UniProt Accession

 OLA1_RAT; A0JPJ7 

Genbank Protein ID

 BC127457 

Genbank Nucleotide ID

 AAI27458.1 

Protein Name

 Obg-like ATPase 1 

Protein Synonyms/Alias

  

Gene Name

 Ola1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
242	DYIRKKNKWLIKIKE	acetylation	[1]
246	KKNKWLIKIKEWVDK	acetylation	[1]
248	NKWLIKIKEWVDKSD	acetylation	[1]
294	MTQSALPKIIKAGFA	acetylation	[1]
294	MTQSALPKIIKAGFA	ubiquitination	[2]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP (By similarity). 

Sequence Annotation

 DOMAIN 24 131 G.
 NP_BIND 32 37 ATP (By similarity).
 MOTIF 267 274 Nuclear export signal (Potential).
 BINDING 231 231 ATP; via carbonyl oxygen (By similarity).
 MOD_RES 294 294 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; ATP-binding; Complete proteome; Cytoplasm; Hydrolase; Nucleotide-binding; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 396 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0006200; P:ATP catabolic process; IEA:Compara. 

Interpro

 IPR012675; Beta-grasp_dom.
 IPR004396; CHP00092.
 IPR013029; DUF933.
 IPR006073; GTP_binding_domain.
 IPR027417; P-loop_NTPase.
 IPR012676; TGS-like.
 IPR023192; TGS-like_dom. 

Pfam

 PF01926; MMR_HSR1
 PF06071; YchF-GTPase_C 

SMART

  

PROSITE

  

PRINTS

 PR00326; GTP1OBG.