CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002476
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S19-A 
Protein Synonyms/Alias
 RP55A; S16a; YP45; YS16A 
Gene Name
 RPS19A 
Gene Synonyms/Alias
 RP55A; RPS16AA; YOL121C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
27SFLQRQGKLEVPGYVacetylation[1]
27SFLQRQGKLEVPGYVubiquitination[2]
56DAEGWFYKRAASVARacetylation[1]
56DAEGWFYKRAASVARubiquitination[2]
78VGVGKLNKLYGGAKSacetylation[1]
78VGVGKLNKLYGGAKSubiquitination[2]
84NKLYGGAKSRGVRPYubiquitination[2]
92SRGVRPYKHIDASGSacetylation[1]
103ASGSINRKVLQALEKubiquitination[2]
110KVLQALEKIGIVEISacetylation[1]
110KVLQALEKIGIVEISubiquitination[2]
119GIVEISPKGGRRISEubiquitination[2]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Required for proper maturation of the small (40S) ribosomal subunit. Binds to 40s pre-ribosomal particles, probably required after association of NOC4 but before association of ENP1, TSR1 and RIO2 with 20/21S pre-rRNA. 
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome; Ribonucleoprotein; Ribosomal protein; Ribosome biogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 144 AA 
Protein Sequence
MPGVSVRDVA AQDFINAYAS FLQRQGKLEV PGYVDIVKTS SGNEMPPQDA EGWFYKRAAS 60
VARHIYMRKQ VGVGKLNKLY GGAKSRGVRP YKHIDASGSI NRKVLQALEK IGIVEISPKG 120
GRRISENGQR DLDRIAAQTL EEDE 144 
Gene Ontology
 GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; IDA:SGD.
 GO:0002181; P:cytoplasmic translation; IC:SGD.
 GO:0042274; P:ribosomal small subunit biogenesis; IMP:SGD.
 GO:0006407; P:rRNA export from nucleus; IMP:SGD. 
Interpro
 IPR001266; Ribosomal_S19e.
 IPR018277; Ribosomal_S19e_CS. 
Pfam
 PF01090; Ribosomal_S19e 
SMART
  
PROSITE
 PS00628; RIBOSOMAL_S19E 
PRINTS