UniProt Accession

 MSRB3_MOUSE; Q8BU85 

Genbank Protein ID

 AC138388; AK086975; AK137163; BC096447 

Genbank Nucleotide ID

 BAC39776.1; BAE23258.1; AAH96447.1 

Protein Name

 Methionine-R-sulfoxide reductase B3, mitochondrial 

Protein Synonyms/Alias

 MsrB3 

Gene Name

 Msrb3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
102	CRDKKNCKVVFSQQE	acetylation	[1, 2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

 Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine (By similarity). 

Sequence Annotation

 MOTIF 250 253 Endoplasmic reticulum retention signal.
 ACT_SITE 218 218 Nucleophile (By similarity).
 METAL 146 146 Zinc (By similarity).
 METAL 149 149 Zinc (By similarity).
 METAL 195 195 Zinc (By similarity).
 METAL 198 198 Zinc (By similarity).  

Keyword

 Complete proteome; Endoplasmic reticulum; Metal-binding; Oxidoreductase; Reference proteome; Signal; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 253 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; ISS:HGNC.
 GO:0005739; C:mitochondrion; ISA:MGI.
 GO:0033743; F:peptide-methionine (R)-S-oxide reductase activity; ISS:HGNC.
 GO:0008270; F:zinc ion binding; ISS:HGNC.
 GO:0030091; P:protein repair; ISS:HGNC. 

Interpro

 IPR002579; Met_Sox_Rdtase_MsrB.
 IPR011057; Mss4-like. 

Pfam

 PF01641; SelR 

SMART

  

PROSITE

  

PRINTS