UniProt Accession

 RRS1_MOUSE; Q9CYH6; Q3UQW6; Q9CS27; Q9D2B2; Q9D6M6; Q9JJC1 

Genbank Protein ID

 AB041589; AK010178; AK017683; AK019257; AK019913; AK142041; BC003481; BC055925 

Genbank Nucleotide ID

 BAA95072.1; BAB26750.1; BAB30871.1; BAB31631.1; BAB31912.1; BAE24922.1; AAH03481.1; AAH55925.1 

Protein Name

 Ribosome biogenesis regulatory protein homolog 

Protein Synonyms/Alias

  

Gene Name

 Rrs1 

Gene Synonyms/Alias

 Rrr; MNCb-2643 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
12	RVEELLAKAEQEEAE	acetylation	[1, 2]
265	FGDFAAEKKNQLELL	ubiquitination	[3]

Reference

 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Involved in ribosome biogenesis (By similarity). 

Sequence Annotation

 MOD_RES 1 1 N-acetylmethionine (By similarity).  

Keyword

 Acetylation; Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 365 AA 

Protein Sequence

Gene Ontology

 GO:0000794; C:condensed nuclear chromosome; IEA:Compara.
 GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.
 GO:0005730; C:nucleolus; IDA:UniProtKB.
 GO:0007080; P:mitotic metaphase plate congression; IEA:Compara.
 GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. 

Interpro

 IPR007023; Ribosom_reg. 

Pfam

 PF04939; RRS1 

SMART

  

PROSITE

  

PRINTS