CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037167
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Piezo-type mechanosensitive ion channel component 2 
Protein Synonyms/Alias
  
Gene Name
 PIEZO2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
43KLEDLGLKQFTVAELubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 563 AA 
Protein Sequence
MSVVIYTMLV LIFIYTYQFE NFPGLWQNMT GLKKEKLEDL GLKQFTVAEL FTRIFIPTSF 60
LLVCILHLHY FHDRFLELTD LKSIPSKEDN TIYSHAKVNG RVYLIINSIK KKLPIHQNEL 120
AHPEGSLPDL TMMHLTASLE KPEVRKLAEP GEEKLEGYSE KAQKGDLGKD SEESEEDGEE 180
EEESEEEEET SDLRNKWHLV IDRLTVLFLK FLEYFHKLQV FMWWILELHI IKIVSSYIIW 240
VSVKEVSLFN YVFLISWAFA LPYAKLRRLA SSVCTVWTCV IIVCKMLYQL QTIKPENFSV 300
NCSLPNENQT NIPFNELNKS LLYSAPIDPT EWVGLRKSSP LLVYLRNNLL MLAILAFEVT 360
IYRHQEYYRG RNNLTAPVSR TIFHDITRLH LDDGLINCAK YFINYFFYKF GLETCFLMSV 420
NVIGQRMDFY AMIHACWLIA VLYRRRRKAI AEIWPKYCCF LACIITFQYF ICIGIPPAPC 480
RDYPWRFKGA SFNDNIIKWL YFPDFIVRPN PVFLVYDFML LLCASLQRQI FEDENKAAVR 540
IMAGDNVEIC MNLDAASFSQ HNP 563 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0008381; F:mechanically-gated ion channel activity; IEA:InterPro. 
Interpro
 IPR027272; Piezo. 
Pfam
  
SMART
  
PROSITE
  
PRINTS