CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013932
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pre-rRNA-processing protein TSR1 homolog 
Protein Synonyms/Alias
  
Gene Name
 Tsr1 
Gene Synonyms/Alias
 Kiaa1401 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
726REDVMWFKPVELRTKacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
 Required during maturation of the 40S ribosomal subunit in the nucleolus (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 803 AA 
Protein Sequence
MAAHRSGPLK QQNKAHKGGR HHGGGSAQRD SKGRVGPKIL CKKLKRQLSR IDQRHRASQL 60
RKQKRESVLA EKRQLGSKDG PPHQVLVVPL HSRISLPEAF KLLQNEDLGT VYLSERGSTQ 120
SFMLLCPSLK HRWFFTYARP GDLHTLLDMA KVADTILFLL DPLEGWDSTG DYCLSCLFAQ 180
GLPTYTLAVQ GLSGFPPKKQ IDARKKLSKM VEKRFPEDKL LLLDTQQESG MLLRQLANQK 240
QRHLAFRDRR AYLFAHVADF VPSEESDLVG TLKISGYVRG RTLNVNSLLH IVGHGDFQMN 300
QIDAPVDPFP LNPRVIKSQK KPNMAMEVCV TDAAPDMEED LKVLMKADPD HQESLQTEAI 360
PDPMEGEQTW PTEEELDEAD DLLKQRSRVV KKVPKGTSSY QAEWILDEGD ESDGEGGEYD 420
DIQHEGFMEE ESQDGSGEEE EEECETMTLG ESVRDDLYDE KVDAEDEERM LEKYKQERLE 480
EMFPDEMDTP RDVAARIRFQ KYRGLKSFRT SPWDPKENLP RDYARIFQFQ NFVNTRKRIF 540
KEIEEKEAEG AEVGWYVTLH VSDVPVSVVE YFRQGAPLIA FSLLPYEQKM SVLNMVVSRN 600
PGNTEPVKAK EELIFHCGFR RFRASPLFSQ HTAADKHKFQ RFLTADAAFV VTVFAPITFP 660
PASVLLFKQR RNGMHSLIAT GHLFSVDPDR MVIKRVVLSG HPFKIFTKMA VVRYMFFNRE 720
DVMWFKPVEL RTKWGRRGHI KEPLGTHGHM KCSFDGKLKS QDTVLMNLYK RVFPKWTYDP 780
YVPEPVPWVK SDISSTVSEV DME 803 
Gene Ontology
 GO:0005730; C:nucleolus; ISS:UniProtKB.
 GO:0042255; P:ribosome assembly; ISS:UniProtKB. 
Interpro
 IPR012948; AARP2CN.
 IPR007034; BMS1_TSR1_C. 
Pfam
 PF08142; AARP2CN
 PF04950; DUF663 
SMART
 SM00785; AARP2CN 
PROSITE
  
PRINTS