:0005742; C:mitochondrial outer membrane translocase complex; IEA:InterPro.
 GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; ISS:HGNC.
 GO:0051082; F:unfolded protein binding; ISS:HGNC.
 GO:0006626; P:protein targeting to mitochondrion; ISS:HGNC. 
Interpro
 IPR002056; MAS20_rcpt-related.
 IPR022422; MAS20_rcpt_metazoan.
 IPR023392; Tom20_dom. 
Pfam
 PF02064; MAS20 
SMART
  
PROSITE
  
PRINTS
 PR01989; EUOM20RECPTR.
 PR00351; OM20RECEPTOR.