CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007261
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein DSE1 
Protein Synonyms/Alias
 Daughter-specific expression protein 1 
Gene Name
 DSE1 
Gene Synonyms/Alias
 YER124C; SYGP-ORF48 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
41MTLSTYKKTWQNNTSubiquitination[1]
49TWQNNTSKMNSPILRubiquitination[1]
241SLFIYDLKSNLDCIKubiquitination[1]
358VCELYAKKGYIESLKubiquitination[1]
438SDKNICLKSNDTKANubiquitination[1]
553QEDIVFTKRMYSVNDubiquitination[1, 2]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Involved in cell wall metabolism and required for the separation of the mother and daughter cells. 
Sequence Annotation
 REPEAT 144 185 WD 1.
 REPEAT 315 351 WD 2.
 REPEAT 356 395 WD 3.
 REPEAT 397 448 WD 4.  
Keyword
 Cell cycle; Cell division; Cell wall biogenesis/degradation; Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 573 AA 
Protein Sequence
MQDTKYYEPT NIFRQPAINI KKRSDKKRIL QSMMTLSTYK KTWQNNTSKM NSPILRKASD 60
NFNDYYTTKK LKSDYWKLYG VDESELSIPS DMSIVDNILL VSTMNEKDNL KLFEISAEKK 120
LKELQTITVP GKPITCICLL PMVDFPPQIF PSSQINPNHN QLILTGHQDG IVNLIATSTY 180
KGCAKIIKRF NHNKFLKSTV STSIPILEIT PKTAPILKVS PWNKTGFVSL LNDSLFIYDL 240
KSNLDCIKTP IFLQSYPGIN SFAVNEFHDP FLLALVGSKF GPNGISLLDL RTNLYIPDIL 300
DNSISAGCGK DHLQRKNTSL DCVWISNHHV AQSLNDKIQI WDIQSCDGKP VCELYAKKGY 360
IESLKFNENT GALYSSDDQG FVICWDLQNL QNMKYGELVH GFNSISLDSE SELLLTKQVF 420
QCGNIIVSGM SDKNICLKSN DTKANGKGCG FLFLDMANDG SLVTLDNFCE LGLHQICQVQ 480
FNVDTGKIID GNGTGKSGIS DSSMLSLSNE SDHSMTETSD DMFSNSGNWD CSSANTVSEG 540
RLNDDQEDIV FTKRMYSVND VHLSGSTIDT TVV 573 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0007109; P:cytokinesis, completion of separation; IMP:SGD.
 GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.
 GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD. 
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
  
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS